That's where
most human variation occurred.
Not exact matches
The
most prescribed types of insulin are called analogues, which are slight
variations of
human insulin that aim to help diabetics» bodies function more closely to how they would if they were able to produce the insulin themselves.
With
variation, but in essential correspondence of members of the plot, it happened of course throughout the spreading
human family in the centuries and years, perhaps even months or days, preceding; and it has
most assuredly continued to happen, in its significant essence, with persistence and always accompanying
human carnage down to our own time and decade and, who knows, even day and hour.
They derive from some of the
most basic approaches to the riddle of
human existence imaginable, Each of these options and their
variations have sustained and continue to sustain vast segments of the
human population in their attempts to cope with life and death, and are living options today.
The
most comprehensive child care study conducted to date to determine how
variations in child care are related to children's development, supported by the National Institute of Child Health and
Human Development (NICHD), found that the more hours children spend in child care, the higher the incidence of problem behavior and the greater its severity.
Given Britain's involvement in an international research consortium formed to create the
most detailed and medically useful picture of
human genetic
variation to date, tonight's other discussion points include the scientific value of the information and the regulatory implications of providing public access to personal genome data through academic research projects, as well as through commercial organisations.
Single - nucleotide polymorphisms (SNPs — pronounced «snips») are the
most common type of
human genetic
variation; each one represents a small difference in a nucleotide — the building blocks of our DNA.
The agency then lowers that dosage by a factor of 10 to account for possible
variations in response between the
most sensitive test animal and
humans.
Researchers have discovered that protection from the
most severe form of malaria is linked with natural
variation in
human red blood cell genes.
While
most loggerhead nesting
variation appears to be natural, Van Houtan insists that
humans bear a good share of the blame.
The 1000 Genomes Project, established in 2008, is an international research effort to establish the
most detailed catalog of
human genetic
variation.
A unifying theme in their research is that the
human is the
most complex, fascinating and important system in which one can study the effects of heritable
variation.
But Dr. David Goldstein, director of Duke University's Center for
Human Genome
Variation, says, «Right now we know very, very little of the genetics of the diseases that
most people will get.»
Not so long ago, there was a hope in the research community that common genetic
variation, i.e. variants present at minor allele frequencies > 5 % in
human populations, might explain
most or all of the heritability of common complex disease.
Most of that is by design: the 1,000 Genomes Project generated and made available sequence data for more than 1,000 individuals in an effort to further characterize
human genetic
variation.
With more than 15 million entries in dbSNP, single nucleotide polymorphisms (SNPs) remain the
most common form of DNA sequence
variation in
humans.
Scientifically, the meteorologists, climatologists, and atmospheric physicists, who were responsible for «discovering» the
human contribution to the terrestrial greenhouse effect, have been the
most consistent champions of its importance, while the solar physics community, and especially those interested in solar - terrestrial relations, have increasingly stressed the possible importance of the long - term
variations of the solar constant as the chief cause of climate change.
Furthermore, studies have demonstrated that modern
human variation is generally continuous, rather than discrete or «racial,» and that
most variation in modern
humans is within, rather than between, populations [11], [17].
Human genetic studies have identified novel DNA
variations in the genome associated with AMD, but
most of them are not located within gene protein - coding regions, making their study a challenge.
Most of us
humans learn pretty quickly what each individual
variation on the demanding meow means.
But if they can be linked to warmer conditions globally, then these would be
most likely caused by solar
variations or cosmic rays, a recovery from the LIA and certainly not due to increases in CO2 levels, which aren't caused by
human emissions anyway.
Hypothesis 2b: Although the natural causes of climate
variations and changes are undoubtedly important, the
human influences are significant and are dominated by the emis - sions into the atmosphere of greenhouse gases, the
most important of which is CO2.
... incomplete and misleading because it 1) omits any mention of several of the
most important aspects of the potential relationships between hurricanes and global warming, including rainfall, sea level, and storm surge; 2) leaves the impression that there is no significant connection between recent climate change caused by
human activities and hurricane characteristics and impacts; and 3) does not take full account of the significance of recently identified trends and
variations in tropical storms in causing impacts as compared to increasing societal vulnerability.
«While these increases are
most likely due to Earth's changing climate, uncertainty exists as to whether they are the product of
human - induced greenhouse warming or represent
variations related to natural multi-decadal climate cycles,» Ruggiero's study said.
Pure speculation, since even the
most sophisticated climate models still can't tell the difference between
human - caused and natural
variation.
The 10 - year period ending in 2007 witnessed fewer severe cold snaps than any other 10 - year period since record keeping began in 1895.2 These changes can not be explained by natural
variation, and correspond very well with computer simulations that include
human influences on climate.3 Snow cover has decreased in
most regions, especially in the spring, and mountain snowpack has also decreased in several regions.4
Although natural
variations in the solar output can explain
most of the temperature
variations over the past centuries, it appears that global warming by heat - trapping gases, emitted by
human activity, is required to explain the sharp rise in global temperatures during the 1990s.
Hypothesis 2b: Although the natural causes of climate
variations and changes are undoubtedly important, the
human influences are significant and are dominated by the emissions into the atmosphere of greenhouse gases, the
most important of which is CO2.
The
most comprehensive child care study conducted to date to determine how
variations in child care are related to children's development, supported by the National Institute of Child Health and
Human Development (NICHD), found that the more hours children spend in child care, the higher the incidence of problem behavior and the greater its severity.