Sentences with phrase «more cell growth»

Those taking the supplement showed substantially more cell growth in the tissue removed than the women who were not taking the soy.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

As a cancer researcher, do you think the mechanisms of tumor growth are somehow changing to come into line with your perceptions, or is it possible that the process of our learning more about DNA mutations and cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going on under our noses?

Evidence of the fact that union differentiates is to be seen all round us — in the bodies of all higher forms of life, in which the cells become almost infinitely complicated according to the variety of tasks they have to perform; in animal associations, where the individual «polymerises» itself, one might say, according to the function it is called upon to fulfil; in human societies, where the growth of specialization becomes ever more intense; and in the field of personal relationships, where friends and lovers can only discover all that is in their minds and hearts by communicating them to one another.

It remains an important nutrient for optimal cell division and growth, making the reasons to take it during pregnancy all the more obvious.

I had my follow - up CT scan about a month ago to check and make sure that I had no more growth and no more active cancer cells.

In the new study, the scientists expressed surprise that the early abnormal growth of brain cells they observed in the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autism.

They're harmless, but do keep an eye on the size and quantity of these spots, since having six or more that are larger than a quarter may be a sign of neurofibromatosis (a genetic disorder that causes abnormal cell growth of the nerve tissue).

Cells have more than one trick up their sleeve for controlling certain genes that regulate fetal growth and development.

These «aggregates» can comprise hundreds of thousands of cells, be up to 2 mm in diameter and be eight times more resistant to chemotherapy drugs — firstly because hypoxic conditions are created inside the aggregates and secondly because these tumour cells reduce growth and are therefore less sensitive.

To get more cells, researchers from Advanced Cell Technology in Worcester, Mass., grew clusters of human embryonic cells in a precise cocktail of growth factors and other cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developmCell Technology in Worcester, Mass., grew clusters of human embryonic cells in a precise cocktail of growth factors and other cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developmcell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific development.

Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2 - DG, according to scientists in Salford, UK.

Higher amounts of insulin are more likely to cause cells to lose their ability to regulate growth, a precursor to cancer.

Lowering levels of AMACR reduces the growth of cancer cells, and these cells revert to more «normal» behaviour.

This maneuver «froze» the cells in a quiescent phase of their division cycle and may have made their chromosomes more susceptible to being reprogrammed to initiate the growth of a new organism after the nuclei were transferred into an egg.

A team at Emory University is embedding electrodes in glass cones filled with nerve - growth factors that encourage brain cells to sprout more dendrites and axons.

Women with the KRAS - variant are also more susceptible to triple - negative breast cancer, tumors whose growth is not fueled by the hormones estrogen and progesterone, or by the presence of a particular genetic mutation known as HER2, which promotes cancer cell growth.

Simultaneously, the research team in CRAG led by Ana Caño Delgado discovered more details on the root growth and its post-damaged cell repair capacity, which have been published in the Journal of Cell Sciecell repair capacity, which have been published in the Journal of Cell ScieCell Science.

That could then lead to even more fueling stations that can accept hydrogen and support the continued growth of the fuel - cell electric vehicle market.»

By comparing proteomic and RNA - sequencing data from people on different exercise programs, the researchers found evidence that exercise encourages the cell to make more RNA copies of genes coding for mitochondrial proteins and proteins responsible for muscle growth.

In the current study, Yu - Shang Lee, PhD, of the Cleveland Clinic, together with Jerry Silver, PhD, of Case Western Reserve Medical School, and others, used a chemical that promotes cell growth along with a scar - busting enzyme to create a more hospitable environment for the nerve graft at the injury site.

A few starter cells scraped off one's arm, a night stewing in growth medium, and voilà: a vehicle for passive aggression more poetic than the world has seen since the days when it was still possible to irritate people to the point that they'd burn you at the stake in front of a crowd.

The outcome was: the more distantly two types of mitochondria within an egg cell were related, the more frequently a growth advantage was noted in favor of one of the two types of mitochondria.

It spurred the fastest growth of fibroblast cells, with 17 per cent more cells formed after six days as in a control culture.

This caused atypical growth of blood - forming stem cells that were more likely to produce the abnormal B cells most common in B - ALL.

A study by Mo's group in a 2011 issue of Experimental Biology and Medicine (236:604 - 613) showed that normal fibroblasts are 10-fold more resistant than murine B16 melanoma cells to geranylgeraniol - mediated growth suppression.

Then came a new step: They carefully extracted the fragile, immature eggs and some surrounding cells from the follicles, and allowed them to further mature on a special membrane in the presence of more growth - supporting proteins.

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find.

The stem cell model says that tumor growth is more hierarchical, mainly driven by a subset of cells that can make new copies of themselves and give rise to the other cell types the tumor contains.

The team is also planning further research to find out more about why pancreatic cancer cells rely on PAK4 and what other proteins and pathways PAK4 is interacting with to drive cell growth and migration.

More importantly, the fibronectin part of the complex is expressed during a cell's transition to cancer and plays a role in cell growth, migration and differentiation.

«We now know much more about metabolic reprogramming of cancerous tissues in human patients, particularly that the activation of pyruvate carboxylase is important to lung cancer cell growth and survival,» said Fan, UK professor of toxicology and faculty member of the Markey Cancer Center and CESB at the University of Kentucky.

«From providing growth factor support and ensuring proper oxygen and nutrient delivery to the brain to trimming of obsolete synapses and recycling waste products, recent findings show that glial cells do much more to ensure brain activity is optimized,» Kozai says.

The team then cultured the cells for several months in a bath of growth - promoting proteins, trying to get the cells to reverse course and become more like stem cells.

Therapies could seek to increase or decrease the amount of HIF to deliver more oxygen to anemic cells or suppress cancerous growth.

In order to identify the cancer stem cells from other cells in the tumor, the research team studied epigenetic mechanisms that distinguish between the least - sorted cells, with endless division properties and a potential to create growth, and the more sorted cells which lack this ability.

An experimental drug that targets abnormally high levels of a protein linked to cancer growth appears to significantly reduce the proliferation of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results of a study led by Johns Hopkins scientists.

owever, unlike modern cells the scientists believe this could only happen if the membrane was «leaky», enabling protons to leave the cell spontaneously so more protons could enter to power growth.

Further investigations could pave the way to a more complete understanding of the genetics and metabolomics of cell growth in yeast and the underlying mechanisms relevant to other settings in which cells face challenging conditions, such as cancer progression and the evolution of drug resistance.

In tests on human breast cancer cells and in special immunodeficient mice with tissue grafts, the scientists found that both agents interfered with genes involved with breast cancer cell growth, resulting in more cancer cells.

Cranberries also contain a number of compounds that benefit human health — including some that have been shown to inhibit the growth of tumor cells — and sequencing work may reveal more about them.

They found that normal cells grow faster when in an organoid with cells expressing RasG12V at low levels, but required more than one mutant cell to kick - start this abnormal growth.

The images show how a growth factor caused cells to change forms and regroup from tight packs of epithelial cells to more mobile, loose arrays of mesenchymal cells — information useful for studying cancer and wound healing.

Jasper says researchers at the Buck are also testing homologues of rapamycin that are more specifically aimed at TOR Complex 1 — a key complex containing TOR that regulates cell growth and metabolism in all complex organisms.

However, the mice treated using both celecoxib and stem cells showed better wound healing and more tissue growth a week later, compared with untreated mice or mice treated using stem cells or celecoxib alone.

So the observed «interactive effect» is nothing more than the standard inhibition of cell growth by radiation.

The Salford team recently showed Vitamin C to be up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2 - DG, but they say that when Vitamin C is combined with an antibiotic, it is up to ten times more effective, making it nearly 100 times more effective than 2 - DG.

Thus, the molecule's observed «effect» on cell growth is nothing more than the well - known cytotoxic effect of alcohol.

In order to learn more about this process, Alexander Skupin and his team treated blood stem cells from mice with growth hormones and then watched closely how these progenitor cells behaved during their differentiation into white or red blood cells.

In particular, consumption of whole plant foods slows digestion and provides higher amounts and a more favourable balance of essential and vital nutrients per unit of energy; resulting in better management of cell growth, maintenance, and mitosis (cell division) as well as regulation of blood glucose and appetite.