Sentences with phrase «molecular circadian clock»

The molecular circadian clock coordinates the body's rhythms fine - tuned by environmental cues, such as light, to the 24 - hour solar cycle.

Not exact matches

The circadian clock is a molecular clock that is probably found in every body cell.

Understanding the molecular mechanisms of the circadian clock can be used to develop drug treatments, too, he added.

Tracking clock genes in hair follicles could help researchers better monitor patients with sleep disorders and other circadian rhythm dysfunction, says molecular biologist Ueli Schibler of the University of Geneva in Switzerland.

Early work in plants and insects had, in fact, established the existence of such body clocks, but it wasn't until the mid-1980s that the researchers, two of whom were collaborators, uncovered the inner molecular workings behind this basic process, called a circadian rhythm.

In an apparent ironic twist to this year's prize, the quarry claimed by countless hours of sleepless toil is itself fundamental to a good night's sleep: the molecular basis of circadian rhythms — those genes and proteins whose interactions underlie the ability of us living organisms to keep our internal body clocks entrained to a 24 - hour cycle.

Early work in plants and insects had, in fact, established the existence of such circadian clocks, but it wasn't until the mid-1980s that the researchers uncovered the inner molecular workings behind this basic process.

Mice lacking molecular - clock components (Per and Cry), or lacking Per genes in osteoblasts, display high bone mass, suggesting that bone remodeling may also be subject to circadian regulation.

Light sets the circadian rhythm by eliminating a key protein needed for the molecular mechanism of the body's clock, according to scientists in the March 22 issue of Science.

Currently we know very little about how our circadian clocks interact with viruses at the molecular level.

Circadian clock research has been ongoing for many decades and has led to the discovery of molecular mechanisms controlling the circadian rhythm, which was awarded the 2017 Nobel Prize in Physiology or Circadian clock research has been ongoing for many decades and has led to the discovery of molecular mechanisms controlling the circadian rhythm, which was awarded the 2017 Nobel Prize in Physiology or circadian rhythm, which was awarded the 2017 Nobel Prize in Physiology or Medicine.

He utilizes Drosophila genetics, bioinformatic (RNA - Seq, ChIP - Seq), and molecular genetic approaches to identify transcriptional regulators of circadian clocks and longevity.

Title: Nobel Prize Physiology 2017 (for their discoveries of molecular mechanisms controlling the circadian rhythm) is On Fiction as There Is No Molecular Mechanisms of Biological Clock Controlling the Circadiamolecular mechanisms controlling the circadian rhythm) is On Fiction as There Is No Molecular Mechanisms of Biological Clock Controlling the Circadiacircadian rhythm) is On Fiction as There Is No Molecular Mechanisms of Biological Clock Controlling the CircadiaMolecular Mechanisms of Biological Clock Controlling the CircadianCircadian Rhythm.

Molecular Dissection of Two Distinct Actions of Melatonin on the Suprachiasmatic Circadian Clock

It drives everything from sleep cycles to metabolism, but the inner - workings of this so - called «circadian clock» are complex, and the molecular processes behind it have long eluded scientists.

Within this broad topic we are particularly interested in characterising (i) the molecular mechanism by which these photoreceptors mediate light - dependent entrainment of the circadian clock, (ii) the components mediating, in a light - quality - dependent fashion, nucleocytoplasmic partitioning of phytochromes and UVR8, (iii) how phosphorylation and sumoylation of these photorecepors and other signalling components modulate red / far - red and UVB - induced signalling, and (iv) to what extent intercellular and cell - autonomous events contribute to phytochrome and UVR8 regulated photomorphogenesis.

We study how various physiological and molecular processes including physical activity, fat metabolism, circadian clocks, advanced glycation end products, calcification and intestinal permeability are influenced by nutrients to impact organismal health and survival.

Therefore, the description of the first genetic evidence linking the circadian clock system to energy regulation and metabolism provided a critical step forward for the field, enabling a flurry of biochemical, genetic, molecular, and physiologic studies capable of addressing the underlying mechanisms and pathways.