Sentences with phrase «molecular complexes»
"Molecular complexes" refers to a group of molecules that are interconnected and interact with each other in a specific way. They form a structure or unit that is larger than a single molecule and have unique properties or functions. Full definition
Molecular interactions on the millisecond time scale are very common, and single - molecule force spectroscopy of such short - lived molecular complexes requires sub-millisecond resolution and control of the applied load.
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Kelly and her team found that the BRCA1 protein forms a C shape, with molecular complexes on either open end.
These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex (the proteins cadherin 23, protocadherin 15, myosin VIIA and harmonin), as required for the mechanoelectrical transduction apparatus of the hair bundle to function correctly.
Both changes, working in tandem, strengthened the effectiveness of the entire molecular complex in terms of activating human iNKT cells, Howell says.
Cells alert the immune system to the presence of infections by displaying molecular complexes made from bits of their own proteins and those of invading organisms
Chromosomes are molecular complexes built out of the genetic material DNA and proteins.
Although some approved cancer drugs and others in development interfere with the same protein cleanup process, known as the ubiquitin - proteasome system, disulfiram targets only a specific molecular complex within this machinery.
The protein composition of the junctional sarcoplasmic reticulum membrane encompassing the excitation - contraction coupling molecular complex (ECCMC) is extremely complicated.
«Achieving Reversible H2 / H + Interconversion at Room Temperature with Enzyme - Inspired Molecular Complexes: A Mechanistic Study.»
They are areas where very massive stars have recently formed, and many contain the uncondensed gas, dust, and molecular complexes commonly associated with ongoing star formation.
This is currently revolutionizing the field of molecular biology, revealing detailed structures of otherwise intractable molecular complexes that are at the heart of many biological processes.
Characterization of a tight molecular complex between integrin alpha6beta4 and laminin - 5 extracellular matrix.
In 2012, she and postdoctoral fellow Prashant Mali teamed up on CRISPR - Cas9, a molecular complex that bacteria use as a primitive immune system; other scientists had recently gotten it to cut specific locations on DNA floating in test tubes.
Professor Haino points out that the resulting polymer is not simply a molecule, but a molecular complex — a supermolecule.
If cells were infected with an influenza A mutant lacking NS1, they proceeded to produce large number of the molecular complexes required for RNAi, which include a protein called Argonaute that slices through the target gene.
This molecular complex then binds to the promoter region of a gene called Bmi1, an event that increases the expression of the gene.
«By exposing a crystalized form of the molecular complex to a high - intensity X-ray beam at the Australian Synchrotron, we were able to obtain a detailed 3 - D image of the molecular interplay between the invariant natural killer T cell receptor and AH10 - 7,» says corresponding author Jérôme Le Nours, a structural biologist with the Biomedicine Discovery Institute at Monash University in Australia.
In general, D - Glu binds with a molecular complex called UDP - MurNAc - L - Ala, but in this pathogenic microorganism, L - Glu bound with the complex mediated by one of the two genes they identified.
Liquid phases are a natural environment for many interesting processes in chemistry and biology, and short light pulses allow insights into electronic and structural dynamics of molecules and molecular complexes.
One gene set that stood out involved components of the spliceosome, the molecular complex that helps prepare messenger RNA (mRNA) transcripts for protein production by removing noncoding segments called introns.
Another technique, known as maternal spindle transfer, is being developed by Shoukhrat Mitalipov's group at Oregon Health & Science University and involves moving the spindle, a molecular complex of chromosomes and proteins, from the mother's unfertilized egg into an unfertilized egg from a donor.
For several disorders known to arise from mutations in any one of a few distinct genes, the corresponding protein products have been shown to participate in the same cellular pathway, molecular complex, or functional module.
«By exposing a crystallized form of the molecular complex to a high - intensity X-ray beam at the Australian Synchrotron,» Le Nours says, «we were able to obtain a detailed 3 - D image of the molecular interplay between the invariant natural killer T cell receptor and AH10 - 7.»
When a molecular bond is weak, however, the unbinding kinetics becomes rapid and application of such protocols during the short lifetime of the molecular complex becomes challenging.
In two years, Darst published the first low - resolution structures of E. coli RNA polymerase in combination with the sigma factor molecule that guides it to the correct starting place on the gene, a molecular complex called holoenzyme.
According to the Linus Pauling Institute, chlorophyll can form «molecular complexes with some chemicals known or suspected to cause cancer, and in doing so, may block carcinogenic effects.»