The researchers began by creating large membrane models with embedded and dyed channel proteins; they then put them on a glass surface and measured them using a single -
molecule measuring method known as fluorescence correlation spectroscopy.
Not exact matches
The
method uses two lasers to
measure the positions of opposite ends of a
molecule, or two different objects, based on the intensity of scattered light.
The new
measuring method makes use of a modified Atomic Force Microscope: a tiny ball glued to the cantilever of the microscope will attract protein
molecules.
The suggested
method is to use the Boltzmann constant, which is a
measure of the relationship between the kinetic energy of
molecules and temperature.
To this end, the scientists further developed a
method that has been used for many years to
measure distances within large
molecules.
The second
method involved
measuring the spread of air with water
molecules with different isotope composition in the layers with the compressed snow.
Currently, the
method is being used to assess the optical properties of photosynthetic antenna proteins in various states of assembly, and to
measure other protein - protein interactions at the single -
molecule level.
Researchers have developed a
method to directly detect and visualize individual biomolecules and their changing association states in solution by
measuring their size and charge characteristics while confined in a single -
molecule trap.
New developments in
methods made it possible to
measure a network of distances between the atoms in the protein
molecules that make up a fibril.
Twisting laser light offers the chance to probe the nano - scale: A new
method to sensitively
measure the structure of
molecules has been demonstrated by twisting laser light and aiming it at miniscule gold gratings to separate out wavelengths: April 5th, 2018
Scott D. Collins, Ph.D., University of Maine, Orono $ 850,000 (2 years) «High - speed Nanopore Gene Sequencing» Skilled in silicon fabrication
methods, this group will try to fabricate a nanopore with tiny electrodes and built - in circuits that will be used in experiments that attempt to
measure differences in the electron tunneling of individual nucleotides in DNA
molecules.
Also, the methodology allows
measuring biochemical reactions far from the surface, avoiding one of the main limitations of classic SM
methods, i.e., the need for immobilization of the
molecules under study on a surface (glass slide or microspheres).
Methods: Directly
measuring the amount of energy needed to split bonds inside a water
molecule when it hits an oxide surface was a major challenge.
«We
measured the spectrum of the planet using this
method at a wavelength range which is very sensitive to the spectral signature of water
molecules.»
Lubos's site explained why climate sensitivity is one degree, and (as I read him) his
method makes sense given the assumptions: he created a twin for each carbon dioxide
molecule in the atmosphere, with no other change, and
measured the difference in temperature.