Sentences with phrase «molecular growth factors»
A new study finds that shining a low - power laser on damaged rat teeth activates molecular growth factors already present in the tissue.
https://www.scientificamerican.com/ Not exact matches
Similar to capsaicin, tumor necrosis factor is suspected to both induce and reduce cancer cell growth, and was shown to commit cells to survival when stimulating EGFR transactivation mechanisms, indicating that EGFR could act as a molecular switch determining the antiapoptotic effect of tumor necrosis factor (50).
The team found that connective - tissue cells adjacent to colon cancer stem cells secrete growth factors that activate a molecular pathway in other cells that is vital to maintaining stem - cell - like qualities.
There are several factors that may affect the growth of stem cells based on batch - to - batch media variation,» said Alysson Muotri, PhD, associate professor in the UC San Diego departments of Pediatrics and Cellular and Molecular Medicine.
Multiplexed genetic screening for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) gene rearrangements and subsequent biomarker - guided treatment is cost - effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small cell lung cancer (NSCLC) setting in the United States.
Molecular biologist Matt Kaeberlein of the University of Washington in Seattle says the results are in line with work from his lab showing that slight differences in growth conditions, the genetic makeup of the yeast or other factors can change the outcome of the experiment.
Researchers at the San Diego Supercomputer Center (SDSC) and the Moores Cancer Center at the University of California, San Diego, have described for the first time the molecular mechanism of cancer development caused by well - known «resistance» mutations in the gene called epidermal growth factor receptor (EGFR).
That discovery, reported January 12 in Nature Structural and Molecular Biology, positions them to target factors driving ALT - dependent cancer cell growth.
The study, called «Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patients.
They depend on other cells and growth factors that may or may not be present in a particular region of inflamed tissue, says Rocky Tuan, who directs the Center for Cellular and Molecular Engineering at the University of Pittsburgh School of Medicine.
The team suspected that yet another player, brain - derived neurotrophic growth factor (BDNF), was involved because it is the molecular key to TrkB's lock.
In 1995, I began graduate studies on signal transduction by growth factors and receptor tyrosine kinases in the laboratory of Graeme Guy at the Institute of Molecular and Cell Biology (IMCB) in Singapore, obtaining my PhD in 2000.
When Ralph Arlinghaus, a molecular biologist at the University of Texas MD Anderson Cancer Center in Houston, learned that growth factor — starved healthy cells release a protein called 24p3 that causes them to die, he wondered if leukemia cells also use the molecule to kill off their competition.
For years researchers have been developing molecular imaging techniques that visualize hormonally active breast cancer cells — specifically those testing positive for human epidermal growth factor receptor 2 (HER2).
Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte - macrophage colony stimulating factor.
One is the molecular identification of cell growth and differentiation factors, and their receptors that mimic embryonic developmental cues, and allow PSCs to differentiate into almost any mammalian cell type.
A major challenge for assessing driver mutations, such as epidermal growth factor receptor (EGFR) mutations, in advanced disease is the scarcity of suitable biopsy tissue for molecular testing.
Notably, we found «Protein processing in endoplasmic reticulum» and «PI3K - Akt signaling pathway» might be impaired in DACD pathogenesis, while Growth factor receptor - bound protein 2 might be a crucial protein as a molecular target of the neuroprotective effects of ZBPYR.
The current findings could provide important clues to determine the culture conditions for promoting the differentiation of primate ES cells into mature gametes, and to understand molecular mechanisms of primate gametogenesis including the timing of germ cell induction, the regulation of germ cell gene expression, and the response to growth factors for germ cell differentiation.
Increased perfusion to brain tissue, decreased body weight, upregulation of growth factors and improved synaptic plasticity may all be molecular mechanisms underlying the benefits of enrichment and activity therapies.