Sentences with phrase «molecular markers»

"Molecular markers" are specific molecules found in living organisms that help scientists identify and track different traits or characteristics. These markers act like unique tags that can be used to study and understand genetic variations, diseases, or even identify individuals. Full definition
The researchers also identified molecular markers that should make identifying disease - causing strains easier in the future.
«To our knowledge, this is the first authentication study in cacao using molecular markers,» the researchers state.
This factor is the first lung molecular marker during mouse and human development and is essential for lungs to mature properly in an embryo.
They retain molecular markers that at the beginning of their existence helped guide their development.
As it turns out, the answer to the question of whether it's possible to predict the usefulness of molecular markers for phylogeographic studies is: it's not always this simple.
Building on existing clinical research at MD Anderson Cancer Center through collaborations and membership to the RNA Center to create a ncRNA - centric effort to drive discovery of molecular markers of cancer by evaluating, co-developing, facilitating and disseminating novel ncRNA technologies.
The favorable genes or alleles will be tagged with molecular markers for marker - assisted selection.
Researchers have been tracking the spread of artemisinin - resistant parasites first by looking for signs in patients, and later by using multiple mutations in the parasite's Kelch13, or K13, gene, as molecular markers for resistance.
They first classified different types of human corneal cells based on molecular markers, and then assessed their mechanical properties using atomic force microscopy.
«Our data agree with the notion of high evolutionary rate - heterogeneity of molecular markers in plants.
«For this project, we used SPLiT - seq to profile more than 150,000 cells in the developing mouse brain and spinal cord, and we defined many new molecular markers for specific cell type,» said Georg Seelig, a synthetic biologist at the Department of Electrical Engineering and the Paul G. Allen School of Computer Science and Engineering at the University of Washington.
They tested these samples for known molecular markers and for susceptibility to six antimalarial drugs.
In addition, histologic grading and the presence of specific molecular markers can also be useful in establishing prognosis, as well as in determining individual treatments.
Subdivisions of the adult zebrafish subpallium by molecular marker analysis.
Global gene expression studies found that the LPA - treated mice shared many similar molecular markers as those found in humans with schizophrenia.
«New predictive tool for assessing breast cancer risk: Levels of molecular marker Ki67 in healthy breast tissue predicts a woman's risk of developing breast cancer.»
Wealthy Romans and poor Romans ate similar grain - based diets, said Kristina Killgrove, an anthropologist at the University of West Florida, who has studied the diets of ancient Romans through molecular markers left in their teeth.
As well as identifying vital genes that orchestrate this transformation, the scientists discovered molecular markers that flag these Schwann cells as specialist repairers.
Based on the analyses employing molecular markers different authors concluded that wMel of D. melanogaster and wAu of D. simulans are closely related and both belong to the Wolbachia supergroup A [20]--[24].
In healthy breast tissue, the percentage of cells expressing molecular marker Ki67 (green) and p27 (red) was low.
Gene sequencing and molecular markers help track the best traits when breeding new crops.
Lanes: M, DNA molecular marker; 1 - iPSC1; 2 - iPSC2; 3 - iPSC3; 4 - NSCs (negative control); 5 - probe 25 ρg; 6 - probe 50 ρg; 7 - 100 ρg; 8 - 200 ρg and 9 - 50 ηg.
His research interests include active surveillance as a primary management option for patients with low - risk kidney cancers, and the molecular characterization of early metastatic potential in kidney and prostate cancers, including molecular marker discovery and elucidation of signaling pathways for therapeutic targeting.
They are the first to estimate sex ratios using a male - specific, transcriptional molecular marker Sox9, a marker of testis development in sea turtles and freshwater turtles.
In 2009, the American Thyroid Association (ATA) revised its guidelines to add that doctors may consider the use of molecular markers when the initial biopsy is inconclusive.
The I - SPY 2 Breast Cancer Clinical Trial, for example, a high - profile experiment aiming to test the use of certain molecular markers to guide cancer treatment, was designed to allow researchers to adapt the study's protocol in response to early results.
Last year, his group found the hotly sought molecular marker of artemisinin resistance, the Kelch 13 or K13 gene, enabling researchers to map its extent and spread in exquisite detail.
They can also track standard molecular markers for mitochondria, nuclei, and other subcellular structures.
Fluorescence - activated cell sorters added the ability to separate cells into containers based on which molecular markers they carry.
The pivotal molecular markers that define the three tumor clusters — mutational status of the IDH1 and IDH2 genes and loss of chromosome arms 1p and 19q — are already routinely checked in clinical care, Verhaak noted, so implementing the new categories can be done relatively quickly.
After extracting tiny amounts of ancient DNA from the mummies» bones, the researchers amplified 16 short tandem repeats (short sequences in the DNA that create a genetic fingerprint) and eight polymorphic microsatellites (hereditary molecular markers) to testable quantities using techniques commonly employed in criminal or paternity investigations.
This could include measures such as CT scanning, cellular and molecular markers taken from blood samples, sputum and exhaled air and microbiome anaylsis.
By attaching molecular markers to the protein and monitoring their orientation and position, we should be able to better understand communication between cells.»
At Monsanto, the practice has become so common that, in a recent paper, the firm said «molecular marker assisted breeding is becoming our conventional breeding process,» noting that many of its commercial crops are derived with the process.
That's your headline right there: «Molecular Marker Corn Breeder known for Plant Sciences Software Development and Genomic Analysis.»
Moreover, combinations of multiple biophysical markers, such as stiffness and size, were about as good as the currently employed molecular marker at classifying stem - like activity.
To develop a model for generating the human colon, scientists first identified SATB2 (special AT - rich sequence - binding protein 2) as a definitive molecular marker for hindgut in frogs, mice and in humans.
Using a system in which the exposure of mice to THS mimics that of human exposure in the homes of smokers, the researchers investigated the effects of THS exposure on biological molecular markers — or «biomarkers» — found in serum, and in liver and brain tissues.
Large - scale resequencing of the first ESTs and subsequent genotyping of single nucleotide polymorphisms in large populations expanded the available molecular marker resources and provided a basis for examining their association with traits of interest (Eckert et al. 2013).
This means that the materials are usually non-adapted (exotic or semi-exotic), but their desirable traits can be used in crosses, genetic studies, molecular marker development and parent - building.
The scientists did not, however, test molecular markers, such as telomere length or epigenetic changes.
«The benefit was most evident in patients with uninformative cytogenetic or molecular markers who had negative MRD [minimal residual disease] at the end of induction I.»
They identified gene expression profiles typical of different types of neurons, newborn neural progenitors and radial glia, as well as molecular markers differentiating oRGs and vRGs, which allowed the researchers to isolate these cells for further study.
To determine whether K13 - propeller mutations are a useful molecular marker in clinical settings, the team studied K13 - propeller mutations in patients from the Cambodian provinces of Pursat and Ratanakiri and for whom they knew the parasite clearance half - lives.
Therefore, mining associated molecular markers via association analysis might be a more powerful approach for identifying causative variation.
To hunt for possible molecular markers, researchers started with an African strain of P. falciparum parasites that had been repeatedly exposed to artemisinin until it was able to survive high doses of the drug in the lab.
The quest for molecular markers presents itself as a complex task, as Olivo explains: «There is evidence that artemisinin resistance has emerged on the Thai - Burmese border, as well as in western Cambodia; however, it is not clear whether these changes have a common origin.
With multiyear field studies, Xue identified plant traits related to drought tolerance, which can be used by breeders to develop drought - tolerant wheat cultivars and geneticists to screen molecular markers and speed the breeding process.
a b c d e f g h i j k l m n o p q r s t u v w x y z