Sentences with phrase «more cell damage»

Exposure to Alternaria produced more cell damage in the cells of the airway's lining.

Mice living in cages with these fabrics for up to six months had more cell damage in their liver and brain than mice who weren't exposed to this third - hand smoke.

By measuring levels of the stress hormone cortisol, plus other chemical markers, the team found that the task caused more cell damage in the women who were already stressed.

Not exact matches

«What we're trying to do is make your nerve cells more resistant to damage,» Ray said.

By discovering more about their survival tricks, the researchers hope to learn more ways to protect human cells from damage.

In other words, consuming more antioxidants seems to protect your cells from damage as well as enabling them to recover from exercise.

Theoretically, the more antioxidants you consume, the higher your chance of avoiding cell damage and circumventing the problems that can spring from it, such as cancers.

The key to matcha green tea's health benefits, EGCG protects cells from oxidative damage caused by free radicals; it provides even more antioxidant protection than vitamin C or E.

Plus, they contain large amounts of antioxidants, substances that protect cells from damage caused by oxidation.Chia seeds look... [Read more...]

Because the red blood cells are more prone to damage by oxidative substances in an individual with G6PD Deficiency, a diet rich in antioxidants is important.

One or more cells are then removed to check for chromosome damage.

Gravekamp thinks the radioactive bacteria affected metastatic tumours most because cells there were still rapidly multiplying, leaving their chromosomes more open to damage than those in healthy tissues or in the original tumour.

«There are currently no therapies which successfully reverse the damage seen in the more than 12,000 individuals who suffer a spinal cord injury each year in the United States alone,» says Dr. Richard G. Fessler, professor of neurological surgery at Rush University Medical Center and principal investigator for the Phase 1 clinical trial involving AST - OPC1 (oligodendrocyte progenitor cells).

When RCGD 423 was applied to joint cartilage cells in the laboratory, the cells proliferated more and died less, and when injected into the knees of rats with damaged cartilage, the animals could more effectively heal their injuries.

We know that they are under stress when they are fighting cancer or other diseases, so I wondered whether anything measureable could be seen if we put them under further stress with UVA light.We found that people with cancer have DNA which is more easily damaged by ultraviolet light than other people, so the test shows the sensitivity to damage of all the DNA — the genome — in a cell.»

These symptoms, whether mild or more severe, are generally caused by damaged brain cells.

The mechanisms that promote or enable drug resistance include drug inactivation, drug target alteration, drug removal from cells, DNA damage repair, cell death inhibition and the epithelial - mesenchymal transition (EMT) that enable solid tumors to transform into more metastatic grades.

Since cancer cells divide more often than most normal cells, they react more sensitive to DNA damaging agents.

And according to a third theory, as organisms age they deteriorate and must spend more energy to repair cell damage — to the detriment of other essential physical functions.

Until now, microglia have been dismissed as simple immune cells that do little more than protect brain cells from damage and tidy up in the aftermath of disease.

Unlike normal cells, however, the tumour cells are considerably more sensitive, because they can not repair damage well.

Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem cells and [the] like, it may be interesting to see if there are other ways, alternatives to dealing with really badly damaged hearts that would involve growing a new heart or replacing or repairing the damage d to a badly damaged heart that might make artificial hearts less important in the somewhat more distant future.

Brains of people who died from various diseases caused by tangled tau had more dead and damaged cells if the people carried APOE4.

If we introduced stem cells with nice, long telomeres in the first place, we could let them wind down and eventually be lost to apoptosis, senescence, or other sources of damage — and just top our tissues up with more stem cells before enough of those cells were lost to begin to impair tissue function.

The researchers found that mutant mice lacking Del - 1 had more severe attacks of the EAE than normal mice, with more damage to myelin, the fatty sheath that coats neurons and helps in the transmission of signals along the cell.

Under the microscope the chromosomes of the Werner cells showed more signs of damage than did the healthy counterparts.

Zinc is a particularly versatile player, involved in more than 300 enzymatic reactions; when zinc goes missing, a cell's DNA and its repair machinery can be damaged.

But more importantly, the research, using induced pluripotent stem cells, suggests the neuronal damage might be reversible through novel anti-inflammatory therapies.

«RYBP would make cancer cells more sensitive to DNA damage, which would make chemo or radiation therapy more effective,» said Mohammad Ali, a postdoctoral fellow and the lead author of the study.

Ali found that breast cancer cells that have high levels of RYBP are more sensitive to DNA damage after radiation or drug treatment, including PARP inhibitors (inhibitors of the enzyme poly ADP ribose polymerase used in cancer treatment).

«The last thing we need from a vaccine is more inflammatory damage,» says Shah, who has been working with Swedish cell biologist Jan Nilsson on a vaccine that boosts the antibodies responsible for gentle plaque removal while damping vessel - damaging inflammation.

But even more far - ranging treatments may be possible with embryonic stem cells, the blank - slate cells that give rise to all organs and tissue types and that (theoretically) can repair all forms of organic damage and disease.

Understanding the coordinated development of motor neurons and glia may inform ways to prod stem cells into generating more glia after someone suffers an injury with nerve damage.

Second, older cells are more vulnerable to this damage — or less able to repair themselves.

One of them was used to reproduce acquired aplastic anemia: due to various types of damage, some of the stem cells die, and those that remain need to divide more frequently in order to maintain the production of blood cells; as a result of so many divisions, the telomeres shorten and the disease appears.

Comparing the damaged sites in normal cells before and after infection with H. pylori revealed that genes located close to the margins of the chromosomes, the so - called sub-telomeric regions, are more likely to be damaged after infection, as are genes that are active in gastric cells.

But after high - dose damage, too many cells would have double - strand breaks to replace them all, and repair would make more sense.

«This gentle laser didn't burn the skin or damage tissue, so it could be dosed multiple times and more thoroughly stop the cancer cells from being able to travel,» said researcher Ronghu Wu.

Rather than artificially triggering cancer by engineering genetic mutations, this model more closely mimics human liver cancer in that tumors develop as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic disorder that causes liver damage, fibrosis and numerous cell mutations.

Reducing the sickling is also significant because sickled cells are more prone to being damaged when passing through narrow capillaries.

Further, elephants may have a more robust mechanism for killing damaged cells that are at risk for becoming cancerous.

«The cells that are in low nutrient conditions end up being much more viable, likely because they have waited for the damaged DNA to be repaired before starting to divide again,» explains Julia Klermund.

Checkpoints stop cells from dividing; thereby allowing more time for the cell to repair damaged genetic material.

Because it more effectively induces cancer cell apoptosis in p53 - deficient tumors, FL118 is especially effective against late - stage cancers, which usually lose functional p53 and are resistant to DNA - damage drugs.

After tracking the injected cells in the mice for more than 10 days using bioluminescence and fluorodeoxyglucose (FDG)- positron emission tomography (PET) imaging, they found that the injection of the senescent cells into the knee region caused leg pain, impaired mobility and characteristics of osteoarthritis, including damage to surrounding cartilage, X-ray changes, increased pain and impaired function.

When injuries or illness damage specific parts of a body, cell death generates even more of this so - called circulating DNA.

«But this study has shown us that when we run into severe pathological conditions like heart and liver disease it would be more beneficial to inhibit the TRIM21 protein because it is preventing the cell from protecting itself against damage.»

As more saturated fatty acids enter the cell, those islands grow in size, creating increasing inelasticity of the membrane and gradually damaging the entire cell.

A mutation in the virus led to more brain cell damage and much smaller brains (right).

What's more, the repeated light exposure damages cells and their fluorescent labels.