Sentences with phrase «molecular underpinnings»

Molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material.

Based on a modified version of Gottlieb's scheme of psychobiological development, this study conceptualizes epigenetic mechanisms as molecular underpinnings mediating interactions between neural and

Based on a modified version of Gottlieb's scheme of psychobiological development, this study conceptualizes epigenetic mechanisms as molecular underpinnings mediating interactions between neural and... genetic activity levels.

But in terms of the actual molecular underpinnings, there's far less predictability, and it's clear that there are many possible changes that can produce the same functional outcome.»

The researchers also dug into the potential molecular underpinnings of how the compounds interact to lead to this effect.

This finding is an important step towards a better understanding of the cellular and molecular underpinnings of addictive behavior, paving the way for the development of effective therapeutics.

But little is known about the molecular underpinnings of heroin addiction.

«Our goal here was to understand the molecular underpinnings of an important evolutionary transition, not to create a «dino - chicken» simply for the sake of it,» said Bhullar, lead author of the study, published online May 12 in the journal Evolution.

«Identifying the molecular underpinnings of why some individuals are at - risk for developing anxiety and depression has the potential to identify new treatment targets,» added Roseboom.

In addition to running his own lab, he directs the Applied Neurotherapeutic Research Group, a collaborative research initiative funded jointly by SFI and Wyeth, to understand the molecular underpinnings of changes in behavior and to identify new drug targets for diseases such as schizophrenia.

As a result, the emphasis in early development is on understanding the molecular underpinnings of disease and developing markers for therapeutic effects.

Lakshmi Devi, a neuroscientist and director of a lab studying the molecular underpinnings of drug abuse at Mount Sinai School of Medicine in New York City, began her research career studying a soil bacterium that grows on dead wood.

«Comparative genomics is a particularly attractive approach to reveal the molecular underpinnings of disease in inbred animals with the hope of gaining new insights into these diseases in dogs and humans,» says Ginns.

But, scientists have since identified that the five psychiatric disorders share a common genetic link and are now moving toward understanding the molecular underpinnings of psychiatric illness.

His research interests include the molecular underpinnings of cervical cancer (including developing genetic screens), the identification of the genetic determinants of quantitative traits in humans, and the application of massively parallel sequencing technology for understanding the genetics of complex disease.

«Those types of cartilage have different cellular constituents, so we would have to really investigate the molecular underpinnings regarding how these cells are regulated,» the researcher said.

The reason: The molecular underpinnings to its hearing are roughly the same as with people.

The effect on the molecular underpinnings of the fruit fly's ear are the same as experienced by humans, making the tests generally applicable to people, the researchers note.

But until now we did not understand the molecular underpinnings of feeding behaviour.»

To gain more insights into the effect's molecular underpinnings, Tingting Zhou and colleagues studied mice as they performed a standard social dominance test.

Fernández says they will now use a similar experimental setup to study the timing and molecular underpinnings of exercise and its influence on learning and memory in more detail.

Once the human and chimp genomes were deciphered about a decade ago, they realized they could now begin to pinpoint the molecular underpinnings of our big brain, bipedalism, varied diet, and other traits that have made our species so successful.

C.elegans has been used for decades as a model animal to study the genetic and molecular underpinnings of neurological disorders through a number of techniques including bio imaging, electrophysiology and behavior.

Like most academic institutions, today Scripps sticks mainly to basic research, discovering the molecular underpinnings of health and disease.

Katharina F. Heil loved her work studying the genetic and molecular underpinnings of Parkinson's disease.

In the late 1980s, Scheller and Südhof set out independently to unveil the molecular underpinnings of the process.

«APL develops when two tumor suppressors fuse together to become an oncogene,» adds co-author Pier Paolo Pandolfi, MD, PhD, Director of the Cancer Center at BIDMC whose own pioneering work revealed the molecular underpinnings of APL and led to its cure.

Ladd - Acosta's primary research interest is to understand the molecular underpinnings of autism.

During this year, the Diaz - Meco laboratory has further studied the molecular underpinnings of this critical pathway in cancer.

Systemic perspectives on the organism and organ level address fundamental questions of infection biology and shall contribute to reveal the molecular underpinnings of virus - induced immunopathologies and other inflammatory diseases.

This suggested that Zucchini was essential in piRNA biogenesis, however the molecular underpinnings of its mechanism were still unclear.

Current explorations into the molecular underpinnings of cell circuitry are leveraging multiple data types including expression profiling and epigenetic analysis leveraging RNA - seq and CHiP - Seq coupled with molecular markers and cellular phenotypes.

Zhang continues to apply his gift for molecular biology and penchant for neuroscience in studying the molecular underpinnings of neuropsychiatric diseases, hoping to identify novel therapeutic approaches.

«By developing this model system to explore the molecular underpinnings of regeneration, we now have a better understanding of the process.»

There, his focus turned from the mechanisms that enable T cells to distinguish self and foreign proteins to the molecular underpinnings of T cell development.

This approach targets the molecular underpinnings of cancer while leaving healthy cells unharmed.

So to be able to intervene and combat these diseases you need to understand the molecular underpinnings of this.

Magdalena Kalinowska is interested in understanding cellular and molecular underpinnings of neurodevelopmental disorders.

«Our goal here was to understand the molecular underpinnings of an important evolutionary transition, not to create a «dino - chicken» simply for the sake of it,» says Bhart - Anjan S. Bhullar in a news release.

Scientists at Boston Children's Hospital and Dana - Farber / Boston Children's Cancer and Blood Disorders Center are the international leaders in research into the molecular underpinnings and identification of different sub-types of CSA.

Scientists at Washington University in St. Louis reached a new milestone in cancer research this month with the completion of a comprehensive analysis of the molecular underpinnings of the causes of the disease.

The Noma laboratory seeks to determine evolutionarily conserved 3D genome - organizing mechanisms and their functions in the yeast model as well as in the human system, and also establish a clear mechanistic framework for understanding the molecular underpinnings for human cancers related to the disorganization of the cell nucleus.

Eric Lander, founding director of the Broad, said he hopes that better characterizing the molecular underpinnings of psychiatric diseases will finally give researchers the insights they need to start a revolution like the one that has occurred in cancer, where there are hundreds of drugs in development.