Sentences with phrase «molecules as probes»

Schreiber is a world leader in chemistry, using small molecules as probes in uncovering biological functions.

The prize, considered among the most prestigious in the scientific community, recognizes Schreiber for his work in chemical biology and for the use of small molecules as probes to uncover novel cellular mechanisms at the root of human health and disease.

Not exact matches

They are very important in medicine — most medications available now are small molecules — as well as in biology as probes to uncover the inner workings of cells and tissues.

And planetary probes have uncovered organic molecules in the atmospheres of Jupiter, Saturn, and Saturn's giant moon Titan, as well as amino acids in meteorites.

We demonstrate that the electron beam, simultaneously acting as an imaging probe and a source of energy to drive chemical transformations, offers a new tool for studying the chemical reactions of individual molecules with atomic resolution, which is vital for the discovery of new reaction mechanisms and more efficient future synthesis.»

«Characterizing the optical properties of as many naturally occurring molecules as possible to build a library of potential intrinsic luminescent sensors and edible probes to monitor quality in foods and pharmaceuticals,» said Ludescher.

A team of researchers from National University of Singapore (NUS) have created the first two - photon, small molecule fluorogenic probe that can serve as a useful tool for the rapid assessment of an individual's potential risk for Parkinson's disease.

The high MAO - B activity consistently observed in patients with Parkinson's disease has been proposed as a biomarker, but there has been a lack of suitable small molecule probes for MAO - B specific detection in live cells and tissues.

«A carbon monoxide molecule adsorbed onto the tip of the AFM «needle» leaves a single oxygen atom as the probe,» Fischer explains.

As instrumentation and observation techniques have become more sophisticated over the past few years, exoplanet researchers have begun probing the nature of these bodies more deeply, even identifying specific molecules in their atmospheres.

The researchers inserted molecules of the amino acid tryptophan into the protein as a probe, and measured how water moved around it.

As you get even denser clouds, the carbon binds to oxygen creating carbon monoxide molecules — and at that point you can probe the cloud conditions that precede the collapse into a star.»

Researchers have used this strategy to probe how cells react to the sudden release of signalling molecules, such as the neurotransmitter glutamate and calcium ions.

He then began applying his expertise in microwaves to spectroscopy, which he foresaw as providing powerful new tools for probing the structure of atoms and molecules and for controlling light.

The researchers then used a dynamic force - scanning probe microscope for single - molecule force spectroscopy as well as antibody - recognition force microscopy (Ig - RFM) to map the locations of MtrC and OmcA on the surface of live Shewanella cells.

Trained as a physicist, I found my way through optical physics, nanotechnology, and biophysics to learn how to visualize the arrangement and the interaction of molecules at the nanometer scale and how to probe and manipulate them.

The study, which appears as a Nature Chemical Biology Advance Online Publication on March 28, 2016, began as an effort in the Cravatt laboratory to discover and characterize new serine / threonine hydrolases using fluorophosphonate (FP) probes — molecules that selectively bind and, in effect, label the active sites of these enzymes.

The Unit's scientific mission covers the design, synthesis, molecular modeling, as well as biophysical, biochemical and cellular studies of small - molecule probes and drug candidates targeting nucleic acids or proteins involved in cancer.

Modified genes, expression vectors, probes, modified proteins, monoclonal antibodies and receptors, cells and other chemical compounds such as small organic molecules are patentable.