Sentences with phrase «more uncertain environment»

This year, Labour, the Conservatives and the Liberal Democrats face a much more uncertain environment than in previous elections.

Not exact matches

The Trump administration fears a failure to obtain an agreement within several weeks would mean talks would drag into 2019 and into a more uncertain political environment.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Consumers are more hesitant to pull the trigger in an uncertain economic environment, and marketers are less confident of victory.

On the other hand, advanced maternal age is associated with a more stable family environment, higher socio - economic position, higher income and better living conditions, as well as better parenting practices, [14] but it is more or less uncertain whether these entities are effects of advanced maternal age, are contributors to advanced maternal age, or common effects of a certain state such as personality type.

In a fashion market being reshaped by digital media, rapid globalisation and an uncertain economic and geo - political environment, more and more brands are rethinking their approach to where, when and how to present their collections, putting pressure on traditional fashion weeks to evolve.

This creates uncertain demand for providers, and the move toward a more efficiently utilized information environment will have huge effects on all our familiar aggregations, packages, and delays.

In such uncertain environments, investors seek out companies with more predictability of earnings.

However, keep in mind the reason why P / E10 might have fallen to low levels in the first place: the economic environment was more uncertain than usual.

But if we really are facing into a far more uncertain low - growth environment, companies boasting high price or low cost moats are obviously best - equipped to thrive & deliver returns in a much harsher world.

Gallup's annual update on Americans» attitudes toward the environment shows a public that over the last two years has become less worried about the threat of global warming, less convinced that its effects are already happening, and more likely to believe that scientists themselves are uncertain about its occurrence.

Computer models of a warming climate indicate that conditions may become more conducive to severe thunderstorms in some regions.11 Thunderstorms provide a favorable environment for tornado formation; but tornadoes also require wind shear, a highly uncertain element in climate models.

Citing the structured environment, heavy emphasis on billable hours, and the long and uncertain path to partnership, associates ranked their satisfaction with the way they work and the rewards they receive lower than workers Read More...

Executives who are seeking more fulfillment and help in making strategic career moves; Professionals who are currently employed but seeking better jobs in an uncertain environment or those that have lost their jobs and are battling job competition.

«In this uncertain economic environment, today's global investors are looking for a much more defensive play,» says Coren.

In other words, under a narrow QM definition, lenders would further restrict home mortgage credit in what is already a tight lending environment because they would be fearful of the severe penalties that would be imposed if they failed to satisfy the ability - to - repay requirement under the more uncertain standards that would apply in the non-QM market.