By uncovering the precise cellular mechanisms of nicotine's effect, this study suggests new and
more precise targets for drugs designed to block this powerful craving.
A group led by Chi - Huey Wong at National Taiwan University is continuing the work, finding nucleozin analogs and also finding
more precise targets within the nucleoprotein.
With an estimated 1 billion people worldwide suffering from some form of brain disorder, he argues, there is a very real need for new approaches, including optogenetics, to reveal
more precise targets in the brain.
«Discovering that these protein interact with other signals in preformed complexes gives
us more precise targets for medication development.»
These results significantly advance understanding of how cancer cells are made to move during metastasis and may provide
more precise targets for drugs to stop cancer metastasis in patients where there are oncogenic mutations.
More precise targets on the size and the valuations will be determined after the company begins talks with investors in coming weeks, said the people, who spoke on the condition of anonymity.
First, the pessimistic one outlined by Marshall Ganz in the early 1990s, suggesting that ever
more precise targeting of voters will narrow the electorate by leading campaigns to focus their efforts on fewer and fewer people leaving others outside the process.
Among their goals for this system are: a higher density electrode array to allow for
more precise targeting on neurons, new recording circuits that vastly increase the volume of data captured, and a new wireless power and telemetry technology that allows for real - time data transmission from the brain.
Next steps will include engineering T cells that reliably detect multiple features on cancers such as mesothelioma and glioblastoma, allowing for
more precise targeting of these diseases.
This allows for far
more precise targeting for those devastating headshots and darkness cloaking light shattering that are both so crucial to gameplay.
The more precise targeting options available to agents, the stronger a case Facebook can make to brokers that they should syndicate listings directly to Facebook.
Not exact matches
And in addition to the usual service fees, T - Mobile sees the possibility of selling TV ads using
targeting technology that is
more precise than what is possible through cable networks.
«Data and insight that comes directly from patient records — real - world evidence — is transforming how pharmaceutical and life science companies develop
more precise,
targeted therapies,» said Cota CEO John Hervey in a statement.
Perhaps their inability to believe Facebook on the matter is
more of an indication of how
precise — and downright creepy — Facebook's ad
targeting capabilities have become over the years.
Karri wrapped up by saying, «This new opportunity to get
more precise and
targeted with customers means that marketers have to act like scientists.
«I don't have a
precise target [for the new season] but I always want to improve, so I want to score
more goals than last year.
Today,
targeted chemotherapy and
more precise surgery means that
more breast cancer patients are surviving than ever.
As
more people spend
more time online, incredibly
precise online
targeting can yield higher returns with
more obvious direct engagement than traditional, broadcast - TV spending.
Neurons formed later are much
more precise in their
targeting.
«With further validation, this radiotracer could also potentially be used to perform
targeted biopsies for
precise tissue analysis, which could lead to earlier,
more appropriate treatment for prostate cancer patients.»
They give some clues about why these diseases occur, but
more detailed maps, such as this, will pinpoint where the problems lie — providing
precise targets for therapies.
«Future research into the role and function of vlincRNAs holds promise for both highly
targeted diagnostic tests and
more precise cancer treatments.
In doing so, they hope to contribute to the development of
more effective,
precise and
target - driven therapies to prevent heart disease in women.
IGRT is the process of using frequent imaging, typically performed in the treatment room prior to radiation delivery, throughout a patient's course of radiation therapy treatment to improve localization of the
target and normal structures, which allows for
more precise and accurate radiation delivery.
This process allows specialized Pac - Man — like brain cells called microglia to engulf the
targeted synapses, paving the way for
more precise brain wiring.
Newer,
precise methods which
target the dents in cancer's armoury provide fresh opportunities for better treatments to help
more people survive the disease.
Although doctors have long incorporated personal information like family history into treatment plans, personalized medicine holds the promise of revolutionizing medical care by using knowledge of molecular biology and genetics that will allow
more precise diagnoses, better diagnostic tests, greater predictability of disease course,
more successful therapies by
targeting the right treatments to the right patients, and improved patient safety by selecting drugs and their proper dosage to reduce adverse side effects.
After a good spam campaign, with a mix of pharmaceutical messages for a client, paid for in batches of a million and sent to a cheap, inferior list of addresses — and phishing messages for your personal profit, sent to a
more precise,
targeted list — you can come back to the market with
more data to sell, and
more money with which to buy work and data from the others.
A
more precise estimate of the antelope's range would help to
target conservation efforts, says Nicholas Wilkinson, a Vietnam - based wildlife ecologist at the University of Cambridge, UK, who is working with the conservation group WWF.
These characteristics mean that
precise and specific
targeting is valuable for ChemCam, and that the science mission would be enhanced by
more frequent observations — and these are things that AEGIS» autonomous intelligent
targeting can deliver.
The host star is bright (V = 11.2, J = 9.1) and so may be a good
target for
precise radial velocity... ▽
More We report the discovery of a Neptune - size planet (Rp = 3.0 Re) in the Hyades Cluster.
«By developing «new
targets of opportunity» to eradicate prostate cancers with PI3K gene pathway mutations, Dr. Hsieh's team is bringing us closer to
more potent and
precise solutions for currently treatment - resistant prostate cancer,» said Jonathan W. Simons, MD, president and CEO of the Prostate Cancer Foundation.
With highly
precise image - guided treatment delivery, we can
target the radiation on the tumor and avoid healthy tissue
more successfully than ever before.
«Shedding light on these pathways may help us to identify the various agents that precipitate disease as well as to design
more precise,
targeted treatments.»
Immune Design is a clinical - stage biotechnology company made up of collaborative, «can do», experienced professionals passionate about leveraging the company's leading - edge technologies that
target dendritic cells for a
more precise immune response for the treatment of cancer and other chronic conditions.
The accurate asteroseismic determinations now available for large number of stars in the Kepler fields can be used to check and calibrate surface gravities that are currently being obtained spectroscopically for a huge numbers of stars
targeted by large - scale spectroscopic surveys, such as the on - going Large Sky Area... ▽
More Asteroseismology allows for deriving
precise values of surface gravity of stars.
Specification now of a CO2
target more precise than < 350 ppm is difficult and unnecessary, because of uncertain future changes of forcings including other gases, aerosols and surface albedo.
In the meantime, our experience to date suggests that
precise genome editing of putative
targets in primary cell systems is possible, offering
more human disease relevant systems than conventional cell lines.
More precise assessments will become available during the time that it takes to turn around CO2 growth and approach the initial 350 ppm
target.
I am able to offer
more precise instruction, work with rehab clients and help clients
target specific muscle groups essential for their recovery and wellbeing.
In the future, he adds, a better understanding of the overlap between the two conditions could open the door to
more precise diagnoses, and therefore
more targeted treatment.
Over the years, I've perfected and modified the class, based on experience and current knowledge, resulting in an evolution of the class that has become
more precise and
targeted
Crosscutting between his protagonists in
precise, well -
targeted editorial volleys, with occasional flashbacks to their respective troubled childhoods, Metz shows how the cool, calculating Swedish stud and the foul - mouthed American hothead may have had
more inner demons in common than you might expect.
As a fast - moving creature trying to attack stationary
targets, you'd need a
more intuitive and
precise control scheme than what you'll find here.
The author suggests that in order detect differences in school quality, the evidence we gather must reflect the extent of student mastery of learning
targets that are much
more precise.
By designing the formative assessment around the learning
targets, the resulting information is much
more precise about what the student has / has not yet learned.
When resiliency data is integrated with attendance, behavior, and coursework (ABC) data, a picture of the whole student emerges and teachers can
more effectively
target interventions to the
precise issues that students are struggling with.
She described the kind of action steps she used to give before she started getting
more precise and
targeted — and what better action steps would look like.
What's the best way to support the overall learning and growth of children — via a healthy doze of generalized praise, or with a strict diet of
precise,
targeted feedback that helps children see their own work
more objectively?
So provided your
targeting is
precise enough, your copy is relevant, and your landing page is optimized to get
more conversions (and none of this is difficult to do), you can see some amazing results with a very low budget.»