Not exact matches
Rhesus
monkeys injected with the VLPs produced antibodies that gave them complete protection
against the
virus.
A molecule naturally produced by the immune system protects mice and
monkeys against Zika
virus infection, an international team of researchers has found.
Researchers for the past decade have focused on the T cell approach, based on studies showing that
monkeys receiving such vaccines
against simian immunodeficiency
virus, related to HIV, lived longer or had lower viral levels than usual.
«Previously, we demonstrated that ZPIV protected mice and
monkeys against Zika
virus.»
-- Hyperimmune globulin, prepared by purifying and concentrating plasma of immunized animals or previously infected humans with high titers (concentrations) of neutralizing antibody
against Ebola
virus, which have been shown to be protective in
monkeys but are not currently available and would not be expected before mid-2015.
Tests in macaque
monkeys also showed that a single vaccine dose of only 50 micrograms provided strong protection
against exposure to Zika
virus five weeks later.
GOOD SHOT A test vaccine given to camels and
monkeys gins up immunity
against the MERS
virus (shown here in a colorized micrograph).
Rhesus
monkey TRIM5α protects
against HIV - 1, but the only modern
virus that the human protein has any effect on is one that causes leukemia in mice — which happens to be closely related to PtERV1.
One anticoagulant that Geisbert helped test
against the
virus was greeted with great enthusiasm when he presented results 7 years ago, because it was the first time a drug had much impact — and yet it only reduced deaths in
monkeys by one - third.
In a previously published paper, Barouch and colleagues, including Colonel Nelson L. Michael, MD, PhD, director of the Military HIV Research Program at the Walter Reed Army Institute of Research (WRAIR) and Stephen Thomas, MD, Upstate Medical University, State University of New York, demonstrated that three different vaccine candidates provided robust protection
against Zika
virus in both mice and rhesus
monkeys.
Infection researchers from the German Primate Center (DPZ)-- Leibniz Institute for Primate Research have in cooperation with international colleagues tested a new vaccination strategy
against the HIV - related simian immunodeficiency
virus (SIV) in rhesus
monkeys.
A VACCINE
against Zika
virus has given mice and
monkeys immunity in tests.
The investigators found that the immunized
monkeys mounted antibody responses
against diverse strains of HIV and the
monkeys also mounted cellular immune responses to multiple regions of the
virus.
An earlier preclinical study found that rhesus
monkeys that were vaccinated with ZPIV developed a strong immune response and were protected
against two strains of Zika
virus.
Protective efficacy of multiple vaccine platforms
against Zika
virus challenge in rhesus
monkeys.
2012 — Novel Ad26MVA vaccine provides protection
against SIV — Results found Ad26 / MVA vaccine combinations can provide partial protection
against infection by Simian Immunodeficiency
Virus (SIV) in rhesus
monkeys.
Reporting in Nature Medicine this week, Philip Johnson, a professor of pediatrics at the University of Pennsylvania, in Philadelphia, and his colleagues managed to protect
monkeys from infection with the simian immunodeficiency
virus (SIV), the animal model that is closest to HIV, by shuttling a gene into their muscles that produces antibody - like molecules that work
against SIV.
Results from a recent study show that novel vaccine combinations can provide partial protection
against infection by Simian Immunodeficiency
Virus (SIV) in rhesus
monkeys.
A research article published in the journal Science has reported the efficacy of three different vaccine platforms
against the Zika
virus in rhesus macaque
monkeys.
So these data from
monkeys, Dudley says, suggest «that a vaccine could be quite effective
against the
virus.»
The new Ad26 / MVA and Ad35 / Ad26 vector - based vaccine regimens resulted in over 80 % reduction in the per - exposure probability of acquisition of infection
against repetitive challenges of SIV, a
virus similar to HIV that infects
monkeys.
When
monkeys and apes are infected with Zika, they develop antibodies
against the
virus in approximately 14 days.