Sentences with phrase «molecular modeling process»

«Scientists develop a more effective molecular modeling process.»

Not exact matches

Using the nascent skin of the developing chicken embryo as a model system, we find that morphological and molecular symmetries are simultaneously broken by an emergent process of cellular self - organization.

The research approach is called multi-scale modeling or MSM, to reflect the ability to study disease processes at the molecular, cellular, and tissue levels as well as interactions occurring between the levels.

In this study, researchers constructed a mathematical model, based on ordinary differential equations, linking the different molecular processes associated with spine expansion together.

Using a rodent model of opiate addiction, Laviolette's team found that the process of opiate addiction and withdrawal triggered a switch between two molecular pathways in the amygdala controlling how opiate addiction memories were formed.

To study how and why DEB changes in volatility, the researchers measured properties such as vapor pressures and melting points, probed molecular structure, and ran quantum mechanical computer simulations to model the hydrogenation process.

Dr. Maria Iribarne, first author of this study, commented: «The gosh mutant is a good model for understanding the molecular and cellular mechanism of cone cell death and the pathological process of human LCA.

This machine learning technique builds a model that encodes the information contained in the database, and in turn this model can predict the outcome of the molecular self - assembly process with high accuracy.

Rigorous examination of this mammalian model is the first stage in figuring out molecular mechanisms that govern regenerative processes, which could have a significant impact on regenerative medicine for humans.

Notophthalmus viridescens, an urodelian amphibian, represents an excellent model organism to study regenerative processes, but mechanistic insights into molecular processes driving regeneration have been hindered by a paucity and poor annotation of coding nucleotide sequences.

A few species are studied as model organisms that can be used to gain knowledge of basic processes such as genetics, physiology, biochemistry, and molecular biology with results that are applicable to many organisms (Taylor et al., 1993).

Stubenhaus et al. propose that flatworms are useful models in which to study the molecular processes that are responsible for porphyrias in humans.

Her laboratory has successfully combined electrophysiological expertise with molecular and cell biology approaches to better understand complex mechanisms underlying the memory process in mouse models of AD.

«By developing this model system to explore the molecular underpinnings of regeneration, we now have a better understanding of the process.»

De novo rational design of molecular scaffolds mimicking protein interactions for specific interference in cell signaling processes: We apply molecular modelling and computer simulation techniques for designing molecules with pharmacological / biotechnological interest.

In patient samples and animal models, molecular biomarkers are used as indicators of normal and pathogenic processes.

This framework will be built upon available open - source deep learning platforms that can be adapted to address different aspects of the cancer process as represented by JDACS4C's challenge topics: 1) understand the molecular basis of key protein interactions; 2) develop predictive models for drug response; and 3) automate the extraction and analysis of information from millions of cancer patient records to determine optimal cancer treatment strategies.

memory process; hippocampo - cortical interactions; cholinergic system; glutamatergic system; Cellular and molecular biology; hippocampal neurogenesis; animal models of Alzheimer's disease; animal models of schizophrenia

The laboratory is also using chemical crosslinking - based structural mass spectrometry techniques coupled with molecular modeling to determine structures of large protein complexes and characterize protein conformational changes involved with physiological processes.

The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism, and other cellular processes as an ordered network of molecular transformations - an extended version of a classic metabolic map, in a single consistent data model.

in the short - term, further understand the molecular pathways involved in the process of oncogenic transformation in human hemopathies, using fine structural in vivo analysis of clinical materials, combined with the development of functional in vitro experimental systems and in vivo models of genetically modified mice;

Using these neurons, we can replay the disease process in a dish and use this as a model to study the molecular mechanisms involved.