Sentences with phrase «motor neuron degeneration»
Columbia University Medical Center (CUMC) researchers have identified a gene, called matrix metalloproteinase - 9 (MMP - 9), that appears to play a major role in motor neuron degeneration in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
sciencedaily.com
«These defects might lead to the symptom of motor neuron degeneration in SMA,» says Ma.
«That investigation showed that eliminating the gene for membralin leads to rapid motor neuron degeneration, but its cellular function wasn't clear.»
«Brain immune system is key to recovery from motor neuron degeneration: Results in study point to new approaches for ALS therapy.»
OBJECTIVES Amyotrophic lateral sclerosis (ALS) is a fatal disease characterised by combined upper and lower motor neuron degeneration.
For three years now we have been working on human cell models of rare neurodegenerative diseases with special emphasis on neuroacanthocytosis, neuronal ceroid lipofuscinosis as well as motor neuron degeneration (using iPS cells).
The spirulina supplemented mice had reduced motor neuron degeneration and inflammatory markers over the 10 week period.
The article examines the onset of motor neuron loss in a mouse model of SMA and sheds light on the pathophysiological mechanisms of motor neuron degeneration.