The disease itself is painless but affected dogs should be regularly
monitored by an ophthalmologist to treat possible secondary effects of PRA (the most widespread form of PRA across dog breeds) IG - PRA1 first presents as a loss of vision in dim light conditions due to degeneration of rod cells in the retina.
It is unknown whether iris cysts cause GRPU, whether GRPU cause iris cysts, or whether iris cysts are unrelated entirely to GRPU.2 As mentioned earlier, iris cysts in a Golden Retriever are a «red flag» and a risk factor for GRPU, and these dogs must be very carefully examined and regularly
monitored by an ophthalmologist for the presence of GRPU.