It's a common problem with
molecularly targeted cancer therapies, Shokat says.
Not exact matches
Currently, there are no
molecularly targeted therapies aimed at triple - negative breast
cancer, which is a type of
cancer negative for estrogen receptor, progesterone receptor and the HER2 protein — all key
targets for current
therapies.
Dr. Cole's research interests include
cancer genomics and the identification of
molecularly targeted therapies for pediatric malignancies.
The study suggests that pediatric brain
cancer patients may experience similar side effects of
molecularly targeted therapies, and may benefit from efforts to remediate any cognitive deficits.
Bottom Line: Young mice that received
molecularly targeted therapies used to treat brain
cancer in human patients sustained cognitive and behavioral deficits, but the deficits were largely reversible through environmental stimulation and physical exercise.
The study authors noted that the improved survival rates may come from changes in the management of advanced lung
cancer over the past two decades, including new chemotherapy agents and regimens, increased use of salvage chemotherapy and the introduction of
molecularly targeted therapies.