«If we could turn back the clock and peer inside this cell, would its cellular organization have been like that of an archaeal cell or
more eukaryote - like?»
Not exact matches
Despite that archaeal cells were simple and small like bacteria, researchers found that Archaea were
more closely related to organisms with complex cell types, a group collectively known as «
eukaryotes».
In the domain system,
eukaryotes have
more in common with archaean prokaryotes than bacterial prokaryotes.
Even
more notable, Loki has genes that code for proteins involved in phagocytosis, the process by which one cell can swallow another — and widely believed to be the way
eukaryotes acquired mitochondria, a cell's power source.
Cells from animals, plants and fungi, which make up the
eukaryotes, are much
more sophisticated.
The researchers predict that, when Loki is finally isolated or cultured, «it will look
more like an archaeon than a proto -
eukaryote and will not have internal compartments or a vesicle - trafficking network.»
That's true of nearly all
eukaryotes, and the
more complicated the organisms, the
more of those sequences you have.
Mitochondrial merger
Eukaryotes have a number of innovations compared to their
more primitive archaeon ancestors.
But its morphology and / or cell cycle might have complexities
more often associated with
eukaryotes.
«Bacteria are
more similar to
eukaryotes than we thought.»
«There was
more push back than I expected about how easy it is to work in
eukaryotes,» he said, noting that one judge pointed out that there's a difference between expectation and hope.
Although the majority of genes related to energy production, cell division, and metabolism in M. jannaschii are most similar to those found in Bacteria, most of the genes involved in transcription, translation, and replication in M. jannaschii are
more similar to those found in
Eukaryotes.
Their emergence
more than one billion years ago was a foundational event in the development of
eukaryotes, which include plants, animals, protists and fungi.
He notes that this adds to a long line of studies showing that bacteria are
more and
more similar to
eukaryotes and are not just «bags of enzymes.»
The reason for the disparity may be that the standard computer annotation method was largely developed for the genomes of simple (prokaryotic) organisms, not for the
more complex sequences found in the genomes of humans and other
eukaryotes.
Lane believes the crucial step in the evolution of the
eukaryotes was acquiring mitochondria, which would have provided the energy to develop
more complicated cellular processes and acquire a larger genome.
Eric Wynter describes the internalisation of bacteria into proto -
eukaryotes to become mitochondria as being «
more unlikely, perhaps, than the appearance...
But intriguingly, the Lokiarchaea appear to have
more than 100 genes coding for sophisticated cellular functions such as deforming cell membranes and forming and transporting bubble - like vesicles around the cell — functions that are usually only seen in
eukaryotes like us.
After comparing the sequence to those of a variety of other organisms, the researchers concluded that the Mimivirus lineage dates back some 3.3 billion years to the separation of early life into three major divisions: archaea, bacteria, and the
more complex
eukaryotes.
Informed by
more than 1,000 newly sequenced types of microbe, Banfield's new tree reveals the diversity and long lineage of bacteria, which, along with
eukaryotes and archaea, represent the three main domains of life.
Eukaryotes include plants and animals and have
more complex cells with a nucleus and other organelles enclosed in a membrane.
Some microbes merged with hydrogen - producing microbes (probably multi-functional ancestral mitochondria) to become
eukaryotes that later developed into multi-cellular «animals» that survive and breed in anoxic conditions, without oxygen (phylum Loricifera, which includes Spinoloricus at left —
more).
Unlike the prokaryotic bacteria (and archaea), the
more complex
eukaryotes have a nucleus and other organelles within the cell and so are also bigger.
CaaX processing is a posttranslational modification of the carboxyl - terminus of
more than one hundred proteins in
eukaryotes that are essential for growth, development and survival.
Other theories hold that the prokaryotes that gave rise to early
eukaryotes were probably from the Domain Archaea, both because of several key characteristics and because DNA sequence comparison suggest that archaeans are
more closely related to the
eukaryotes than are eubacteria.
Despite that archaeal cells were simple and small like bacteria, Woese found that Archaea were
more closely related to organisms with complex cell types, a group collectively known as «
eukaryotes».
This pathway is slow - acting,
more ancient than transmembrane receptors, and is highly conserved across
eukaryotes.
However, sexual reproduction in higher
eukaryotes is
more complex than meiosis alone, and has evolved independently in plants and animals.
«This is the key to how
eukaryotes can evolve
more quickly than prokaryotes,» he says.
With the sequencing and annotation of genomes and transcriptomes of several
eukaryotes, the importance of noncoding RNA (ncRNA)- RNA molecules that are not translated to protein products - has become
more evident.
Eukaryotes are far
more complex than prokaryotes and thus far
more difficult to genetically engineer.