The primary tumor location was an independent prognostic
marker in patients with RAS wild - type metastatic colorectal cancer after adjusting for age, gender, synchronous / metachronous disease, consensus
molecular subtype, and microsatellite instability and
molecular status, according to the results of an analysis (abstract 3503) of data from CALGB / SWOG 80405
presented at the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting.