It's probably a significant underestimate, since
most aneuploidies abort early in pregnancy.
Not exact matches
Aneuploidy (an abnormal number of chromosomes) is the
most common genetic alteration in human tumors and a major cause for birth defects (Figure 4).
Errors in chromosome segregation are a major cause for birth defects and embryonic lethality in humans, and the
most common genetic alteration in human tumors is aberrant chromosome numbers, called
aneuploidy.
Errors in chromosome segregation can cause birth defects and embryonic lethality in humans and cause
aneuploidy, the
most common genetic alteration in tumors.
Aneuploidy is found in
most solid tumours, but it remains unclear whether it is the cause or the consequence of tumorigenesis.