«We're really trying to learn through
molecular profiling analysis and a lot of epigenetic changes how to beat cancer, but not beat the patient's brain in the process,» he says.
Not exact matches
Scientists performed an integrative transcriptomic
analysis, comparing gene expression networks across all three groups of participants and finding unique
molecular profiles and pathway enrichment patterns.
More specifically, we use large - scale data acquisition and quantitative modelling of phenotypes and
molecular profiles, systematic perturbations (such as drugs or high - throughput genetics) and computational
analysis of non-linear, epistatic interaction networks.
Many of our brain tumor clinical trials include
analysis of the
molecular profiles of patients» tumors.
Current explorations into the
molecular underpinnings of cell circuitry are leveraging multiple data types including expression
profiling and epigenetic
analysis leveraging RNA - seq and CHiP - Seq coupled with
molecular markers and cellular phenotypes.
In the next decade,
molecular research is going to further develop along five lines: predictive medicine, that investigates the genetic conditions predisposing to tumor risk; early
molecular diagnosis; the evaluation of each patient's prognosis based on his / her genetic
profile, in other words, the
analysis of what kind of mutation affects the DNA of altered cells; the investigation of the individual response to drugs, based on our genetic knowledge; «smart drugs», molecules able to hit the target in a selective way, killing only the deprogrammed cells.»
Omics are novel, comprehensive approaches for
analysis of complete genetic or
molecular profiles of humans and other organisms.
Recent advances in high - throughput
molecular and cellular
profiling tools, particularly genome - wide transcriptomic
analysis, offer the potential for unprecedented insights into the mechanisms underlying the acquisition of immunity.
Phylogenetic
analysis and expression
profiling of the pattern recognition receptors: Insights into
molecular recognition of invading pathogens in Manduca sexta
His team's
molecular analysis offered a general
profile of a person's lifestyle, but could not make a distinct match, like a fingerprint.