Sentences with phrase «molecular biological studies»

The results suggest caution when interpreting data from molecular biological studies or developing gene therapies to treat various diseases.

Further molecular biological studies by the scientists demonstrated that methylation in the non-coding region of the Igfbp2 gene contributes to less IGFBP2 synthesis.

«In addition, there are plans for further molecular biological studies with the objective of understanding exactly how the 5 - LO inhibitors act on the leukaemic cells.»

Not exact matches

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

Editor's Note (10/2/17): Seventeen years before the Nobel Prize in Physiology or Medicine went to three U.S. scientists for their research on biological clocks, one of them, Michael W. Young, set out an account in Scientific American describing the genetic studies that identified the «molecular timepieces» that are ubiquitous throughout the animal kingdom.

Earlier, for his Ph.D., he used his physics training to study biological interactions at the molecular resolution — but for his postdoc he changed approaches dramatically, turning to cell biology and applying his skills to the development of high - resolution functional imaging of DNA transcription in living cells.

With the gross architecture of the cell now well known, most living laureates who have studied biological systems, such as Steitz, worked at the molecular level.

Co-authors of the study include: Jean - Sébastien Jouhanneau, Leiron Ferrarese, Luc Estebanez and James F.A. Poulet from the Department of Neuroscience at the Max Delbrück Center for Molecular Medicine in Berlin and the Neuroscience Research Center at the Charité - Universitätsmedizin Berlin; Nick J. Audette, a doctoral student in the Department of Biological Sciences at Carnegie Mellon and the CNBC; and Michael Brecht from the Bernstein Center for Computational Neuroscience at Humboldt University in Berlin and the the Neuroscience Research Center at the Charité - Universitätsmedizin Berlin.

«This research shows the intricate workings of a biological pathway crucial to the development of Huntington's disease, and is highly relevant to drug development,» said study leader Beverly L. Davidson, Ph.D., director of The Center for Cellular and Molecular Therapeutics at The Children's Hospital of Philadelphia (CHOP).

Neela Yennawar, director of the Huck Institute's Macromolecular X-ray Facility at Penn State and a co-author on the paper in Small, said «Crystallographers are pushing the boundary of biological samples being studied and moving towards more difficult targets of higher molecular weight and complexity.

Most scientists who study the transport of materials within a cell have focused on the drivers of that transport — namely, molecular motors, a family of biological agents that actively convert a cell's energy into mechanical work to move cargo across a cell.

Chris Meisinger is a research group leader at the Institute of Biochemistry and Molecular Biology and a member of the Cluster of Excellence BIOSS Centre for Biological Signalling Studies.

In a study spanning molecular genetics, stem cells and the sciences of both brain and behavior, researchers at University of California San Diego, with colleagues at the Salk Institute of Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights into the underlying neurobiology of the human social brain.

In this study, the researchers used molecular, cell biological, in vivo genetic and bioinformatics approaches to identify the EGFR ligand amphiregulin as a physiological substrate, and demonstrate a role for iRhoms in amphiregulin - EGFR - dependent wound healing.

«It combines knowledge from the field of microfluidics, which uses fluids at a microscopic scale to miniaturize biological experiments, with the cellular, biological and molecular studies we conduct in laboratories.»

Other researchers on the study were Ahmet Denli, Christopher Benner, Thomas Lazzarini, and Apuã Paquola of the Salk Institute for Biological Studies; Jason Nathanson and Gene Yeo of the University of California San Diego, Department of Cellular and Molecular Medicine; Keval Desai of the University of California San Diego, Division of Biological Sciences; Roberto Herai and Alysson Muotri of the University of California San Diego, School of Medicine; Matthew Weitzman of the Department of Pathology and Laboratory Medicine at the University of Pennsylvania Perelman School of Medicine; and senior and corresponding author Fred H. Gage of the Salk Institute and Center for Academic Research and Training in Anthropogeny.

The EMBL team hadn't — and the EMBL spokesperson acknowledges that no one thought to do so: «We did not consider this an issue exactly because of the notoriety of the cells, and the existence of so much molecular biological and genetic data on these long before our study.»

Future studies should examine the possibility that there may be biological differences in the molecular mechanisms through which testosterone affects brain and behavior in men and women.

American Association for the Advancement of Science American Association of Anatomists American Association for Dental Research American Association of Immunologists American Astronomical Society American Economic Association American Educational Research Association American Geophysical Union American Institute of Biological Sciences American Mathematical Society American Physiological Society American Society of Agronomy American Society for Biochemistry and Molecular Biology American Society for Engineering Education American Society for Investigative Pathology American Society of Mammalogists American Society of Mechanical Engineers American Society for Microbiology American Society of Plant Biologists American Sociological Association American Statistical Association Association of American Geographers Association of American Medical Colleges Association of Biomolecular Resource Facilities Association for Molecular Pathology Association of Population Centers Association for Women in Mathematics Association for Women in Science Biophysical Society Coastal and Estuarine Research Federation Consortium of Social Science Associations Council of Energy Research and Education Leaders Council of Environmental Deans and Directors Crop Science Society of America Ecological Society of America Federation of American Societies for Experimental Biology Genetics Society of America Geological Society of America Institute of Electrical and Electronics Engineers - USA Mathematical Association of America National Council for Science and the Environment National Postdoctoral Association Population Association of America Research!America The American Federation for Medical Research The Biomedical Engineering Society The Endocrine Society The Optical Society The Ornithological Council Society for Neuroscience Society for the Study of Reproduction Soil Science Society of America SPIE, the international society for optics and photonics

«My preconceived notions of the limitations of DNA have been consistently shattered by our new advances in DNA nanotechnology,» said William Shih, Ph.D., who is co-author of the study and a Wyss Institute Founding Core Faculty member, as well as Associate Professor in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School and the Department of Cancer Biology at the Dana - Farber Cancer Institute.

biophysical approaches including single - molecule methods to study cellular machines (such as molecular motors) and fluid mechanics to study biological questions of cell morphology and tissue formation

«Rhinovirus C has been the «missing link» in explaining illness caused by the common cold,» says Michael Rossmann, Hanley Distinguished Professor of Biological Science at Purdue and co-lead of the study with UW — Madison's Ann Palmenberg, professor of biochemistry and with the Institute for Molecular Virology.

LA JOLLA, CA — A multi-institutional team headed by Ursula Bellugi, professor and director of the Laboratory for Cognitive Neuroscience at the Salk Institute for Biological Studies, has been awarded a $ 5.5 million Program Project Grant by the National Institute of Child Health and Human Development (NICHD) to link social behavior to its underlying neurobiological and molecular genetic basis using Williams syndrome as a model.

While studying biological sciences at Stanford I interacted with amazing scientists, such as Luis de Lecea, PhD, in whose laboratory I received my first hands - on experience in molecular neuroscience, and Robert Sapolsky, PhD, who was my advisor.

He joined the Division of Molecular and Cellular Biosciences (MCB) at the NSF after 4 years as a postdoctoral fellow at Harvard University and the Katholieke Universiteit in Leuven, Belgium, where he used brewer's yeast to study the biological function of highly mutable repetitive «junk» DNA sequences.

Studies on horizontal gene transfer and enzymemediated DNA rearrangements lead him to postulate a theory of molecular evolution according to which nature cares actively for the promotion of biological evolution by using products of specific evolution genes as well as several intrinsic non-genetic elements.

She received her degree in molecular biology from the University of California at San Diego and entered the Infectious Diseases Laboratory at La Jolla's Salk Institute for Biological Studies to analyze HIV integration mechanisms.

The goal of these integrated studies is to understand complex biological systems on a molecular level.

The main research focus of the single molecule group is the study of molecular motors, the role of force in regulating biological systems, and the molecular mechanisms of gene expression regulation.

Modern biophysics is a broad and rapidly advancing field encompassing the study of biological structures with a focus on mechanisms at the molecular, cellular, and systems level using the concepts and methods of physics, chemistry, mathematics, engineering, and computational science.

Spectroscopy & Application of Lasers, Zare / Moerner / +, 6 - 1 Nuclear Hormone Signaling, Chambon / Evans / Jensen, 6 - 1 Bioinorganic Chemistry, Gray / Lippard / Holm / — , 8 - 1 The Field (everything not listed), 10 - 1 Techniques in DNA Synthesis, Caruthers / Hood / +, 10 - 1 Electrochemistry / Electron Transfer, Bard / Hush / Gray / — , 19 - 1 Instrumentation / Techniques in Genomics, Venter / +, 19 - 1 Biological Membrane Vesicles, Rothman / Schekman / +, 19 - 1 Molecular Studies of Gene Recognition, Ptashne, 19 - 1 Organic Electronics, Tang / +, 39 - 1 Polymer Science, Matyjaszewski / Langer / + / — 69 - 1 Solar Cells, Grätzel / +, 74 - 1 Mechanistic Enzymology, Walsh / Stubbe / Koshland / + / — , 74 - 1 Combinatorial Chemistry / DOS, Schreiber / +, 99 - 1 Pigments of Life, Battersby / +, 99 - 1 Development of the Birth Control Pill, Djerassi, 99 - 1 Molecular Modeling and Assorted Applications, Karplus / Houk / Schleyer / Miller / + / — , 99 - 1 Applications of NMR Spectroscopy, Pines / Roberts / McConnell / + / — , 99 - 1 Development of Chemical Biology, Schultz / Schreiber / +, 99 - 1 Self - Assembly, Whitesides / Nuzzo / Stang / — , 149 - 1 Small Regulatory RNA, Ambros / Baulcombe / Ruvkun, 149 - 1 Nanotechnology, Lieber / Whitesides / Alivisatos / Mirkin / Seeman / + / — , 149 - 1 Eukaryotic RNA Polymerases, Roeder, 149 - 1 Contributions to Theoretical Physical Chemistry, Rice / +, 149 - 1 Mechanical Bonds and Applications, Sauvage / Stoddart / +, 149 - 1 Bio - & Organo - catalysis, List / Lerner / Barbas / + / — , 149 - 1 Organic Synthesis, Evans / Danishefsky / Nicolaou / Ley / Trost / Stork / Wender / Kishi / + / — , 199 - 1 Leptin, Coleman / Friedman / Leong, 199 - 1 Fluorocarbons, DuPont / Curran / — , 199 - 1 Understanding of Organic Stereochemistry, Mislow, 199 - 1 Tissue Engineering, Langer / +, 199 - 1 Contributions to Bioorganic Chemistry, Breslow / Eschenmoser / +, 199 - 1 Dendrimers, Frechet / Tomalia / +, 399 - 1 Zeolites, Flanigan, 399 - 1 Molecular Recognition, Dervan / +, 399 - 1 Molecular Machines, Stoddart / Tour / + / — , 399 - 1 Astrochemistry, Oka, 999 - 1

1 Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA 2 Integrative Genomics and Bioinformatics Core, Salk Institute for Biological Studies, La Jolla, CA, USA

Paul Sawchenko uses cell biological and genetic approaches in rodent models to study how stress - responsive systems are organized at a molecular level within the body and particularly within the brain.

Future studies of the Arabidopsis genome and the proteins it encodes (particularly those with no known function) will be greatly facilitated by combining the new DNA sequence information with a multitude of existing genetic and molecular biological strategies and resources that are available to Arabidopsis researchers.

Core NYCEP faculty at NYU are based in the Biological Anthropology section of the doctoral program in the Department of Anthropology, with an emphasis on research broadly related to the study of human evolution, molecular primatology and primate behavior.

To uncover molecular processes in individual cells and to understand the full complexity of biological systems, our lab applies and develops novel microscopy and genomics based techniques to study the regulation of gene - expression in single cells.

And speaking of those molecular and biological functions, that's exactly why cell culture studies are applicable to humans.

James L. Manley, Ph.D., a molecular biologist and Julian Clarence Levi Professor of Life Sciences in the Department of Biological Sciences at Columbia University is studying, together with his colleague Tsuyoshi Kashima, M.D., the basic biology of the SMN gene to find ways in which to recover its activity in patients.

Schosserer will be spending two months in the laboratory of Aric Rogers, Ph.D., at the MDI Biological Laboratory's Kathryn W. Davis Center for Regenerative Biology and Medicine studying the role that molecular regulators of gene expression play in longevity — and in particular how these regulators are affected by lower amounts of food or food with lower energy content.

Morphological, electrophysiological, biochemical, molecular biological and genetic studies related to psychiatric disorders in children and adolescents are welcome for publication.