But cardiomyocytes that had been mixed with high levels of glucose matured late or failed to mature altogether, and instead generated
more immature cells.
Not exact matches
A newborn has
more red blood
cells than his body needs, and often, when a baby's
immature liver can't process them quickly enough, a yellow pigment called bilirubin (a by - product of the red blood
cells) builds up in the blood.
What's
more, the live
cells in breast milk that protect babies from infection can be even
more important for premature babies: Preemies face a higher risk of infection because their immune systems are particularly
immature.
Then came a new step: They carefully extracted the fragile,
immature eggs and some surrounding
cells from the follicles, and allowed them to further mature on a special membrane in the presence of
more growth - supporting proteins.
If a woman has an abortion, she's left with a large number of these
immature cells lining her breast ducts, and she is therefore
more vulnerable to cancer down the road — 30 percent
more vulnerable, Brind says, than a woman who has never had an abortion.
A new type of pluripotent
cell that genuinely corresponds to the
more immature, pre-implantation stage has been identified and can now be cultivated in the laboratory.
Mature embryonic stem
cells cultivated in the laboratory can, under the right conditions, be backed up in their development to the
more immature stem
cell type.
When Sukumar and the others depleted the HOXA5 protein in other breast
cell lines in the lab, the
cells became
more immature, or «stem like,» as well as
more mobile.
Glioblastoma
cells from patients that could be linked by the gene signature analysis with an
immature origin generally showed a higher sensitivity to cancer drugs than glioblastoma
cells that were associated with a
more differentiated
cell of origin.
«These
immature myeloid
cells appear as a main source of circulating suPAR,» says Jochen Reiser, MD, PhD, principal investigator and senior author of the study presented in Nature Medicine, who has been working on solving the mysteries of suPAR for
more than a decade.
Now, researchers at The Wistar Institute have discovered how STAT3 behaves in
immature myeloid
cells known as myeloid - derived suppressor
cells (MDSCs), and they believe they have found the basis for a much
more effective method of using STAT3 inhibitors to stop cancer progression in its tracks.
A major scientific puzzle, said Singh, has been how and why
immature hematopoietic stem
cells initially express genes that are characteristic of
more than one
cell lineage.
Specifically, we're focused on stem
cell maturation — taking a
cell from an
immature to a
more mature state so that it acts as a better substrate for adult tissue functions.
The intestinal lining of people with Crohn's disease and IBS (irritable bowel syndrome) appear to be
more sensitive to the effects of food lectins because the lining is constantly being replaced by new tissue that is made up of
immature cells that are
more glycosylated and thus
more susceptible to lectin attachment.
The bone marrow should respond to anemia by producing
more red blood
cells; therefore, an increase in the number of
immature cells called reticulocytes should be seen on lab results.