Sentences with phrase «molecular replacement»

This group crystallized the mouse JUNO protein and, as a result of X-ray crystal structure analysis, determined the crystal structure of JUNO by molecular replacement.

Topic: Extending the reach of molecular replacement in Phaser Presenter: Randy Read, Wellcome Trust Principal Research Fellow in the Department of Haematology at University of Cambridge.

The list of programs includes several with catchy names, such as beast (for molecular replacement), dimple (for ligand identification in difference maps), crank (for experimental phasing) and buccaneer (for model building), and some cryptic, such as seqwt and npo.

Topic: AMPLE: a pipeline for unconventional Molecular Replacement Presenter: Daniel Rigden, Ph.D., Reader in Post-Genome Bioinformatics, University of Liverpool, UK Host: Jason Key Recorded on April 26, 2016

For the computational structure approach, they relied on molecular replacement software implemented by SBGrid, generating a shell script to iteratively run hundreds of searches.

Improved molecular replacement by density - and energy - guided protein structure optimization.

«We could see water molecules and a belt of lipids around the protein, which was really transformative,» says Gonen, who also worked with Piotr Sliz to initiate the use of molecular replacement to phase electron diffraction data.

The system is automated and needs no user intervention when running a complicated combination of jobs, such as model searching, molecular replacement and refinement.

His group developed the wide - search molecular replacement portal (WS - MR), a tool that uses the Open Science Grid infrastructure to perform molecular replacement searches against all protein domains in the Protein Data Bank.

CNS includes Brunger's refinement methods, such as cross-validation and simulated annealing, as well as density modification methods and methods to obtain phase information by MAD phasing or molecular replacement.

Abbreviations: ASU, asymmetric unit; CMC, critical micellar concentration; CYMAL - 7, 7 - cyclohexyl -1-heptyl-β-D-maltoside; DDM, dodecyl maltoside; MAD, multi-wavelength anomalous dispersion; MR, molecular replacement; NDSB, non-detergent sulfobetaine; OMF, octyl maltoside fluorinated; pmf, protonmotive force; SeMet, selenomethionine; TDM, tridecyl maltoside; TM, transmembrane; UDM, undecyl maltoside