Sentences with phrase «most noncoding»

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Other researchers have found that more than 30 percent of long noncoding RNAs — which carry out several different jobs in the cell, most still unknown — are repurposed transposable elements (SN: 12/17/11, p. 22).
Most of the mutations identified in the new work land in genes, but some affect noncoding regions of the genome.
To provide a molecular basis for understanding N - CAM function, the complete amino acid sequences of the three major polypeptides of N - CAM and most of the noncoding sequences of their messenger RNA's were determined from the analysis of complementary DNA clones and were verified by amino acid sequences of selected CNBr fragments and proteolytic fragments.
This, in my opinion, is one of the most compelling parts of this study: in vivo functional validation of a single base change in a noncoding enhancer that's hundreds of thousands of bases away from the gene it regulates.
And let's face it, exome sequencing lets us conveniently avoid some of the most challenging aspects of human genomics, like detecting complex rearrangements (SVs) and interpreting noncoding regulatory variants.
Many, if not most of the genomic loci associated with human traits lie in noncoding regions.
Integrating this new information into computational models, my colleagues and I predicted that about 5 percent of HARs function as noncoding RNAs, while most are enhancers that control gene expression during embryonic development.9
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