Sentences with phrase «more potential therapies»
AAF investigators brought six new drugs to clinical trials and many more potential therapies are in the pipeline.
http://www.americanasthmafoundation.org/ Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
MMRF and Memorial Sloan Kettering to launch a new clinical trial to identify potential genomic markers linked to achieving and maintaining deep response to therapy Read More
The finding offers potential for developing both gene therapy and more effective protein replacement treatments for hemophilia A, the most common form of hemophilia.
The current study was designed to clarify the cellular hierarchy underlying glioblastoma, to identify epigenetic factors that distinguish glioblastoma stem cells from more differentiated tumor cells and to suggest potential therapies targeting those factors.
«Unsuspected characteristics of new cystic fibrosis drugs found, offering potential paths to more effective therapies.»
The study paves the way for CRISPR - Cas9 as a powerful gene editing tool with potential therapeutic applications for inherited diseases — leading to more widely available gene therapy techniques.
The same process has been studied as a potential genetic therapy for more than a decade, because you can target any disease gene with matching dsRNA.
Hooker and Van de Bittner note, however, that the tool also has tremendous potential for research applications, particularly for drug discovery in smell - loss therapy and in understanding the relationships between olfactory neuron health and brain health more generally.
In contrast, applied research needs to contribute to a product or therapy, which means that research projects which don't show potential will be dropped to give attention to more promising ones.
However, another way of getting at a similar end - and one with more potential as a therapy - is to find out what the plasticity brake is acting on, and try to artificially boost the process being suppressed.
By tracking and understanding which host cell pathways are manipulated by these T. gondii proteins, scientists can identify potential new targets to develop more effective therapies against highly aggressive solid tumors.
Analyzing more than 120 million patient records and identifying trends of co-occurrence among hundreds of diseases, they created a unique genetic map that has the potential to guide researchers and clinicians in diagnosing, identifying risk factors for and someday developing therapies against complex diseases.
The findings, described in his prize - winning essay,» Refining cell therapy,» could eventually help overcome the major hurdles that currently hinder T cell immunotherapies from reaching their full potential, and offer patients more favorable treatment outcomes.
The more we know about the steps that occur in disease progression, the more opportunities we have to intervene with potential therapies.»
Saez and his colleagues will next focus on using the new screening strategy to uncover more biological pathways that could yield new mechanisms to develop potential therapies.
More niche therapies are in development, which means the potential pool of study participants is diminishing.
Although there remains no cure for Alzheimer's, researchers hope that testing potential drugs or therapies prior to mental decline will prove to be more successful than previous attempts at finding the most effective treatment in the battle against the debilitating disease.
Professor Winder's approach could complement potential therapies currently advancing through clinical trials, making them more effective.
DMAbs, which are produced in the body, have the potential to overcome many of these limitations, reducing cost barriers that would allow such technologically advanced therapies to reach more populations around the globe.
«More research is being conducted with VNA gene therapy and it's hard to deny the potential of this rapid - acting and long - lasting therapy in treating these and several other important illnesses.»
WGS currently requires significantly more manual analysis, so combining this method with artificial intelligence could help doctors identify potential therapies from WGS for more patients in less time.
«It suggests to us that targeting the pathways used in regulating cell fate decisions — how stem cells choose between cell proliferation and differentiation — could be a more effective way of halting tumours in their tracks and lead to potential new therapies.»
After hearing a brief explanation that laid out the different sources of stem cells (but left undiscussed their current uses or future potential for therapy), the respondents offered a slightly more nuanced set of views, and only a slight majority (52 %) supported embryonic stem cell research.
With cellular therapy holding enormous promise for future cures and treatments, Black Beret Life Sciences is committed to doing what it can to help the field reach its full medical potential by creating a more efficient regulatory framework in the U.S.
Yamanaka said, «We hope that further trials of iPSC - based therapies, accompanied by basic research focused on gaining more detailed, molecular insights into the process of cellular reprogramming itself, will result in unveiling the full potential of iPSCs in the next decade.
University of California San Francisco researchers may have discovered why the experimental anti-cancer drug Onyx - 015 works more broadly than had been expected, a finding that could solidify and expand use of the drug and which reveals a potential new target for therapy that could prompt the development of other cancer drugs.
By considering patient experiences and feedback, researchers and advocates alike can learn more about the safety and efficacy of potential stem cell therapies.
«Our findings of this potential biomarker are exciting — it means we are closer to being able to select therapies more specifically for a patient with colon cancer.
Although researchers are excited about the potential to use CRISPR to create therapies from people's own blood, immune, and stem cells, thousands more genetic conditions affect everything else.
4/7/2008 From Bench to Bedside in One Year: Stem Cell Research Leads to Potential New Therapy for Rare Blood Disorder A unique partnership between industry and academia has led to human clinical trials of a new drug for a rare class of blood diseases called myeloproliferative disorders (MPD), which are all driven by the same genetic mutation and can evolve into leuk... More...
They provide a new target for potential therapies, and they furnish a model system for more rapid and less expensive study of prion diseases and potential treatments.
Once the future stem cell therapist does the therapy, stem cells have the innate potential to produce more cells.»
This will create strong synergy for a unified, multidimensional project aimed at generating more effective CAR T cells therapy for pancreatic cancer patients, with potential broad implications for immunotherapy directed toward other cancers.
Thanks to all of this, today there is more talk about how one goes from basic science observations to potential therapies.
Learn more about the potential benefits of cell therapy for chronic conditions here.
Although recently approved therapies can increase progression - free survival by a few months, «we think this novel screening system has the potential to uncover new, more effective medications that could be targeted more specifically at a patient's cancer,» Lengyel said.
Methotrexate and cyclosporine clear psoriasis more quickly than Soriatane, for instance, but are less appropriate for long - term «maintenance» therapy due to the potential for liver and kidney damage.
Given the high risk of side effects from antidepressants, one may only hope that more doctors and health professionals will begin to look into the potential of using yoga as therapy to combat depression in kids, to give them a safe and effective way to help combat the heavy burden of hopelessness and inertia that all - too - often accompany depression in youth.
One of the more unappealing potential side effects of testosterone therapy is gynecomastia.
It goes through in detail various potential sources of error and bias (e.g. manner and timing of reporting of weight, mammography, high risk vs average population, cancer subtypes, hormone therapies, etc) that may be confounding results, and relates results of previous studies to those of a more recent study which attempted to correct for some of these errors.
The past century has unveiled a plethora of preclinical data that has suggested the potential of a ketogenic diet as an aid in cancer treatment.7, 8 The benefits of a ketogenic diet, and dietary manipulation in general, may be a potent adjunct to current cancer treatments by synergistically working with chemotherapy and radiation therapy to starve cancer cells, leaving them more susceptible to damage from these treatments.7 - 10
Here you'll discover stories from the Special Yoga team and our practitioners that give you an insight into what we do and the wonderful community of people we support.We provide Special Yoga therapy to kids with special needs and offer certified teacher training to help more children embrace their potential Frequency about 2 posts per month Since Jan 2015 Website specialyoga.org.uk / blog + Follow Facebook fans - 12,504.
Here you'll discover stories from the Special Yoga team and our practitioners that give you an insight into what we do and the wonderful community of people we support.We provide Special Yoga therapy to kids with special needs and offer certified teacher training to help more children embrace their potential Frequency about 2 posts per month Since Jan 2015 Website specialyoga.org.uk / blog + Follow Facebook fans - 12,504.
In November in Albuquerque, NM, more than 60 participants attended this interactive panel «Art Therapy in Urban Settings: Problems, Potentials, Possibilities» that addressed the growing problems therapists and educators encounter in urban schools and regular / self - contained classrooms.
found that slightly more than a third of medical practices are effective or likely to be effective; 15 % are harmful, unlikely to be beneficial, or a tradeoff between benefits and harms; and 50 % are of unknown effectiveness...»... One surprising type of reversal we observed was potentially beneficial therapies being withheld because of unfounded concerns about their potential to cause harm.»
Personally, I have always seen therapy to be more of a intense joint partnership focused on a client's personal achievement, exploration of their untapped potential and opportunities and utilizing their strengths to balance them out.
Frequently, a client's current difficulties have developed over a long period of time, and during the course of therapy a deepened understanding of the roots of these problems increases a client's potential to experience positive change, increased self - esteem, strengthened confidence and more satisfying relationships.»
The struggle to meet the increasing demand for psychological therapies, particularly during financial downturns, has driven interest in how therapies can be delivered more efficiently and effectively.3 Computerised cognitive behaviour therapy (cCBT) is a rapidly advancing field that has been recommended within National Institute for Health and Care Excellence (NICE) clinical guidelines for depression.4 Proponents of cCBT have highlighted increased access for patients and the potential of these treatments to empower patients, 5, 6 while others have been sceptical that therapy can work in the absence of a therapeutic relationship with a professional.7
It prevents accurate monitoring of abuse potential, as the victim is likely to be afraid to report honestly if the potential is high, and it may cause more violence after therapy has stirred troublesome emotions and conversations or if the victim reports the abuser's actions honestly.