Sentences with phrase «most of the gene activity»
These sequences in our DNA are often situated far away from the actual genes they regulate, in comparison to so called promoter regions, which traditionally have been considered to control most of the gene activity.
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«Our stem cell - based studies indicate that low - calorie sweeteners promote additional fat accumulation within cells compared with cells not exposed to these substances, in a dose - dependent fashion — meaning that as the dose of sucralose is increased more cells showed increased fat droplet accumulation,» said Sabyasachi Sen, M.D., Associate Professor of Medicine at George Washington University in Washington, D.C. «This most likely occurs by increasing glucose entry into cells through increased activity of genes called glucose transporters.»
Most research on epigenetics has focused on the way everyday experiences alter patterns of gene activity in DNA during life through a chemical process of gene tagging called methylation, which usually silences genes.
Most genes have hundreds of such sequences, with varying activity and uniqueness in the genome.
The researchers further found that miR - 486 is itself regulated by the tumor - suppressor gene p53, the most frequently altered gene in human cancers, and that activity of miR - 486 is partially dependent upon functional p53.
«We identified, across the genome, that enhancer RNAs were the most common type of RNA that bound to CBP, and that by making this interaction, eRNAs play a crucial role in regulating CBP activity and gene expression.»
«Our team studied thousands of molecular clues in each of these samples, sifting through extensive data on the activity of genes, proteins and other molecules to identify those of most interest,» says Katrina Waters, a biologist at PNNL and a corresponding author of the study.
«Our team studied thousands of molecular clues in each of these samples, sifting through extensive data on the activity of genes, proteins, and other molecules to identify those of most interest,» said Katrina Waters, the leader of the PNNL team and a corresponding author of the paper.
«But perhaps the most exciting implication is that our tools, when paired with appropriate activity modulator genes, could enable non-invasive deep brain modulation for the treatment of neurological diseases such as Parkinson's disease.»
As was done with Dolly, they first deprived those cells of nutrients to shut down cell division and most gene activity.
«For the first time, we can provide a complete description of an animal model from genes to behavior — including at the level of neuronal network activity, which has been ignored in most studies to date.»
One extension of MRI called functional MRI can spot which brain areas are most active, but until now there hasn't been a high - resolution method for detecting enzyme activity — essentially a measure of what genes are turned on inside a cell.
Most of those mutations are probably benign, but some may alter a protein's structure and function, or interfere with gene activity, leading to disease.
Most coveted by the firms are automated systems for analyzing the activities of tens of thousands of genes and proteins in normal and diseased cells.
In the current study, prediction analysis of gene expression data was implemented in order to identify the genes that are most useful to determine the state of cyclic changes in locomotor activity.
Clock genes are extremely influential, affecting the activity of most other genes in the body in one way or another.
Then, by comparing this ancient epigenome with that of modern humans, they identified genes whose activity had changed only in our own species during our most recent evolution.
UM270 was the only strain possessing genes involved in the synthesis of indole -3-acetic acid (IAA), the most common auxin, and phenylacetic acid (PAA), also known for its antimicrobial activity (23).
Noise has traditionally been difficult to study in biology, because most biological techniques, such as measurement of gene activity, average the output of many cells, erasing individual variability.
Test each mutant mouse line (4,000 mouse lines in the first 5 years, and ultimately up to 20,000) through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human diseases.Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems.
Most recently, research has shown that a certain set of these microbes may actually influence the activity of genes in your brain — and the parts they play are not small parts.
Schools can sign up via the website and will receive free educational materials tailored to early years and all key stages, which have been designed to help schools make the most of their Jeans for Genes Day activities, plus toolkits, assembly and fundraising ideas and event check lists.