Sentences with phrase «most timely ways»

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These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits
Governor Aregbesola who tagged his speech «a timely partnership» said IITA has been very supportive of the state's flagship agriculture programme most significantly on Osun Rural Enterprise and Agriculture Programme (O'REAP) in many ways.
There is a bipartisan political consensus that the country needs more tech - savvy workers, they say, and Question No. 12 is the most comprehensive, timely, and cost - efficient way to collect the data that policymakers need to achieve that goal.
Most common, though, were glitches in getting test results to the doctor in a timely way (or at all).
In case you don't figure out that this story is meant as timely political allegory, there are bill - boarded hints along the way, the most obvious including Kemp holding forth on Nixon's legacy and the despoliation of Paradise.
«Selma»: Despite a few flaws — the film's final act meanders briefly before finding its way to a powerful climax — director Ava DuVernay's all - too - timely portrait of Martin Luther King Jr.'s influential (and dangerous) civil rights march in Alabama contains some of the most powerful moments I saw in any movie this year.
Its solution is found most often in creating a positive, supportive school culture and climate, where teachers are treated as professionals and given the opportunity to collaborate, problem solve, and get needed, reasonable supports in timely ways.
One of the most important ways to ensure the efficient, timely delivery of training is by using the right Learning Management System (LMS).
Most of my purchases end up on Craigslist or eBay in a timely way, and if I'm nimble enough I can recover 80 or 90 percent of my investment or maybe break even, particularly if I swooped in earlier at a sale.
So, if you are looking for the most quality - driven, timely help for assignment writing in ATHE courses, you must contact our customer support representative today and change the way you score in your assignments forever.
To improve your credit score under most systems, focus on paying your bills in a timely way, paying down any outstanding balances, and staying away from new debt.
While the goal may be to find an out of state home in the most timely, cost - effective way, remember it's a major investment that you don't want to cut corners with or rush through without due diligence.
Most, if not all, titans in business and philanthropy amassed their wealth through the timely development of a product or service or the old fashioned way: inheritance.
Thousands of players taxing the servers, experimenting with gameplay systems and reporting what they find (or not — most developers can monitor metrics from your game, even if you don't specifically report anything) is one of the best ways for developers to patch issues in an efficient and timely manner.
NativeEnergy establishes a timeline for each stage of the project's development to ensure the project is built in the most efficient way and carbon offsets can be realized in a timely and sustainable manner.
The second project, carried out by IRENA, analyses various design options of the auction scheme and focuses on presenting lessons learnt and best practices on how governments can design and implement auctions in the most cost efficient way while ensuring that projects awarded come online in a timely manner.
His approach is flexible, but will often involve early in - depth analysis of the strengths, weaknesses, risks and opportunities involved; assisting in formulating an appropriate strategy; supporting dispute resolution in the most suitable way (including negotiation, mediation, arbitration and litigation); and providing timely and incisive advice on key issues arising in a dispute or potential transaction.
A life care planner can communicate with court officials to have this done in the most practical and helpful ways, and can then supervise the spending to make sure it is economical and timely.
Our experienced divorce lawyers at Fine & Associates Professional Corporation will guide you through the divorce process in the most timely and affordable way possible while advocating for you during your time of need.
Just be sure that you gather all of the information you can and present it to your Midland provider in the most accurate and timely way possible.
Most efficient way to accomplish traffic school in a timely manner.
Choosing divorce mediation offers a way for both parties to move forward in the most timely and fair process.
From all of it I have gleaned the most important point in this very timely article: that as the new salesperson YOU are interviewing the BOR, not the other way around.
We strive to provide timely & detailed reports to our clients in the most efficient ways possible.
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