Sentences with phrase «molecular mechanism of these changes»

Ultimately, we will determine the molecular mechanism of these changes.

Not exact matches

Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).

«Unless you «photograph» the changes that a protein undergoes and understand its movement and therefore the underlying molecular mechanism, this process is a mystery,» explains Laura Orellana, first author of the article.

However, many industry insiders say these changes are opening up unique opportunities for researchers who focus on translating basic science into real - world cures and are eager to explore the molecular mechanisms of disease, test hypotheses, and do work that benefits patients.

«It's not one big change in the genome of this fish, but lots of different molecular mechanisms used to achieve this amazing adaptation and speciation,» said Federica.

Isaiah Mansour, an undergraduate at the University of Maine, talks about how a Maine INBRE course on the molecular mechanisms of human disease at the MDI Biological Laboratory changed his life.

We aim to unravel the molecular mechanisms of the central nervous system's (CNS) response to neurovascular changes, with the ultimate goal to develop novel therapeutic strategies for neurological diseases.

«Future studies are focusing on the molecular mechanisms underlying the ageing - related changes in skeletal muscle and the specific effects of HRT on the structure and function of the dominant protein in skeletal muscle, called myosin, which generates force and movement.»

The next challenge for the team is to identify what might be some of the mechanisms at the molecular level driving these changes.

One of today's preeminent researchers on the molecular mechanisms of oxygen regulation, Dr. Semenza has led the field in uncovering how cells adapt to changing oxygen levels.

Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the cellular targets in the mucosa, in specific macrophages and DCs, to identify the possible pathways to invade the tissue and disseminate to other organs; iii) the involvement of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role of antibodies with different effector functions in changing the pathways of the virus.

«This work is a major step forward in understanding the molecular mechanisms that direct the changes in the chemical forms of plutonium,» said Dr. Andrew Felmy, a geochemist and lead author of the study.

Other molecular mechanisms linking the cloned 13.5 kb ws1 region to wing size evolution could also occur, including cis - regulation of prospero, changes in non-coding RNAs, or long - distance regulation of another gene.

To understand the mechanism of biological processes, time - resolved methodologies are required to investigate how functionality is linked to changes in molecular structure.

The main hypothesis includes a stress preconditioning response mechanism, in which it is believed that periods of nutrient deprivation displays a beneficial mild stress that results in molecular adaptive changes in various tissues, which increases the organism's resistance to bigger stressors such as excitotoxic and oxidative injury, including ischemia (33,71).

regardless of individual constituents (limited by density changes) Because, in all the transport processes the energy can move between transport mechanisms in the air by molecular collisions every few centimeters.

The crux of her current research focuses on the use of molecular fossils («biomarkers») and their isotopic composition to decipher mechanisms of (mass) extinctions, ecosystem response, and ecologic resilience during intervals of abrupt climate change.

Childhood sexual abuse and childhood physical abuse are among the strongest predictors of psychiatric pathology and severity of clinical course, including suicide.2,4 - 14 The influence of childhood sexual abuse and childhood physical abuse on psychological development is thought to be mediated directly by changes in cognitive processing of threatening stimuli,15 - 18 resulting in enhanced negative affect to daily life stressors.19 Although there is a clear link between early - life adversity and psychopathology, very little is known about the molecular mechanisms responsible for the long - lasting behavioral consequences of childhood abuse.