Researchers from the University of Illinois at Chicago and Yale University recruited 116 women who had lost at least two early pregnancies, and tested their levels of nCyclinE,
a molecular marker for endometrial health.
The gene is an important
molecular marker for AML stratification, and is frequently mutated in about 35 % of AML patients at diagnosis.
Lane 4:
Molecular marker.
Lanes: M, DNA
molecular marker; 1 - iPSC1; 2 - iPSC2; 3 - iPSC3; 4 - NSCs (negative control); 5 - probe 25 ρg; 6 - probe 50 ρg; 7 - 100 ρg; 8 - 200 ρg and 9 - 50 ηg.
Last year saw publications in Nature Genetics by Miotto and colleagues about multiple strains of artemisinin - resistant parasites in Cambodia, and in Nature by Dr. Frédéric Ariey and colleagues from Institut Pasteur identifying
a molecular marker of artemisinin resistance.
A molecular marker of artimesinin - resistant Plasmodium falciparum malaria.
Importantly, these mutations could serve as
a molecular marker for large - scale surveillance efforts to contain artemisinin drug resistance in Southeast Asia.
Taken together, these findings suggest that mutations in the K13 - propeller play an important role in determining artemisinin resistance, act as
a molecular marker for artemisinin - resistant parasites, and provide important clues into how resistance is developing in parasite populations in Southeast Asia.
Over the past years, we have built innovative methods, using deep learning and artificial intelligence to design and evaluate optimal breeding strategies from phenotypic,
molecular marker and whole - genome data.
This means that the materials are usually non-adapted (exotic or semi-exotic), but their desirable traits can be used in crosses, genetic studies,
molecular marker development and parent - building.
Large - scale resequencing of the first ESTs and subsequent genotyping of single nucleotide polymorphisms in large populations expanded the available
molecular marker resources and provided a basis for examining their association with traits of interest (Eckert et al. 2013).
«Initially, the cell identifies all potential replication origins with
a molecular marker.
To develop a model for generating the human colon, scientists first identified SATB2 (special AT - rich sequence - binding protein 2) as a definitive
molecular marker for hindgut in frogs, mice and in humans.
Moreover, combinations of multiple biophysical markers, such as stiffness and size, were about as good as the currently employed
molecular marker at classifying stem - like activity.
«
Molecular marker from pancreatic «juices» helps identify pancreatic cancer.»
That's your headline right there: «
Molecular Marker Corn Breeder known for Plant Sciences Software Development and Genomic Analysis.»
At Monsanto, the practice has become so common that, in a recent paper, the firm said «
molecular marker assisted breeding is becoming our conventional breeding process,» noting that many of its commercial crops are derived with the process.
This factor is the first lung
molecular marker during mouse and human development and is essential for lungs to mature properly in an embryo.
They found that women were five times as likely to develop cancer if they had a higher percentage of Ki67,
a molecular marker that identifies proliferating cells, in the cells that line the mammary ducts and milk - producing lobules.
The collaborative research team also found
a molecular marker that would help identify patients most likely to benefit from cabazitaxel treatment.
In healthy breast tissue, the percentage of cells expressing
molecular marker Ki67 (green) and p27 (red) was low.
However, the parasites also showed an increased susceptibility to mefloquine and completely lacked
the molecular marker for mefloquine resistance.
The researchers showed that the latest approach to epidemiology worked to track both HIV infections and levels of prostate - specific antigen,
a molecular marker associated with prostate cancer.
And the race is on to find
a molecular marker for PPQ resistance, the equivalent of the K13 gene.
Last year, his group found the hotly sought
molecular marker of artemisinin resistance, the Kelch 13 or K13 gene, enabling researchers to map its extent and spread in exquisite detail.
«Sea turtle crisis: Moisture, not just heat impacts sex of sea turtle hatchlings: Sex - ratio study first to use
molecular marker to explain why and how moisture affects the nest.»
Proceedings of COST SUSVAR / ECO-PB Workshop on organic plant breeding strategies and the use of
molecular markers, Driebergen, Netherlands, 17 - 19 January 2005.
(2005) Proceedings of the COST SUSVAR / ECO-PB Workshop on organic plant breeding strategies and the use of
molecular markers.
Lammerts van Bueren, E.T.; Backes, Gunter; de Vriend, H.C. and Østergård, H. (2010) The role of
molecular markers and marker assisted selection in breeding for organic agriculture.
In 2009, the American Thyroid Association (ATA) revised its guidelines to add that doctors may consider the use of
molecular markers when the initial biopsy is inconclusive.
The team looked for these cells in nonliving brain samples in two ways:
molecular markers that tag dividing cells and young nerve cells, and telltale shapes of newborn cells.
«Recognition of human receptors can serve as
molecular markers for the pandemic potential of the [isolated strains].»
On the scientific agenda are identifying
molecular markers for resistance, which would simplify testing; accelerating the development of alternative drugs; and studying the effectiveness of mass screening and treatment to eliminate malaria in the areas where resistance occurs.
Global gene expression studies found that the LPA - treated mice shared many similar
molecular markers as those found in humans with schizophrenia.
They can also track standard
molecular markers for mitochondria, nuclei, and other subcellular structures.
Researchers have been tracking the spread of artemisinin - resistant parasites first by looking for signs in patients, and later by using multiple mutations in the parasite's Kelch13, or K13, gene, as
molecular markers for resistance.
A chromosome - specific BAC library was used to assemble 82 % of the chromosome into 1036 contigs that were anchored with 1443
molecular markers, providing a major resource for genetic and genomic studies.
Fluorescence - activated cell sorters added the ability to separate cells into containers based on which
molecular markers they carry.
Based on anatomy and
molecular markers, we propose that it arose by duplication of a neighboring stem cell, which may have enabled finer neuronal control over leg - related behaviors, such as walking and grooming.»
Molecular markers — pieces of DNA that «mark» a specific gene — allow researchers to comb the genetic blueprint of a plant, match the sequence with a certain trait using computer programs, and develop seeds.
«Our data agree with the notion of high evolutionary rate - heterogeneity of
molecular markers in plants.
The pivotal
molecular markers that define the three tumor clusters — mutational status of the IDH1 and IDH2 genes and loss of chromosome arms 1p and 19q — are already routinely checked in clinical care, Verhaak noted, so implementing the new categories can be done relatively quickly.
Another student who was using phage - display technology to identify new
molecular markers in ovarian cancer attended a clinic in gynecologic oncology once a week throughout her dissertation research.
As it turns out, the answer to the question of whether it's possible to predict the usefulness of
molecular markers for phylogeographic studies is: it's not always this simple.
The biopsies come from patients diagnosed at the University Hospitals of Cruces and Basurto.The aim is «to find a combination of
molecular markers that will enable us to come up with the diagnosis and prognosis of the melanoma in the most effective way possible.»
Plant breeding research elsewhere in the world has benefited from advances in genomics and
molecular markers, but plant breeding scientists in China do not work closely with researchers in those areas, says Carl Pray, an agriculture, food, and resource economics expert at Rutgers University in New Brunswick, New Jersey, who has worked in China.
After extracting tiny amounts of ancient DNA from the mummies» bones, the researchers amplified 16 short tandem repeats (short sequences in the DNA that create a genetic fingerprint) and eight polymorphic microsatellites (hereditary
molecular markers) to testable quantities using techniques commonly employed in criminal or paternity investigations.
This could include measures such as CT scanning, cellular and
molecular markers taken from blood samples, sputum and exhaled air and microbiome anaylsis.
At the ASTMH meeting, scientists launched the Worldwide Antimalarial Resistance Network (WWARN), a global database that will collect information on resistance in vivo and in vitro, drug levels in patients» blood, and
molecular markers.
«Now that we have
molecular markers, we could sample the environment and find out which strains of the pathogen are out there.