Men with a variant may develop earlier and
more aggressive prostate cancer.
«These results suggest low levels of testosterone are associated with
more aggressive prostate cancer.
Depressed men with localized prostate cancer were more likely to be diagnosed with
more aggressive prostate cancer, received less effective treatments and survived for shorter times than prostate cancer patients who were not depressed, a UCLA study has found.
Eating a diet higher in saturated fat, a type of fat found commonly in foods such as fatty beef and cheese, was linked to
more aggressive prostate cancer, a study by University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators has found.
«Researchers find protein that may signal
more aggressive prostate cancers.»
Not exact matches
«Markers for
prostate cancer death can identify men in need of
more aggressive treatment.»
«This study demonstrates that targeted fusion - guided biopsy could significantly enhance our ability to identify patients with high - risk
prostate cancers that need
more aggressive treatment,» says lead author Mohummad Minhaj Siddiqui, MD, assistant professor of surgery at the University of Maryland School of Medicine and director of urologic robotic surgery at the University of Maryland Marlene and Stewart Greenebaum
Cancer Center.
«Why
prostate cancer is
more aggressive in obese patients.»
Even
more troubling, her study found a link between high blood levels of lycopene's chemical cousin, beta - carotene, and an increased risk of
aggressive prostate cancer — not enough to justify avoiding carrots and other food sources of beta - carotene but an ominous sign that not all food - derived compounds are necessarily benign when taken at higher doses.
«A
more complete Mediterranean diet may protect against
aggressive prostate cancer: New study in The Journal of Urology ® finds that a high intake of fruits, vegetables, and whole grains might not be enough.»
«This combination test is not designed to say definitively at diagnosis whether a man has
aggressive prostate cancer, but it can provide a
more accurate estimate of the likelihood of having
cancer and the likelihood of that
cancer being
aggressive,» Tomlins says.
Mi -
Prostate Score, or MiPS, was significantly more accurate than PSA alone for predicting cancer as well as predicting aggressive prostate cancer that is likely to grow and spread
Prostate Score, or MiPS, was significantly
more accurate than PSA alone for predicting
cancer as well as predicting
aggressive prostate cancer that is likely to grow and spread
prostate cancer that is likely to grow and spread quickly.
By age 80,
more than 50 percent of men will develop
prostate cancer but not all will have the
aggressive, deadly form of the disease.
UCLA researchers found that conventional «blind» biopsy failed to reveal the true extent of presumed low - risk
prostate cancers, and that when targeted biopsy was used,
more than a third of these men had
more aggressive cancers than they thought.
«For men with
prostate cancer, emotional distress may lead to
more aggressive treatment.»
Denmeade says the combination of drugs that block testosterone production and receptors, called androgen deprivation therapy, may make
prostate cancer more aggressive over time by enabling
prostate cancer cells to subvert attempts to block testosterone receptors.
«Emotional distress may motivate men with low - risk
prostate cancer to choose
more aggressive treatment, such as choosing surgery over active surveillance,» said UB's Heather Orom, the lead author on the study, published in the February issue of the Journal of Urology.
The authors stressed that the long - term reduction in
aggressive disease was observed only in men after
more than a year of testosterone use, and the risk of
prostate cancer did not differ between gels and other types of preparations.
The old idea that
cancer is less
aggressive in the elderly is not entirely without merit: breast and
prostate cancers tend to grow
more slowly in older patients.
«Metastatic
prostate cancer cases skyrocket:
More lax screening rather than more aggressive disease?.&ra
More lax screening rather than
more aggressive disease?.&ra
more aggressive disease?.»
Dr Hayley Luxton, lead researcher from the Molecular Diagnostics and Therapeutics Laboratory at University College London, said: «Using antibodies mounted with a toxic payload, we can exploit the fact that
aggressive prostate cancer cells have
more NAALADL2.
Similarly men with these gene variants were three times
more likely to be diagnosed with
aggressive prostate cancer (Gleason 8 or
more).
The researchers are now further investigating the possibility of using this approach on other
cancers, including
prostate cancer, where it could be used to distinguish
more aggressive tumors from those that grow much
more slowly, Bhatia says.
«What was most surprising was that patients who underwent
aggressive treatment for their
prostate cancer were
more likely to receive routine lab testing and visits with their doctor than those not receiving
aggressive treatment.
Furthermore, they found that D4A is
more effective than abiraterone at killing
aggressive prostate cancer cells, suggesting that some patients may benefit from direct treatment with D4A.
«Researcher discovers metabolite of
prostate cancer drug
more effective at treating
aggressive tumors.»
After following 154 men with low - risk
prostate cancer for 38 months, the investigators found that low levels of free testosterone were significantly linked with an increased risk of developing
more aggressive disease.
Like pervasive hypertension, some
cancers, such as
prostate and breast, tend to occur earlier and be
more aggressive in blacks than whites, said Dr. Edward J. Kruse, chief of surgical oncology at MCG and the Georgia
Cancer Center.
Men with BRCA1 / 2 mutations who develop
prostate cancer tend to develop these
cancers at an earlier age than average and may develop
more aggressive forms of the disease.
A new urine - based test improved
prostate cancer detection — including detecting
more aggressive forms of
prostate cancer — compared to traditional models based on
prostate serum antigen, or PSA, levels, a new study finds.
Men with these mutations are
more likely than non-carriers to contract
aggressive, lethal
prostate cancer, to be diagnosed at a
more advanced stage and to ultimately die of the disease, researchers say.
Mutations in the beta - catenin gene, or flaws in the factors that degrade it, have long been linked to
more aggressive disease in various tumor types, including colon, lung and
prostate cancer, and melanoma.
Carriers of germline mutations in BRCA2 have at least five times greater risk of
prostate cancer and frequently develop a
more aggressive form of the disease.
One of the SNPs is located on the X chromosome and the other SNP is located on chromosome 2p15 and is associated with a
more aggressive form of
prostate cancer.
Newly published research from Fred Hutch shows black men may be at heightened risk not only of developing
prostate cancer but also of having a
more aggressive form at a younger age.
A study was done in 2013 which proved that patients who had poor sleeping habits were much
more likely to develop an
aggressive form of
prostate cancer.
While men with the
more aggressive form of the
cancer make up about 5 % of the 180,000 to 200,000 cases of
prostate cancer in the U.S. each year, and only 12 % will have these mutations, that population is still at considerably higher risk of developing advanced disease.
In a report published in the New England Journal of Medicine, scientists say that a panel of 20 genes can distinguish the
more common localized
prostate cancer that grows slowly and rarely spreads from the
more aggressive type that can spread quickly.
The findings also hint that in coming years, it may be possible to use the panel not just among men with advanced disease but to distinguish between men who develop the slower growing type of
prostate cancer from the
more aggressive type.
The task force also calls for
more research in this area, including ongoing studies looking at the potential for MRI and genetic testing to better detect
aggressive prostate cancers, Krist added.
In the
Prostate Cancer Prevention Trial, a study involving more than 18,000 men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
Prostate Cancer Prevention Trial, a study involving more than 18,000 men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
Cancer Prevention Trial, a study involving
more than 18,000 men, subjects taking dutasteride had a lower rate of
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
cancer, but a significantly higher rate of
aggressive prostate cancers than the placeb
prostate cancers than the placebo group.
This resulted in a higher absolute number of
aggressive prostate cancers in the dutasteride group than in the placebo group — even though the placebo group had a higher rate of
prostate cancer.141 Thus, as we have seen elsewhere, e.g., rofecoxib (Vioxx ®), celecoxib (Celebrex ®), balance in biological processes is
more beneficial than absolute interruption.)
In the
Prostate Cancer Prevention Trial, a study involving more than eighteen thousand men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
Prostate Cancer Prevention Trial, a study involving more than eighteen thousand men, subjects taking dutasteride had a lower rate of prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
Cancer Prevention Trial, a study involving
more than eighteen thousand men, subjects taking dutasteride had a lower rate of
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placeb
prostate cancer, but a significantly higher rate of aggressive prostate cancers than the placebo
cancer, but a significantly higher rate of
aggressive prostate cancers than the placeb
prostate cancers than the placebo group.
This resulted in a higher absolute number of
aggressive prostate cancers in the dutasteride group than in the placebo group — even though the placebo group had a higher rate of
prostate cancer.145 (See above «Mechanisms through which 5α - reductase inhibitors promote
prostate cancer»)(Neal, please make this a link to this section above) Thus, as we have seen elsewhere, e.g., rofecoxib (Vioxx ®), celecoxib (Celebrex ®), balance in biological processes is
more beneficial than absolute interruption.)
Prostate cancer in dogs is much
more aggressive in humans and spreads rapidly.