Sentences with phrase «more duration risk»

If one believes that interest rates will decrease, taking on more duration risk can make sense.

Potenza: As the yield curve flattens, investors get less compensation for moving further out on the curve and taking on more duration risk.

Not exact matches

«It's more market risk than many people might be used to taking, but I don't think it's worse than duration or credit risk currently,» he said.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Indeed, this duration of couchification is the most telling aspect of the study: Those who got up more frequently — presumably, even to stand and fetch the cable remote... or a glass of water in the kitchen, let us hope — were less at risk.

Given that I think curve flattening may continue in 2018 — I am somewhat more comfortable with duration risk than credit risk, at least in the United States.

Collins has adopted a more defensive position in the last 18 months, reducing duration and credit risk by scaling back overweight positions in high - yield and municipal bonds, but he's sticking with allocations to intermediate term funds.

If you are a prodigious saver, are willing to keep your money safe for a set duration of time while earning an interest rate above the current risk free rate 10 Year Treasury, and are concurrently investing in other more aggressive instruments, I recommend diversifying your capital into a 5 - year CD account or longer duration.

Lower duration TIPS funds» headline yield level may be lower, but their portfolio impact may be more beneficial than broad - based TIPS because they require less duration (risk) to earn that yield,» added Mazza.

Yes the Index - linked fund is more susceptible to interest rate risk than the regular bond fund, but not by the nature of it being a linker, it's because the average duration is longer.

The world is VASTLY more leveraged today than it was in the 1980s or even the early 2000s, so any rise in rates (duration) is going to wound risk assets rather quickly.

Municipalities have more risk than U.S. government bonds of similar duration and credit quality.

I think the data has more to say about duration and maturity risk than anything.

This reflects both the increasing risk of long - dated government bonds — as rates drop, duration or rate sensitivity has risen — and the fact that traditional bonds have never been more expensive.

Fidelity ® Short Duration High Income Fund (FSAHX) This fund might be appropriate for investors looking for higher yield who are willing to take on more credit risk while limiting interest rate risk.

If we honest about it for much of 2017 he was Sh ** We need more CM partnership options in a season duration — reliance upon ramsey to have the impact he showed 3 or 4 seasons ago is a risk.

Women who breastfeed are less likely to get breast cancer (and longer duration reduces the risk more), less ovarian cancer and osteoporosis.

A longer duration of breastfeeding — for example more than 12 months (and this can be over several babies) is more protective, even if you are breastfeeding at all and whether you are mixed feeding with some breast milk and some formula, your breast cancer risks are reduced.

However, the organization also called for more research regarding the benefits of 6 vs 4 months of exclusive breastfeeding.25 Thus far, several studies in industrialized countries revealed that a shorter duration of breastfeeding increases the risk of common infectious diseases, such as respiratory and gastrointestinal tract infections.8, 19,24,26, — , 32 However, in these studies, various definitions of the exclusiveness of breastfeeding were used24, 27,28,30 or the combination of duration and exclusiveness of breastfeeding was not taken into account.8, 31

It is important to note that duration of breastfeeding, the longer a mother breastfeeds in her life (one or more babies and the collective number of months), significantly impacts her risk for breast cancer; the protective effect of lactation on breast cancer risk is cumulative.

This analysis including 7 studies20,23,25,37 - 39, 42 showed that any breastfeeding for more than 6 months compared with a shorter duration was associated with a 17 % decreased risk for childhood leukemia (OR, 0.83; 95 % CI, 0.72 - 0.96).

Some of the many benefits a Postpartum Doula provides for you and your baby include: Better infant care skills Positive newborn characteristics Breastfeeding skills improve A healthy set of coping skills and strategies Relief from postpartum depression More restful sleep duration and quality Education and support services for a smooth transition home A more content baby Improved infant growth translates into increased confidence A content baby with an easier temperament Education for you to gain greater self - confidence Referrals to competent, appropriate professionals and support groups when necessary The benefits of skin to skin contact Breastfeeding success Lessen the severity and duration of postpartum depression Improved birth outcomes Decrease risk of abuse Families with disabilities can also benefit greatly by learning special skills specific to their situation Families experiencing loss often find relief through our Doula services Improved bonding between parent and chMore restful sleep duration and quality Education and support services for a smooth transition home A more content baby Improved infant growth translates into increased confidence A content baby with an easier temperament Education for you to gain greater self - confidence Referrals to competent, appropriate professionals and support groups when necessary The benefits of skin to skin contact Breastfeeding success Lessen the severity and duration of postpartum depression Improved birth outcomes Decrease risk of abuse Families with disabilities can also benefit greatly by learning special skills specific to their situation Families experiencing loss often find relief through our Doula services Improved bonding between parent and chmore content baby Improved infant growth translates into increased confidence A content baby with an easier temperament Education for you to gain greater self - confidence Referrals to competent, appropriate professionals and support groups when necessary The benefits of skin to skin contact Breastfeeding success Lessen the severity and duration of postpartum depression Improved birth outcomes Decrease risk of abuse Families with disabilities can also benefit greatly by learning special skills specific to their situation Families experiencing loss often find relief through our Doula services Improved bonding between parent and child.

Additionally, the U.S. Nurses» Health Study found only women with a lifetime duration of breastfeeding of 2 years or more had a significantly lower risk of coronary heart disease than those who never breastfed.

In adjusted analysis a shorter duration of predominant breast feeding (less than two months) was a risk factor for four or more hospital, doctor, or clinic visits because of upper respiratory tract infections (OR 1.43, 95 % 1.02 to 2.01, p = 0.041), as was partial breast feeding for less than six months (OR 1.46, 95 % CI 1.07 to 2.00, p = 0.018).

Short total reproductive duration was associated with an increased risk of heart failure, which was found to be related to an earlier age at menopause and was more pronounced in women who experienced natural, rather than surgical, menopause.

Aspirin use was associated with a 47 % reduced risk of cervical cancer among frequent users — those who used aspirin seven or more times a week, regardless of duration — and 41 % reduced risk among long - term frequent users — those with five or more years of frequent use.

These results remained largely unchanged after further sensitivity analyses, prompting the researchers to suggest that giving moderate to higher opioid doses for shorter durations may be a more effective way to manage pain after surgery, while minimising the risk of misuse and addiction.

However, Abraham's team found that IBD patients diagnosed at an older age (e.g., 45 instead of 35), those with metabolic syndrome risk factors (diabetes, hypertension, obesity, and high cholesterol), and most importantly, those with longer duration of disease regardless of age at diagnosis, are more likely to develop NAFLD.

This risk increased with longer duration of use, especially if taken for 10 or more years.

The current acceptable risk for fatal cancer among astronauts on the space station is no more than a 3 percent probability of death, and the maximum duration of space missions to stay within this limit is about 18 months.

(1) Use of Echinacea was found to decrease the risk of developing the common cold by more than 40 %, and decreased the duration of the cold by 1.4 days.

Carbohydrate intake has been shown to reduce breath - hold durations, due to more rapid CO2 generation (because of a higher RQ) in subjects who had fasted for 18 h, suggesting that that the risk could be reduced by proper carbohydrate intake and that breath - hold diving on an empty stomach may be dangerous.»

New Recommendations from the National Sleep Foundation - The Atlantic January 2015 - Poor Sleep in Adolescence Predicts Future Problems, Study Says - Los Angeles Times January 2015 - How Sleep Keeps You Healthy, Helps You Heal - Discovery News September 2014 - Lack of Sleep Increases Risk of Failure in School Among Teens - Science World Report, from Sleep Medicine August 2014 - Sleep Woes in Old Age May Be Linked to Brain Cell Loss - Health magazine August 2014 — University of Chicago Study: Getting More Sleep Could Cut Junk Food Cravings in Half — CBS News August 2014 — University of Montreal Study Shows Learning Is Best Enhanced During Sleep - Jewish Business News February 2014 - Link Found between Sleep Duration and Depression - Psych Central February 2014 - Less Sleep, More Time Online, Raises Risk for Teen Depression — National Public Radio

Comparable yields and contrasting durations indicate that, while tobacco may be the flavor of the month, the market (and hopefully the end user) associates much more risk with tobacco than with nurses.

This reflects both the increasing risk of long - dated government bonds — as rates drop, duration or rate sensitivity has risen — and the fact that traditional bonds have never been more expensive.

See why duration tells you more about a bond's risk.

These ETFs, now available for the municipal, corporate and high yield sectors, enable more precise control over duration risk than previous fixed income ETF offerings.

@Jerry, I agree that today the main risk in bonds is duration risk (AKA interest - rate risk)-- last weekend's Barron's has an interview with the UBS Wealth Management top managers pointing out this means convincing investors to switch from Treasuries and investment - grade corporates to well - selected junk (HYLD is a jewel there — DO N'T go for index funds in bonds, very differently from ones in stocks they make no sense... where's the sense in wanting to lend more to companies which are more indebted?!

Rising rates could, over time, help restore the attractiveness of lower - risk government and shorter - duration debt — at the expense of more richly valued credit sectors that have benefited from the hunt for yield in recent years.

Compared to the Bloomberg Barclays Aggregate, the Balanced Risk Index aims to diversify the sources of risk and return, which has resulted in a tilt towards generating income and a more defensive (lower) duratRisk Index aims to diversify the sources of risk and return, which has resulted in a tilt towards generating income and a more defensive (lower) duratrisk and return, which has resulted in a tilt towards generating income and a more defensive (lower) duration.

For investors willing to risk a little more duration, illiquidity, credit exposure, or global exposure there are roughly 1500 funds monitored by Trapezoid.

And so this lengthening of maturities and lengthening of duration has caused these indices to be more interest rate sensitive and some cases, more interest rate sensitive than they've historically ever been, and so by being flexible and not using that as the basis for thinking about the risk of one's investments, what you can do is reduce the interest rate sensitivity of your fixed income portfolio.

As we've discussed before, the duration of a bond fund is an important indicator of its risk level because the longer the duration, the more the fund's price will fluctuate as a result of changes in market interest rates.

Considering these dynamics, we find duration (a measure of interest - rate risk) to be somewhat more concerning today than in recent memory and the prospects for risky assets will vary depending on how future duration moves are divided between breakevens and real rates.

The higher the duration, the more the bond's price will change when interest rates move, therefore the higher the interest rate risk.

Bond prices are impacted by interest rate changes — bonds with higher durations carry more risk above and have higher price volatility than bonds with lower durations

The more curved the relationship between price and interest rate changes, the more inaccurate duration becomes as a risk measure.

This extends its duration, given it pushes more of the cash flow to be paid out at a later date, and increases its interest rate risk.

High durations and higher credit risk will be associated with higher volatility more generally.

As mentioned, if a higher yield to maturity is due to higher duration risk, then this bond will be more subject to interest rate risk.