Sentences with phrase «molecular level understanding»

In addition these studies allow us to obtain molecular level understanding of interactions of biomolecules with hydrophilic and hydrophobic surfaces in living systems.

Therefore a molecular level understanding of the dynamics is vital to designing functional selective drugs for GPCRs.

At postgraduate level, I wanted to go deep into the cellular and molecular level understanding of clinical research problems from computational perspective.

Not exact matches

«I do think the science is becoming mature enough that we are starting to understand really at a molecular level how a lot of these diseases are caused,» Fontoura said.

«The fundamental purpose of our research is to understand athletes at the molecular level,» Shane explained.

There is a paradox at the heart of much of the new research on early adversity and child development: While the problems that accompany poverty may be best understood on the molecular level, the solutions are not.

Understanding molecular structure at a theoretical level is perhaps interesting, but continually producing new chemicals (which we could only identify because the book told us how to) meant almost nothing.

As the researchers understand incompatibilities between butterflies on a molecular level, they plan to track how these creatures evolve and develop certain enzymes and proteins to solve this tug of war.

The researchers hope these study findings will aid in understanding the complex human reproductive cycle and the occasional problems that originate on a molecular level.

We have so much more biology to understand when it comes to immunotherapy and patient response at a molecular level.»

CCG will be «squeezing» more clinically meaningful information out of cancer genomics, to understand at the molecular level how genes and mutations drive cancer and determine response to treatment.

One way to do that is to provide a much greater granularity of understanding of the changes at the molecular level.

Visualizing cellular components and processes at the molecular level is important for understanding the basis of any biological activity.

«Understanding how the enzyme actually works requires the knowledge of its three dimensional molecular structure at the atomic level,» said Dr. Mueller, principal investigator for the study that used cryo - electron microscopy (cryo - EM) to reveal the enzyme at near atomic resolution.

«While rodents are essential for understanding mechanisms at a cellular or molecular level, at a higher cognitive level, the best you could do was a sort of rough analogy.

And once I got into brain biology, it became clear you needed to study the brain on the cellular level, and once you began to understand aspects of behavior in the cellular level, you wanted to understand the molecular level.

Functional genomics will also help scientists understand how AMF interact with their plant symbionts at the molecular level.

Clinicians are well - versed with the human body and the delicate use of surgeries and drugs, while scientists understand the intricacies of how the body functions at the molecular and cellular level,» he explains.

«Our study is a nice example of how the understanding of a disease on the molecular and cellular level results in new therapeutic options.

«Increasingly in the life sciences, developments are based on an understanding of processes at the molecular level, even where the molecules are large and in complex systems,» says Ashmore, «so an increased hiring of folk with a thorough understanding of the fundamentals is taking place.»

Precision medicine requires a deep and functional understanding, at a molecular level, of the drivers of healthy and disease - forming microbiota.

«We're looking forward to many exciting applications that will help scientists in computational chemistry and biophysics understand and predict the behavior of molecular systems at a fundamental level.»

The Mayo team has long sought to understand ATC at a molecular level to find treatments that offer longer survival.

Nair stressed that the focus of this study wasn't on developing recommendations, but rather on understanding how exercise helps at the molecular level.

Schweitzer believes understanding preservation at a molecular level could help paleontologists find traces of ancient life on Earth, as well as on planets like Mars.

«We hope that we can understand the processes at cellular and molecular levels by studying the fish brain,» he adds.

Ibáñez considers that «this result confirms the need to dedicate more resources to basic research that advances knowledge of biological systems at the molecular level, in order to understand them better and thus be able to resolve the problems that arise in patients.»

A new approach has been to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on this knowledge.

«This calls for a systems level approach, and network analysis techniques, to really understand how normal cells are transformed into cancer cells at the molecular level.»

These questions have to be answered to better understand the processes of life on the molecular level.

In a discovery that advances the understanding of how marijuana works in the human body, an international group of scientists, including those from the Florida campus of The Scripps Research Institute (TSRI), have for the first time created a three - dimensional atomic - level image of the molecular structure activated by tetrahydrocannabinol (THC), the active chemical in marijuana.

On the diamond jubilee of the double helix, we should admit that we don't fully understand how evolution works at the molecular level

«Understanding how these two developmental processes are coordinated at the molecular level is extremely challenging.

First is a systems level, to understand how biological and molecular processes are integrated and affect each other.

Although most of the biophysical constraints have been understood at the level of individual genetic regulatory elements, the researchers find that crosstalk is special: while it originates locally due to biophysical limits to molecular recognition, its cumulative effect only emerges globally.

This study provides experimental evidence which shows the important role of RNA levels in the controlling the fate of embryonic stem cells, and shows an understanding of RNA's ability to differentiate stem cells at the molecular level.

«We were able to understand why, at a molecular level, this failure in development takes place.»

Future oncologists will need to have a much deeper understanding of tumor biology on a molecular level than their predecessors.

«Seeing this helicase enzyme prepare to surround and unwind the DNA at the molecular level helps us understand the most fundamental process of life and how that process might go wrong.

«If we could predict the final 3D structures of proteins from their genetic sequence, we would be one step closer to understanding the cell on a molecular level and curing disease,» says co-author Gevorg Grigoryan, an assistant professor of computer science at Dartmouth.

While the connection between Down syndrome — one of the most common genetic conditions — and peripheral nervous system disease has been known for some time, the phenomenon has not been understood at the molecular and cellular level.

«Now, we need to better understand how this works at the molecular level so we can perhaps design therapeutics to prevent phosphorylation of that site.»

Scientists do not yet fully understand how antibiotics work on the molecular level, but they think that the drugs are effective in part by introducing reactive oxygen to bacterial cells, which damages key cellular structures.

Led by Professor David Roper at Warwick's School of Life Sciences and Dr Luiz Pedro Carvalho from The Francis Crick Institute, a paper published today in Nature Communications reveals a deeper understanding of how the antibiotic D - cycloserine uniquely works at a molecular level.

This has important implications for understanding macular degeneration at the molecular level, as well as for designing improved treatments for the disease.

For example, if we can better understand DNA at an atomic and molecular level, that will help us fine - tune and tailor health care according to patients» needs.

In essence, we are beginning to link molecular and macroscopic levels of analysis to better understand the diversity and complexity of autism.»

At the mechanistic level we try to understand the machinery as enzymes and little molecular machines, trying to see how we can manipulate them the best and push them a little bit one way or another.

Laboratory and field research is needed to refine gene drive mechanisms and better understand how gene drives work, from the molecular level through species and ecosystem levels.

From a therapeutic perspective, the goal of the work is to understand at the molecular level how axons degenerate, and block those pathways in patients to preserve nervous system function.