Using a 10 % cutoff for positivity,
most tumors expressed p - mTOR, p - p70S6K, and p - rpS6 (C) and all 31 tumors expressed p - 4E - BP1 and total eIF4E (D).
Not exact matches
Kaplan - Meier analysis demonstrated that
most of the mice injected with cells
expressing wild - type PREX2 or GFP exhibited
tumor - free survival for more than ten weeks.
Here, we tested whether human gastric cancers, which are among the
most aggressive
tumor entities,
express the cellular receptor of Shiga toxin, the glycosphingolipid globotriaosylceramide (Gb3 / CD77).
In our
most advanced ZVex - based product candidate, CMB305, the vector carries the RNA for a
tumor antigen called NY - ESO - 1 that is
expressed in a wide range of
tumors.
Since the discovery that telomerase is repressed in
most normal human somatic cells but strongly
expressed in
most human
tumors, telomerase has become a target for therapeutic agents to combat human cancer.