A high proportion of
mothers of both microcephaly and non-microcephaly babies also tested positive for another mosquito - borne virus, dengue fever, as well as other infections such as herpes, rubella and toxoplasma.
Not exact matches
One
of the reasons it's been so troubling is that it's a cause
of a serious birth defect called
microcephaly, in which the head
of babies whose
mothers have been infected with Zika during pregnancy are abnormally small.
One reason Zika is troubling is that it is a cause
of birth defects, including
microcephaly — a condition where the baby's head is abnormally small — in babies whose
mothers have had Zika.
One reason Zika is troubling is because it is a cause
of birth defects, including
microcephaly — a condition where the baby's head is abnormally small — in babies whose
mothers have had Zika.
After taking samples and conducting brain scans, the researchers found that 41 percent
of mothers of babies with
microcephaly tested positive for Zika infection in blood or cerebrospinal fluid samples, compared with none
of those whose babies did not have
microcephaly.
The connection between Zika and
microcephaly first came to light last fall in Brazil, which has now confirmed more than 1,800 cases
of microcephaly that it considers to be related to Zika infection in the
mothers.
Mothers and families
of infants born with congenital anomalies (e.g.
microcephaly) should be supported to breastfeed their infants in line with WHO recommendations.
The finding strengthens the evidence that a
mother's Zika infection during pregnancy raises her baby's risk
of microcephaly and other brain malformations.
Neither set
of pups developed
microcephaly, which Diamond says could be because the researchers infected the
mothers so early during pregnancy that not much brain development had yet occurred.
In Brazil, thousands
of babies have been born with
microcephaly after their
mothers were infected with Zika virus.
Researchers have linked Zika virus to
microcephaly — a birth defect affecting the heads and brains
of infants born to infected
mothers.
The finding
of virus in the brain could also be important, since the most devastating impact
of the current outbreak in Brazil appears to be children
of infected
mothers born with
microcephaly — abnormally small heads and, in some cases, incomplete brain development.
«As we learn more about the consequences
of Zika infection, including the recent revelation that babies
of Zika - infected
mothers who had normal head sizes at birth have been diagnosed with
microcephaly months later, it is vital that we know this enemy and remain vigilant in protecting ourselves,» Diaz concludes.
Although Brazil has had more than 4000 suspected cases
of microcephaly, it has confirmed only 270 cases
of this brain - damaging condition in children born to
mothers who had evidence
of having been infected with the virus.
Data from the Brazilian metropolis have confirmed this suspicion and, together with other studies, enable the researchers to estimate the absolute risk
of microcephaly upon infection
of the
mother during pregnancy: approximately one out
of 100
mothers infected during early pregnancy will bear a child with
microcephaly.
«The increased number
of newborns with
microcephaly observed during the Zika outbreak in Brazil is linked to Zika infection
of the
mother during early pregnancy,» explains Drexler.
Since 2016 thousands
of children across South America have been born with
microcephaly, which causes abnormally small heads, after their
mothers became infected with the Zika virus during pregnancy.
We next estimated the maximum number
of births potentially affected by ZIKV in Latin America, as this region is the focus
of the recent outbreak and the first to point to a possible association with
microcephaly in newborn infants to
mothers infected with ZIKV.
Contracted through the bite
of an infected mosquito or through sexual or other modes
of transmission, Zika virus (ZIKV) infection can be prenatally passed from
mother to fetus.1 The virus was first identified in the region
of the Americas in early 2015, when local transmission was reported in Brazil.2 Six months later, a notable increase in the number
of infants with congenital
microcephaly was observed in northeast Brazil.3, 4 Clinical, epidemiologic, and laboratory evidence led investigators to conclude that intrauterine ZIKV infection was a cause
of microcephaly and serious brain anomalies.5 - 7 However, as with other newly recognized teratogens, these features likely represent a portion
of a broader spectrum.
The FBDS phenotype has been reported in an infant with laboratory - confirmed ZIKV infection, 13 in a neuroimaging report documenting cranial bone collapse in infants born to
mothers with suspected ZIKV infection during pregnancy, 14 and a recent case series
of infants with probable ZIKV - associated
microcephaly.38 In 3
of the largest case series reporting 35, 48, and 104 infants primarily with suspected congenital ZIKV infection, 33,37,38 approximately two - thirds
of infants had severe
microcephaly.
«We are also launching further studies to determine whether children who have
microcephaly born to
mothers infected by the Zika virus is the tip
of the iceberg
of what we could see in damaging effects on the brain and other developmental problems.»
«Among infants
of mothers exposed to Zika virus during pregnancy, the absence
of microcephaly at birth does not rule out congenital Zika virus infection or the presence
of Zika - related brain abnormalities,» according to a news release from the U.S. Centers for Disease Control and Prevention.
Expectant
mothers are most at risk because
of Zika's known link to birth defects (especially
microcephaly, where a baby's head is smaller than normal at birth).