Sentences with phrase «more inflammation with»

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These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Reportedly, the results of the study exceeded even the most optimistic expectations, with the mice gaining more energy, less inflammation and increased muscle tone.

It aids in digestion, relieves inflammation, and provides you with your entire daily needs worth for Vitamin C per cup.Pineapple is also rich in nutrients that heal the gut lining, boost mood, improve immunity, relieve indigestion and heartburn, it helps digest protein more efficiently, is great for the kidneys and regularity, and it even contains special antioxidants that promote healthy nails, hair, and skin.

Such as it is gluten free, low glycemic, has minimal impact on blood sugar, higher in fiber, healthier baking option for people with inflammation diseases such as diabetes (I am type 1), it is not processed and natural... and SOO many more!

Consuming fermented foods can cause more inflammation and further Candida progression for many individuals struggling with Candida.

One more pro: curry, with its bitter and drying spices, helps to clear mucus and reduce inflammation as well.

Less inflammation, more energy, and ultimately, more satisfaction with every single bite.

They found that the unique coconut oil antioxidants reduced inflammation associated with arthritis more effectively than current pharmaceutical drugs.

Eating Clean starts with Amie's story, but quickly moves into her 21 - day plan for fighting inflammation; priceless tips for cleaning up your fridge, pantry and diet (and more); tips on eating out; a 2 - week meal plan; and countless recipes using fresh, wholesome ingredients.

It's not to be confused with the more common tendonitis, which involves inflammation of the tendon itself.

Booby Tubes are flax filled cotton cloth tubes that can be heated in the microwave and wrapped comfortably around the breasts to bring blood to the breast tissue - helping with inflammation and allowing the milk to flow more freely.

It is normal that the fingers and fists are brought to the mouth very often and with an unstoppable desire to bite to press the gums, that his drooling is more abundant than usual, produced by the stimulation of saliva produced by the dentition, which present an unusual irritability due to pain in the gums, cry more than necessary, have problems to sleep, refuse food due to increased pain caused by suction, diarrhea due to excess swallowed saliva and low fever cause of inflammation.

Moms and babies who also inflammation such as a food intolerance which limits the absorption of important nutrients or just temporarily dealing with the compromised immune system are also more susceptible to Fresh.

Social behavior influences the immune system — Social isolation leads to inflammation (with some groups 2.5 times more likely to have elevated CRP levels!)

In a study of more than 5,000 people, investigators from Brigham and Women's Hospital have found that greater intake of nuts was associated with lower levels of biomarkers of inflammation, a finding that may help explain the health benefits of nuts.

The arthritis is accompanied or preceded by fever for at least two - weeks that is daily («quotidian») for at least 3 of those days, with one or more of the following symptoms: red rash (evanescent erythematous rash), enlarged liver, spleen or lymph nodes, and inflammation of the tissue lining (serositis) of the lungs, heart, or stomach.

The researchers measured the levels of the proteins in the tissues and fluid of joints from patients with rheumatoid arthritis and with osteoarthritis, the more common joint inflammation caused by physical wear and tear.

When the researchers examined mice with disrupted IL - 27 function, they found that they were more likely than normal mice likely to die when infected with the virus, and that they died as a consequence of rampant lung inflammation.

Ridker and Libby speculated that for an anti-inflammatory to work, it needed to be much more specific; NSAIDs and steroids have broad effects all over the body, and NSAIDs can spur inflammation along with blunting it.

A clinical trial of more than 10,000 heart attack patients reported today supports a novel way to protect them from a stroke or a second attack: with drugs that stop inflammation.

The scientists transferred the twins» gut bacteria to mice predisposed to develop a disease that mimics MS. Twelve weeks after the transplant, about 40 percent more mice with gut microbes from a twin with MS developed brain inflammation compared with mice that got gut microbes from a twin without disease.

Along with learning more about how taste buds are damaged by inflammation, Dando is interested in working toward new treatments for obesity, perhaps by countering the dulled sense of taste.

But in the study group overall, more - inflammatory diets were not linked to fracture and — in fact — the researchers found a modestly lower risk of lower - arm and total fracture in women with the highest dietary inflammation scores.

Their brains also expressed more genes associated with inflammation, compared to the mice fed the low - glycemic index diet.

One possible explanation included in the study: The women with lower inflammation scores were more physically active as a group and therefore were at a slightly greater risk of falls.

Here we show that not only are those more diverse communities associated with higher levels of genital inflammation but also with significantly increased HIV acquisition.»

However, the work does identify a new mechanism to potentially reduce vaginal inflammation and thus HIV risk by helping women with diverse bacterial communities in their genital tract become more Lactobacillus dominant.

Young adults who were breastfed for three months or more as babies have a significantly lower risk of chronic inflammation associated with cardiovascular and metabolic diseases.

The researchers found severed axons in regions with inflammation characteristic of the disease — in several cases, more than 10,000 times as many cut axons as in brain tissue from non-MS corpses.

«The last thing we need from a vaccine is more inflammatory damage,» says Shah, who has been working with Swedish cell biologist Jan Nilsson on a vaccine that boosts the antibodies responsible for gentle plaque removal while damping vessel - damaging inflammation.

In addition, people with more body fat may have higher blood levels of substances that cause inflammation in the joints, raising the risk for osteoarthritis.

People infected with viruses with high replicative capacity had more signs of acute inflammation in the first few months of infection.

«Alcoholic liver disease is a spectrum of conditions that range from hepatic steatosis, which is fat deposition in the liver and it is reversible with sobriety, to alcoholic hepatitis which is a more severe condition characterized by extensive and severe inflammation in the liver and often requires hospitalization,» explained Valentina Medici, associate professor of internal medicine at UC Davis Health System as well as corresponding author for the study.

First, immune - activated mice spent more time in slow - wave sleep, a sleep phase often associated with systemic inflammation.

An emerging controller of the cholinergic effect of inflammation is micro-RNA-132 (5), whose involvement with post-stroke recovery awaits further studies and might open new venues for more rigorous assessment of the post-stroke risk of survival and systematic infection and the identification of conceptually novel targets for therapeutic interference.

«Children with behavioral problems more at risk of inflammation, health problems later in life.»

More severe long - term symptoms include severe headaches, heart palpitations or an irregular heartbeat, nerve pain, problems with short - term memory and inflammation of the brain and spinal cord.

First, white blood cells with a leukemia - promoting gene mutation become more sensitive to signs of inflammation.

The mice that lost bone density in her experiment had started with more bacteria associated with inflammation, a clue she's following up.

S. aureus strains from those children with more severe eczema caused substantial inflammation, whereas other S. aureus strains provoked smaller reactions (Science Translational Medicine, DOI: 10.1126 / scitranslmed.aal4651).

Low - grade inflammation, a condition more prevalent than IBD, was shown to be associated with altered gut microbiota composition and metabolic disease and is observed in many cases of colorectal cancer.

Some alleles corresponded to higher levels of IL - 1ß, and people with these versions of the genes were five times more likely to suffer from stomach cancer — perhaps because a surplus of IL - 1ß, by shutting down acid production and sustaining an inflammation of the infected areas, allows H. pylori to spread further within the stomach, the authors speculate.

Exercise - induced improvements in glycemic control are dependent on the pre-training glycemic level, and although moderate - intensity aerobic exercise can improve glycemic control, individuals with ambient hyperglycemia (high blood glucose) are more likely to be nonresponders, according to a research letter by Thomas P. J. Solomon, Ph.D. of the Centre of Inflammation and Metabolism, Copenhagen, Denmark, and colleagues.

Monkeys shifted to the bottom rungs of the social order were more likely to express high levels of genes associated with inflammation.

Additional evidence supporting the tumor - promoting role of inflammation is the observation that individuals with chronic inflammation are more susceptible to cancers at the site of that inflammation — e.g. patients with Crohn's disease show increased incidence of colorectal cancer.

Without this specific region in Foxp3, Treg cells are much more likely to lose their identity and defect into killer T cells when faced with inflammation and infection, says Zheng.

The existence of the vegetarian allele implies that, for people with this variation, straying from that diet — by eating a lot of red meat, for example — may make them more susceptible to inflammation, because their bodies were optimized for a different mix of inputs.

O'Shea says this may explain why people with conditions resulting in high levels of cellular DNA damage (e.g., cancer, chemotherapy, inflammation and aging) are more susceptible to viral infections.

Nearly half of those with primarily European Caucasian ancestry carry a particular mutation in the toll - like receptor - 1 (TLR - 1) gene that can cause excessive inflammation in joints and more frequent antibiotic - refractory arthritis.

Diabetes appears to diminish the in general more favorable cluster of risk factors of females compared with males, leading to greater differences in central adiposity and risk factors related to coagulation and inflammation between diabetes and nondiabetes in women rather than in men (33).