Sentences with phrase «more effective cancer therapy»
The scientific goal of the Developmental Cancer Therapeutics Program is to discover and characterize unique agents and pathways that will impact the development of more effective cancer therapies and to translate these discoveries into clinical applications by using proof - of - principle, early phase clinical and correlative science studies.
http://www.hollingscancercenter.org/ Not exact matches
One setback for these therapies which use the body's immune system to fight cancers is that they are, at times, more effective in certain patient pools than others.
RADIATION therapy to treat cancer is more effective in some people than others.
The research suggests that immune therapy for cancer might be more effective if combined with drugs that inhibit NF - kB.
«We propose that highly specific ME3 inhibitors could provide an effective therapy for many cancer patients, but more research must be done.»
Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction of tumor - initiating cells,» which will be published online November 23 in The Journal of Experimental Medicine.
They have had several successes in identifying pro-metastasis microRNAs skin cancers and anti-metastatic microRNAs in breast cancer, discoveries that could in the future lead to new, more effective therapies.
«RYBP would make cancer cells more sensitive to DNA damage, which would make chemo or radiation therapy more effective,» said Mohammad Ali, a postdoctoral fellow and the lead author of the study.
Therefore, safer therapeutic therapies that are more effective are being sought for this deadly type of cancer in women.»
«By helping us understand that lower levels of RNF125 confer resistance to BRAF inhibitors, we have a new strategy to stratify patients for currently approved therapy versus participation for human clinical trials to investigate whether targeting JAK1 will be more effective in patients whose tumors exhibit reduced RNF125,» said Keith T. Flaherty, M.D., associate professor, Harvard Medical School, and director of Developmental Therapeutics, Cancer Center, Massachusetts General Hospital, and co-author of the study.
Hematopoietic stem cell transplantation (HSCT), once considered an effective yet risky alternative to drug therapy for blood cancer, has become more accessible and successful in a wide range of patients as a result of major advances in transplant strategies and technologies.
«If immune cell therapies for cancer or autoimmune diseases (like rheumatoid arthritis, for example) are going to be safe and effective alternatives to more traditional medications, we must gain control over the activity of the cells to reduce risks of toxicity to the patient,» said Roybal.
The researchers are now looking at how ICOS signals can be altered to diminish autoimmune disorders and augmented for more effective vaccine development, and are beginning research on how ICOS signaling may benefit Chimeric Antigen Receptor - T cell (CAR - T) therapies, which involves engineering of patient's own immune cells to recognize and attack their cancers.
«Combination therapy may be more effective against the most common ovarian cancer.»
In the Cancer Cell article, the researchers describe how various anticancer drugs, including cisplatin and the targeted therapy vemurafenib, which targets melanomas with the BRAF mutation, become more effective when co-delivered with phenformin.
«This breakthrough could lead to more effective therapies for women with this very common subtype of breast cancer and be the therapeutic target that the drug companies have been waiting for.»
«Understanding how cancers suppress the immune system is the key to identifying more effective immuno - therapies,» said Brent Hanks, M.D., Ph.D., at Duke and senior author of the study.
When the researchers removed FAK from blood vessels that grew in melanoma or lung cancer models, both chemotherapy and radiation therapies were far more effective in killing the tumors.
A new study published in the International Journal of Molecular Sciences, describes a new concept of how these two cancers may evolve in a similar way and may eventually lead to more effective therapies for both.
The successful combination of these two therapies results in the growth of specialized vessels that deliver cancer - fighting immune cells to the tumor, potentially leading to more effective treatments and longer survival periods.
Researchers have now found a way to map those alternate routes by studying individual cancer cells, suggesting approaches for developing more effective combination therapies.
«Knowing more about why cancer rates differ between males and females will help us understand basic mechanisms in cancer, seek more effective therapies and perform more informative clinical trials.»
«If you were to compromise the altered physiology of tumors with something like RHT, the cancer cells are going to be less able to tolerate other therapeutic insults, and that probably would give you more effective therapies.
Penn Medicine's Hematologic Malignancies Translational Center of Excellence seeks to redefine the diagnostic and therapeutic approach to blood cancers in order to provide more effective targeted therapies.
Martin Carroll, MD and Edward Stadtmauer, MD are leading efforts at this TCE to redefine the diagnostic and therapeutic approaches to blood cancers — including leukemia, lymphoma and myeloma — and provide more effective targeted therapies.
The Hematologic Malignancies Translational Center of Excellence (TCE) is a multidisciplinary center that seeks to redefine the diagnostic and therapeutic approaches to blood cancers, including leukemia, lymphoma and myeloma, and provide more effective targeted therapies.
Dual HER2 blockade with lapatinib and trastuzumab plus AI therapy was more effective than trastuzumab plus AI alone in HER2 +, HR + metastatic breast cancer.
He continues to investigate and optimize CAR T cell therapy, to make it more effective not only for blood cancers, but also to help patients with other types of cancer.
Our surgical oncologists provide the highest - quality cancer care to diagnose and remove tumors, debulk tumors to help make chemotherapy or radiation therapy more effective, and relieve symptoms or side effects of therapies.
The tests are based on research conducted by Columbia University Irving Medical Center (CUIMC) investigators — and could pave the way for a more precise approach to cancer therapy and help find effective drugs when conventional approaches to precision medicine have failed.
The goal is to use these tools to gain a deeper understanding of the disease processes in cancer, diabetes, heart disease and mental health, and ultimately to try and find safer and more effective ways of using stem cells in medical research and therapy.
An unusual observation by Hopkins scientists about how testosterone affects prostate cancer cells may lead to more effective radiation therapy in men with high - risk disease.
This will create strong synergy for a unified, multidimensional project aimed at generating more effective CAR T cells therapy for pancreatic cancer patients, with potential broad implications for immunotherapy directed toward other cancers.
The co-delivery of small molecular drugs with nucleic acids can improve gene transfection efficiency, reduce side - effects of these drugs, and achieve the synergistic effect of drug and gene therapy for the more effective treatment of cancer.
Although recently approved therapies can increase progression - free survival by a few months, «we think this novel screening system has the potential to uncover new, more effective medications that could be targeted more specifically at a patient's cancer,» Lengyel said.
We need to accelerate the pace at which we develop an early detection blood test for pancreatic cancer and more effective therapies.
Located within the New York State Center of Excellence in Bioinformatics and Life Sciences, immediately adjacent to Roswell Park laboratories and research support facilities, the company will create employment opportunities within the life sciences and develop new therapies designed to give cancer patients better, more effective treatment options.
I was told that he had developed a non-toxic therapy that was more effective than chemo or radiation on even the most aggressive cancers.
I find this line of research quite exciting as it suggests less toxic, yet more effective future cancer therapies.
Iodine has been shown to be an effective therapy for such conditions as breast and uterine fibroids, breast cancer, and more.
We need not necessarily have to go into nutritional ketosis, although some people are healthier doing so, and as an effective cancer therapy it is becoming more popular.
Studies show fish oil can make conventional cancer drugs more effective and provides an effective therapy on its own.
Serving 2,000 patients a day, the JCCC is a major source of discovery of the nature of cancer and of the development of more effective approaches to cancer prevention, diagnosis, and therapy.
The advantages for a dog participating in a clinical trial are that the dog is receiving treatment that is expected to be as effective or more effective than standard therapies, the dog is helping veterinarians learn important information that is expected to help other dogs and even humans with bladder cancer, and the dog is receiving some «hope» if standard therapy has failed.
The goal of a surgical intervention in cancer treatment is to remove or reduce the primary cancerous tumor and allow either chemotherapy or radiation therapy to be more effective.