Research fields include translational research, invasion, metastasis, disseminated tumor cells, transcription, tumor - associated proteolysis, targeted therapy, micro-RNA,
molecular staging of cancer.
Not exact matches
Xiaoyuan Chen, Ph.D., Chief
of the Laboratory
of Molecular Imaging and Nanomedicine at NIBIB, and his team attempted to solve this problem by developing a radiotracer that could identify prostate
cancer at all
stages.
Co-author Subrata Sen, Ph.D., also a professor
of Molecular Translational Pathology, notes, «These findings are a significant advance considering that there's nothing else available now to detect early
stage pancreatic
cancer that has gone through blinded validations in multiple patient cohorts.»
«Adding these two biomarkers provided statistically significant improvement for all early
stage cancer versus healthy controls as well as other subcohorts when used with the current gold standard biomarker, CA 19 - 9,» said Ann Killary, Ph.D., professor
of Translational
Molecular Pathology.
«If we can define the boundaries
of molecular targets in saliva, then we can ask what the constituents in saliva are that can mark someone who has pre-diabetes or the early
stages of oral
cancer or pancreatic
cancer — and we can utilize this knowledge for personalized medicine,» said Dr. David Wong, a senior author
of the research and UCLA's Felix and Mildred Yip Endowed Professor in Dentistry.
«Cadherin - 22 could be a powerful prognostic marker for advanced
cancer stages and patient outcomes,» said lead author Prof. Jim Uniacke, Department
of Molecular and Cellular Biology.
«Although treatable at the early
stage, prostate
cancer is prone to metastasis,» explain the team
of authors, led by Xiaoyuan Chen, senior investigator, Laboratory
of Molecular Imaging and Nanomedicine at the U.S. National Institute
of Biomedical Imaging and Bioengineering.
The study sets the
stage for the development
of more - sensitive and specific non-invasive tests for prostate
cancer than those currently available, which could result in fewer unnecessary prostate biopsies with less treatment - related morbidity, according to a new study in The Journal
of Molecular Diagnostics.
SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider
of life science tools for translational research and
molecular diagnostic products, today announced the publication
of a landmark study in which Danish researchers used the Prosigna ® Breast
Cancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and
Cancer Assay risk
of recurrence (ROR) score to accurately predict rates
of 10 - year distant recurrence (DR)
of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and
cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early -
stage hormone receptor (HR)- positive, Her - 2 negative breast
cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and
cancer who received 5 years
of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.
Cancer hijacks the immune system by various cellular and molecular mechanisms and dysfunction of immune system arises during the early stages of cancer and throughout progression to later aggressive s
Cancer hijacks the immune system by various cellular and
molecular mechanisms and dysfunction
of immune system arises during the early
stages of cancer and throughout progression to later aggressive s
cancer and throughout progression to later aggressive
stages.