Sentences with phrase «most human cancers»

Not exact matches

When humans and even most fish are over-exposed to the sun's powerful rays they can fall victims to the dreaded growths and lesions of skin cancer.

'' «At PMV Pharmaceuticals, we are targeting the most frequently mutated gene in human cancer (p53) to make an unprecedented impact on cancer patients» lives.

If humans can easily shut an AI down, then the most effective means of curing cancer will be for it to research new medicines (which humans will support); if humans can no longer stop an AI, the most effective means of curing cancer is destroying humanity (since it will no longer matter that humans will fight back).

Indeed, the animal rights movement's fury against the speciesist use of animals» a necessary element for human flourishing, particularly in medical research» has increased to the point that scientists are now under threat of death by the most radical liberationists for daring to experiment on rats or monkeys to find cures for cancer and other human afflictions.

The U.S. Food and Drug Administration (FDA), the nation's chief food safety regulator, plans to start testing certain foods for residues of the world's most widely used weed killer after the World Health Organization's cancer experts last year declared the chemical a probable human carcinogen.

The field of cancer epigenetics was recently transformed by the finding that genes encoding for epigenetic regulators are among the most commonly mutated genes in human cancers.

«Almost every human being is infected with one or more of these viruses, but most people never develop symptoms, much less breast cancer,» Friedenson said.

Ironically, because of its pivotal role in coordinating a range of cancer - fighting mechanisms in the human body, it is also one of the most important cancer - causing genes when mutated.

Most animals lack the gene to convert omega - 6 fatty acids — which, when eaten in large amounts, contribute to heart disease, cancer, diabetes, and arthritis in humans — into healthier omega - 3s.

«Dirty bombs» strapped to listeria bacteria cleared tumours in mice with the most lethal human cancer

Depending on exposure, such contaminants can cause cancer and harm most human organs, and kill or sicken wildlife.

In contrast, viruses that cause cancer, such as the human papillomavirus that is responsible for most cases of cervical cancer, disrupt a cell's genome, thereby triggering out - of - control growth.

Most of the research on infusing cancer into humans is decades old.

Using both fruit fly and human lung cancer cell lines, researchers targeted two of the most common genetic mutations associated with NSCLC — Ras and PTEN (P13K).

Two other big initiatives fared better: a proteomics effort to identify proteins in blood and other biomarkers that might work as early warning signs of cancer, and the most recent: a human Cancer Genome cancer, and the most recent: a human Cancer Genome Cancer Genome Atlas.

Another factor is use of the human papillomavirus (HPV) vaccine, because HPV is a root cause of most cervical cancers.

The researchers further found that miR - 486 is itself regulated by the tumor - suppressor gene p53, the most frequently altered gene in human cancers, and that activity of miR - 486 is partially dependent upon functional p53.

A team of researchers, led by Keiko Kawauchi from the Mechanobiology Institute at the National University of Singapore, studied cells that had been transformed into cancer cells by Ras, the most common oncogene in human cancer.

All the fish had the human cancer mutation BRAFV600E — found in most benign moles — and had also lost the tumor suppressor gene p53.

The researchers, who reported their findings in a recent issue of BMC Complementary and Alternative Medicine, suggest that the findings could pave the way for clinical testing of the compounds on human colon cancer, which is the second most common cancer in women and the third in men.

They are made of amino acids, just as humans are, and because of their intimate relationship with our own biological molecules, they have the potential to fight some of the most intractable diseases, including cancer.

Ras is the most frequently mutated human cancer gene (oncogene), yet despite recent breakthroughs, therapeutic options to target Ras - dependent cancers remain limited.

The exact same dominant - negative mutations are among the most commonly observed mutations in human cancers.

In humans it's the most common lymphoma subtype while in dogs, it's one of the most common cancers in veterinary oncology.

«The LSC17 score is the most powerful predictive and prognostic biomarker currently available for AML, and is the first stem cell - based biomarker developed in this way for any human cancer,» says Dr. Wang.

Pancreatic cancer is one of the most aggressive human cancers — symptoms do not occur until the cancer is well advanced.

In previous studies, including recent genome sequencing of cancer patients, human SETD2 has been implicated in several cancer types, especially in renal cell carcinoma — the most common kind of kidney cancer.

A year later, Carlo Croce, now director of the Human Cancer Genetics Program at Ohio State University, reported that chronic lymphocytic leukemia (CLL), the most common form of the disease, was caused by deletion of two microRNA genes.

Nearly all cervical cancers are caused by HPV (human papillomavirus) infections, the most common sexually transmitted disease.

And with non-melanoma skin cancers being the most frequent human tumors, there is clearly a tremendous need to understand the underlying molecular mechanisms, to allow the development of drugs to treat these types of cancer.

Importantly it is also one of the most frequently activated genes in human cancer.

Although most of the work has been carried out using in vivo studies, Asst Prof Gasser has been collaborating with Dr Joanne Ngeow at the National Cancer Centre Singapore to characterise the process in different types of human tumours.

The company's thermal cyclers were used by every major genome centre during the sequencing of the human genome and were most recently used by the BC Cancer Agency during the sequencing of the SARS virus.

«One of the most common viruses in humans may promote breast cancer development: Findings could lead to new prevention strategies.»

Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States, as well as a cause of various cancers, and a new study published online by JAMA Oncology estimates the overall prevalence of genital HPV infection in men ages 18 to 59.

Ince and his team found that although TNBC lacks the three receptors that fuel most breast cancers — estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 — it does express androgen receptors (AR) and vitamin D receptors (VDR).

Cancer of the pancreas (scientifically known as pancreatic ductal adenocarcinoma or PaCa) is one of the most deadly forms of the disease in humans.

Until recently, researchers assumed that after human ancestors shed most body hair, sometime before 2 million years ago, they quickly evolved dark skin for protection from skin cancer and other harmful effects of UV radiation.

They immunized them with the antigen α - fetoprotein, which is found in 70 - 80 percent of human liver cancers, and serves as both a biomarker for diagnosing and a target for treating the sixth most common cancer worldwide, He says.

The scientists took the genes for the most effective liver cancer antigen receptors on those T cells, put those receptors on human T cells and the resulting engineered human T cells eradicated the cancer as well, without hurting normal liver cells, they report in the journal Hepatology.

Unlike most cervical cancers — which are primarily driven by human papillomavirus — this subtype is initiated by the virus, but HPV oncogene expression eventually disappears and does not sustain the cancer's growth.

Telomerase is turned off in most human cells, but cancer cells often must reactivate it so that they can keep dividing like crazy.

Dr. Keerti Shah's most - cited paper with 1,468 cites to date: Walboomers JMM, et al., «Human papillomavirus is a necessary cause of invasive cervical cancer worldwide,» J. Pathol.

But while most PDX mice are used as general models of human cancer in the laboratory, others seek to use them as Fiebig originally hoped — as avatars to guide customized patient care.

Daniel E. Speiser and coworkers demonstrate that human cancer - specific cytotoxic CD8 T cells are strongly activated after vaccination with peptides and CpG oligonucleotides, representing the currently most powerful synthetic cancer vaccine formulation.

«It's probably the single most common gene fusion in human cancer,» said study co-leader Antonio Iavarone, MD, professor of neurology and of pathology and cell biology (in the Institute for Cancer Genetics) atcancer,» said study co-leader Antonio Iavarone, MD, professor of neurology and of pathology and cell biology (in the Institute for Cancer Genetics) atCancer Genetics) at CUMC.

Reykjavik, ICELAND, 25 September 2011 — Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome associated with risk of developing basal cell carcinoma of the skin (BCC), as well as prostate cancer and glioma, the most serious form of brain cancer.

Our technological expertise ranges from the most fundamental approaches to study membrane transport in lymphocytes and dendritic cells (subcellular compartmentalization, intravital microscopy, phagosomal functions), the systematic analysis of gene expression and it regulation (RNAseq, Chip Seq, proteomics) and physiological and pathological immune responses (mouse models for cancer immunity, immunomodulation / vaccination, human clinical studies in cancer).

LA JOLLA — The Salk Institute, which hosts a National Cancer Institute (NCI)-- designated cancer center and Indivumed GmbH, a world leading cancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in cCancer Institute (NCI)-- designated cancer center and Indivumed GmbH, a world leading cancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in ccancer center and Indivumed GmbH, a world leading cancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in ccancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in ccancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in cancercancer.

Unlike previous MRI studies of tumors in mice, the researchers were able to detect very small naturally occurring cancers, which were excellent models for human breast cancer; the tumors the mice developed were «realistic models of the most frequently detected human cancers,» the authors wrote.