Sentences with phrase «more lead compounds»

Robotics, genomics, high - throughput screening, combinatorial chemistry, and informatics tools have given companies far more lead compounds to sift through than they had in the past.

Not exact matches

This led to the formation of «mission compounds» and social ghettos where Christians could take their place as one more subcaste or subsect among the thousands of such subcastes and subsects in India.»

Compounding his effect in the engine room is the fact that after scoring yet another fabulous goal at the Liberty Stadium, Ramsey is now sharing the league lead with four goals to go with four more he's added in the Champions League.

Granting this wide - ranging request would further compound confusion in the marketplace and lead to more misleadingly labeled dairy products.

«This was compounded by the fact the government cut back sharply on face - to - face interviews before release, leading to many more mistakes being made, many more criminals being recalled and many more dangerous prisoners putting the public at risk,» Mr Davis argued.

To try to develop a more sensitive probe for isolating individual peptides — short strands of amino acids — from a pool of similar molecules, a team led by chemist Clark Still of Columbia University 4 years ago synthesized small organic compounds that selectively fish out peptides dissolved in chloroform.

A team led by Stuart Licht at the Technion - Israel Institute of Technology in Haifa has come up with a new cathode made from unusual iron - based molecules — iron (VI), or «super-iron,» compounds — that absorb more electrons than manganese dioxide.

And in one of the feature's more exotic essays, we'll profile a Brazilian program that derives its lead compounds from tropical snake venom.

Cyanide compounds are very reactive, so reactions on early Earth could have led to the more complex organic molecules that life needed (Geophysical Research Letters, DOI: 10.1029 / 2009gl040252).

Based on the structural features of those leads, they tweaked the compounds to create scores that were more heavily biased.

The discovery of more than 100 cannabis compounds called cannabinoids over the past several years — along with the identification of an innate cannabinoid system in the human brain and the generation of many synthetic cannabinoids in the laboratory — has led to unprecedented insights, they said.

«The evidence from observation indicates that complex organic chemistry is much more universal than previously thought,» says Fred Goesmann from the Max Planck Institute for Solar System Research, who led the analysis of organic compounds on the Rosetta mission.

A team of researchers led by biophysicists at the University of Washington have come one step closer to designing tailor - made drug molecules that are more precise and carry fewer side effects than most existing therapeutic compounds.

Best of all, the derivatives were even more effective than the original compound, without leading to that worrisome estrogenic metabolite or showing much affinity themselves for estrogen receptors.

MacCoss and Baillie (p. 1810) outline how the synthesis of more effective analogs of lead compounds now takes many cues from the more readily obtained data on bioavailability and toxicity.

«We view arecoline as a lead to other compounds that could be more potent and selective.»

A leading researcher's review of more than a hundred studies of resveratrol, the red - wine compound that has spurred millions of dollars of investment by pharmaceutical and nutritional companies, raises more questions than it answers.

From the test results of each chemical iteration of the lead compound, they were able to alter their chemical structures to make them much more potent.

«Unfortunately, this compound was rather toxic, which led me to think more about the safety of molecules.

The new material, made of a compound called barium stannate, could lead to the creation of smaller, faster, and more powerful electronics, and more efficient solar cells.

In ensuing experiments, Dr. Ding hopes to rely only on microRNAs and pharmaceutical compounds to convert skin cells to brain cells, which should lead to more efficient generation of cells for testing and regenerative purposes.

Too much estrogen results in a compounding problem — increased fat tissue acts as an estrogen - producing organ, which means even more estrogen is released into a man's system, leading to even greater fat production, and so on in a worsening pattern.

Some hidden ingredients may include preservatives, maltodextrin (a cheap filler), chemical compounds like sucralose, sugars, artificial sweeteners, and more that might lead to weight gain and other issues.

«Compound movements access multiple joints and muscle groups, thereby offering a more complete workout in less time,» says Dara Theodore, one of the three lead trainers for Daily Burn's Power Cardio program.

It remains to be seen to what extent these compounds influence inflammation in people and what dosage is optimal, but these results could lead to more streamlined treatment of chronic inflammation.

Further compounding the issue, fat tissue itself produces more estrogen, which leads to a cycle of weight gain that is difficult to escape.

The health crisis, which has led to more than 200 infections, could lead to shift from state to federal oversight of compounding pharmacies.

Only about 46 percent of children aged three through six in families below the federal poverty line are enrolled in center - based early childhood programming, compared to 72 percent of children in families above the federal poverty line.1 Poor children are about 25 percent less likely to be ready for school at age five than children who are not poor.2 Once in school, these children lag behind their better - off peers in reading and math, are less likely to be enrolled in college preparatory coursework, less likely to graduate, and over 10 percent more likely to require remediation if they attend a four - year post-secondary institution.3 All of these issues compound one another to create a cycle of low opportunity: children in poverty are less likely to achieve high educational attainment, and low educational attainment leads to lower median weekly earnings and higher rates of unemployment.

In tandem with twenty - inch Dunlop SP Sport Maxx tires with stiffer sidewalls and a new compound, the added compliance translates into more grip and confidence by better pinning the tires to undulating pavement — as experienced on the «Ring, one reason that it's the world's leading gauntlet for handling development.

Due to the compounding nature of capital appreciation, this type of growth will lead to more tax savings than if you were to take out dividends every year.

Soon, the skin becomes the victim of a secondary bacterial or fungal infection, which triggers more scratching and chewing leading to a vicious cycle that can compound the allergic reaction.

«Rains have become more intense and fall in a shorter period,» and warmer temperatures are leading to faster melting of the Himalayan glaciers, compounding the risks of flooding.

That rebuttal nicely sums up a lot of the accepted facts of unwavering peakoilers, e.g. that it's been conclusively shown that oil price hikes are linked to recession (not really; e.g. wrong macro policy responses to oil - led inflation often tried to tackle it by raising interest rates, which just compounded the problem and possibly triggered recession by itself; uncertainty in price is often more important to investment decisions that which direction it's going in, given that fuel costs are actually not a large % of overall costs.)

Indeed, Canada already is a leading producer of field - grown hemp seed, which is nothing more than a strain of cannabis with the psychoactive compounds bred out.

* Licensed lead Phase I compound for more than $ 240 million in upfront and milestone payments plus clinical reimbursement and high double digit royalties.

Parents frequently assume these symptoms will resolve with time, but often, problems compound or escalate, leading to more maladaptive behaviors.