But for people with type 2 or type 3 SMA, «the reality is that any sort of treatment would be a blessing,» says Jill Jarecki, research director of Families of SMA who, in a previous job, led the small -
molecule screening effort that yielded RG3039, the Repligen compound.
Not exact matches
«We've now shown that our method is a powerful way to identify antibiotics from natural products and understand how they work before they are ever purified,» she added, «potentially shaving years off of
screening efforts by identifying which organisms and growth conditions produce interesting bioactive
molecules.»
As part of the global
effort toward malaria eradication, phenotypic whole - cell
screening revealed the 2 - aminopyridine class of small
molecules as a good starting point to develop new antimalarial drugs.
The two labs combined
efforts to
screen hundreds of potential
molecules for ULK1 inhibition, narrowing the list down to a few dozen, and eventually one.