Sentences with phrase «more copies of variants»

If changing conditions favor, say, tallness, then tall people will have more offspring, and more copies of variants that code for tallness will circulate in the population.

Not exact matches

The researchers are analyzing more patient samples looking for additional cases of multiple copy number variants to continue their investigation of what may trigger this rare phenomenon.

More than one quarter of children with two copies of a high - risk variant in a specific group of genes develop an early sign of celiac disease called celiac disease autoimmunity (CDA) by age 5.

Subsequent research has established that carrying two copies of the harmful variant increases risk 12 times compared with having two copies of the more common form, APOE3.

For the particular variant of interest, one version, the T allele is more common, and of 196 patients, 135 had two copies of the T allele.

And children with two copies of the R variant will make more alpha - actinin - 3, setting them up for possible achievement in power or endurance sports including football, weight - lifting or sprinting.

In the lifestyle modification group, however, even individuals with two copies of the variant were no more likely to develop type 2 diabetes than participants without the variant, the team reports 20 July in the New England Journal of Medicine.

The researchers found that participants in the control group with two copies of the variant were 80 % more likely to develop the disease than those without the variant.

With its large sample size, this study had the power to find copy number variants with large effects that occur in more than 0.1 percent of schizophrenia cases.

The researchers found that people who have more copies of the gene variants (by inheriting a copy of each advantageous variant from both parents), had the least amount of oxygen in their blood and used it more efficiently than people without either variant, or only one copy from one parent.

The researchers also found that these copy number variants occurred more frequently in genes involved in the function of synapses, the connections between brain cells that transmit chemical messages.

The investigators found that people who carry a single copy of the KL - VS variant of the KLOTHO gene, roughly 20 percent of the population, have more klotho protein in their blood than non-carriers.

Those with one copy of the variant are at more than 30 % greater likelihood of developing BCC than those who do not carry the variant, while those who carry two copies are at more than 50 % greater risk.

«The variant that we discovered is common: Most people have one or two copies of the version of the gene that is linked to accumulating more pathology as you get older,» said lead author Dr. Lori Chibnik of Brigham and Women's Hospital.

Molecular profiling of large tumour numbers has also allowed the annotation of more than 13 million non-coding mutations, 18 029 gene fusions, 187 429 genome rearrangements, 1 271 436 abnormal copy number segments, 9 175 462 abnormal expression variants and 7 879 142 differentially methylated CpG dinucleotides.

Ford C - Max Energi: While the Fusion Energi posted a surprisingly high number of its own, the 988 C - Max Energis sold in June was even more significant... considering the non plug - in variant of the C - Mas only sold 1,952 copies.

Publishing DC's 52 - variant - cover gimmick with Justice League of America # 1 seems to have paid off, as ICv2 estimates Diamond Comic Distributors sold more than 300,000 copies to comics shops last month.

This means that dogs with a single copy (Sn) of the MITF variant will express a limited white spotting pattern, while dogs that have 2 copies (SS) of the variant will exhibit more white with very little color.

«Rather than take these «doubles» and «triples» as evidence of an iconoclastic modernist mindset — like, say, a forerunner of Andy Warhol's proliferating pop culture symbols — it may be more appropriate to locate them in the lineage of Titian or Rembrandt, both of whom made thoughtful copies or variants of the same subject,» says David Anfam.