The most vulnerable cells in HD are brain cells called neurons, about half of the cells in the adult brain.
Not exact matches
«We suspected that the young are
most vulnerable because of their immature immune systems, but we didn't have a lot of hard evidence to show that before,» said study lead author Bo Hang, a Berkeley Lab staff scientist who previously found that thirdhand smoke could lead to genetic mutations in human
cells.
By hitting breast cancer
cells with a targeted therapeutic immediately after chemotherapy, researchers from Brigham and Women's Hospital (BWH) were able to target cancer
cells during a transitional stage when they were
most vulnerable, killing
cells and shrinking tumors in the lab and in pre-clinical models.
By hitting breast cancer
cells with a targeted therapeutic immediately after chemotherapy, researchers were able to target cancer
cells during a transitional stage when they were
most vulnerable.
In a continuation of this work, Goldman is also using mathematical modeling to pursue the
most effective dose of chemotherapy to induce the
vulnerable transition state of the cancer
cell demonstrated in this research.
Among the compounds
most vulnerable to attack by free radicals are the polyunsaturated fatty acids (PUFAs) vital to the structure and function of
cell membranes.
Thus, Tomasetti and Vogelstein reasoned, the tissues that host the greatest number of stem
cell divisions are those
most vulnerable to cancer.
The new study revives suspicions that adenoviruses cause an immune «own goal», priming people's immune systems to produce CD4
cells — the very
cells that HIV prefers to infect — and, worse still, to direct those
cells to the parts of the body that are
most vulnerable to the virus during sex.
Paradoxically, the exception is at the very moment when chromosomes are
most vulnerable, when they physically separate into two
cells at
cell division (mitosis).
These studies show that the DNA found inside mitochondria, the cellular structures whose job is to provide
cells with energy, is particularly
vulnerable,
most probably because they handle oxidative chemical reactions.
Using specific, known types of
cells allowed the researchers to see where the developing brain is
most vulnerable, Song says.
The
cells that are
most vulnerable to this process are muscle - related sensory neurons whose degeneration leads to the first symptoms of the disease.
These range from visual stimulation experiments that allow us to tap into the specific sets of retinal ganglion
cells that are
most vulnerable early in the disease, to the evolution of new imaging techniques, largely thanks to Alf Dubra and Vivek Srinivasan's work in those areas, and the ability to image retinal ganglion
cells and their component parts like their axons which degenerate very early in glaucoma.
This is
most commonly due to occlusion (blockage) of a coronary artery following the rupture of a
vulnerable atherosclerotic plaque, which is an unstable collection of lipids (cholesterol and fatty acids) and white blood
cells (especially macrophages) in the wall of an artery.
Endothelial
cells line the walls of the body's entire circulatory system, from the arterial walls of the heart to the smallest,
most vulnerable capillaries — and their role in heart health is critical.
The
cells are the
most vulnerable to cancer and other diseases during the
cell division process.
The diet that has been consistently promoted by the Weston A. Price Foundation meets the key criteria for offering the
most support for the integrity of the
cells vulnerable to injury through bombardment by modern energetic frequency fields.
«Personal responsibility for putting down that
cell phone is a good first step — but we need everyone to do their part, whether it's helping pass strong laws, educating our youngest and
most vulnerable drivers, or starting their own campaign to end distracted driving.»