Sentences with phrase «molecular understanding of»

The opportunity now is that we've entered into an era of molecular understanding of improved physics and optics, we have an opportunity to think about newer, better ways to detect the disease, to figure out which patients are getting worse or are at risk of getting worse, to catch patients before they've lost vision and give them treatments.

Molecular understanding of the genes and pathways that modify blood lipid levels in humans will facilitate the design of new therapies for cardiovascular and metabolic disease.

Plant Cell Walls Throughout Evolution: Towards a Molecular Understanding of Their Design Principles, Purbasha Sarkar, Elena Bosneaga, Manfred Auer, Journal of Experimental Botany, 60 (13): pp. 3615 - 3635, Aug. 17, 2009.

Our blood analysis service is widely used in research to advance the molecular understanding of chronic disease development and improve prediction of disease onset.

Because untimely DNA replication can lead to unchecked cell division, these findings are crucial to a molecular understanding of cancer, a condition marked by runaway DNA replication.

Hypothesis driven approaches to vaccinology can utilise the knowledge gained from mechanistic mouse models and our molecular understanding of intrinsic defects to human cells.5 However, caution is required when extrapolating data from murine models, as there are substantial differences between immune ageing in mice and humans.6 Nevertheless, model systems and ex vivo analyses of molecular alterations in aged human cells have identified multiple changes in the vaccination response with age and the aged immune system in general.

Jeffrey Goldberg, MD, PhD, Bascom Palmer Eye Institute, University of Miami, observed that new opportunities for identifying glaucoma biomarkers have emerged thanks to advances in molecular understanding of the disease and in the fields of optics and physics.

Because of its critical importance for understanding the brain, its role in our capability to learn and to remember, and the many neurological and psychiatric disorders that involve synapses, a molecular understanding of chemical synaptic transmission has been one of the holy grails of neuroscience.

«This study expands our molecular understanding of C2c2 to guide RNA processing and provides the first application of this novel RNase,» said Doudna, who is also a Howard Hughes Medical Institute investigator.

Catalyst - driven processes are not the only thing that can be improved with a molecular understanding of silica - water adhesion.

Scientists study the germline of the roundworm Caenorhabditis elegans to identify the mechanisms that control stem cell proliferation and homeostasis, as well as to advance our molecular understanding of homologous signaling pathways humans.

Scientists have gained a better molecular understanding of the region of the brain in individuals with epilepsy which — due to a developmental abnormality, trauma, stroke, or a growing tumor — has stopped responding to control signals, and this results in recurrent seizures.

We need more genetic studies and a better molecular understanding of its generation, which could open unforeseen avenues to drug development.»

Examples of such «science» are the Copernican revolution, the atomic and molecular understanding of matter and the periodic table of elements, and the vastly enhanced image of the cosmos afforded by contemporaryastrophysics.

Not exact matches

Still, researchers now have a far better understanding of the molecular pathways in the ear and how to regenerate hair cells and repair synaptic connections.

«I do think the science is becoming mature enough that we are starting to understand really at a molecular level how a lot of these diseases are caused,» Fontoura said.

The candidate should have relevant clinical practice experience and an understanding of genetic concepts and molecular biology laboratory techniques.

Experience in orphan disease drug development and an understanding of genetic concepts and molecular biology laboratory techniques is beneficial.

Again, I note you didn't address the dishonesty of Strobel's book; whether quoting a direct misrepresentation from a non-scientist, or via a quote from someone who died long before molecular biology provided the basis for understanding how such transitions can occur, or via the earlier example of a clear quote mine.

Regarding Meyer's 2013 Darwin's Doubt: The Explosive Origin of Animal Life and the Case for Intelligent Design, paleontologist Donald Prothero asserts that Meyer, not a paleontologist nor a molecular biologist, does not understand these scientific disciplines, therefore he misinterprets, distorts and confuses the data, all for the purpose of promoting the «God of the gaps» argument.

When will molecular scientists finally understand the molecular make ups of mechanized brilliancies needs many operators and mechanics of such molecular machines?

Richard Dawkins, in his celebrated book, The Selfish Gene, exemplifies the same position.3 And a similar reduction of biology to a molecular science may be found in the writings of E.O. Wilson, Ernst Mayr, Jacques Monod and numerous other highly respected scientific writers.4 In Chance and Necessity, for example, Monod gives one of the most forceful renditions of the view that biochemical analysis is «obviously» the sole avenue to understanding the secret of life.5 Decades ago Jacques Loeb had already set forth the program of inquiry still emulated today by many biologists:

The molecular mechanisms providing «novel information» are well understood and these mechanisms have been directly tracked within real - time observations of speciation events.

A chair is composed of molecules, and it is molecular events, rather than the chair as a whole that can be understood as the unitary events that have subjectivity.

He is perhaps best understood as intending that the molecule can be treated as an enduring object (i.e., a serially - ordered society of actual occasions) by virtue of the fact that it contains a series of regnant molecular occasions.

It is possible to understand a great deal about mind by analyzing it in terms of its molecular basis.

The biological doctrine of evolution has also evolved since Darwin's day, being first transformed by classical genetics and later by molecular biology, with plenty of controversy still associated with the contemporary understanding of how evolution occurs.

«The fundamental purpose of our research is to understand athletes at the molecular level,» Shane explained.

There is a paradox at the heart of much of the new research on early adversity and child development: While the problems that accompany poverty may be best understood on the molecular level, the solutions are not.

As the researchers understand incompatibilities between butterflies on a molecular level, they plan to track how these creatures evolve and develop certain enzymes and proteins to solve this tug of war.

Rapid breakthroughs in genetic research, advances in molecular biology, and new reproductive technologies are enhancing our understanding of and responses to genetically inherited diseases.

«We need to have people who really understand the general technology,» says Melissa Kotterman, director and head of adeno - associated virus research at 4D Molecular Therapeutics (4DMT) in San Francisco, California, a company cofounded in 2012 by UC Berkeley bioengineer David Schaffer.

The new THSB unit includes a student edition with activities for 19 lessons but also a teacher edition, with instructions for carrying out all of the activities, molecular model kits, print and digital resources, and assessments for measuring student understanding.

Consequently, an in - depth understanding of the molecular workings holds hope for designing agents with just the desired properties that would act more precisely.

His research interests include the roles of zinc in proteins including zinc finger proteins, the mechanisms and systems biology of protein targeting to peroxisomes, and the development of detailed thermodynamic understanding of molecular recognition processes.

«We are in a scenario where we can collect massive amounts of genetic data using GWAS, but are realizing that does not provide the biological context we need in order to understand the results,» says Andy McCallion, Ph.D., assistant director of the human genetics graduate program and associate professor of molecular and comparative pathobiology at the Johns Hopkins University School of Medicine.

«What this implies is that the brain produces molecular signals that instruct the skeleton to form around it, although we understand relatively little about the precise nature of that patterning.»

«If we can understand the chemical complexity of these ices in the molecular cloud, and how they evolve during the formation of a star and its planets, then we can assess whether the building blocks of life should exist in every star system,» said Melissa McClure of the Universiteit van Amsterdam, the principal investigator on a research project to investigate cosmic ices.

CCG will be «squeezing» more clinically meaningful information out of cancer genomics, to understand at the molecular level how genes and mutations drive cancer and determine response to treatment.

In doing so, the team has provided a molecular dynamics tool that allows for the study of various heat transfer problems at the nanoscale, including understanding and utilizing passive liquid flows.

By exploiting new molecular and genetic insights, the research, done in collaboration with Pierre de Wit from Wageningen Agricultural University in the Netherlands, provides a better understanding of the defense system of crop plants against the damaging pathogens that grow in the spaces between plant cells.

«It is a big step toward understanding the molecular basis of host - virus interaction.»

«This is really the first time we've gone from risk variants highlighted by GWAS to a mechanistic and molecular understanding — right down to the nucleotide — of how a mutation can contribute to the risk of developing disease,» says Whitehead Founding Member Rudolf Jaenisch, who is also a professor of biology at MIT.

Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interrelationship of DNA, RNA and protein synthesis and learning how these interactions are regulated.

The central dogma of molecular biology where genetic material is transcribed into RNA and then translated into protein, despite being an oversimplified picture of molecular biology, still provides a good starting point for understanding the field.

Muotri's work is a nice demonstration of the power of mini-brains to help understand the early, cellular features of neurological disorders, says Madeline Lancaster at the MRC Laboratory of Molecular Biology in Cambridge, UK, who developed the organoid - growing method Muotri used.

«Understanding the molecular mechanism of the disease is the key to finding a treatment that works.»

One way to do that is to provide a much greater granularity of understanding of the changes at the molecular level.

A research team from Wayne State University recently published a paper in the Journal of Clinical Investigation that provides a paradigm shift in the understanding of cellular and molecular mechanisms underlying diabetic peripheral neuropathy (DPN) and wound healing in the treatment of corneal and skin diabetic ulcers.

By understanding the molecular logic of how those modules can be combined in different ways, we can begin to reconstruct how this diversity evolved.»