Sentences with phrase «mouse and humans»

The Core provides equipment and services to determine gene expression patterns in mouse and human tissues.

The system is effective in both mouse and human cells as well as in mouse embryos.

The researchers followed up with an analysis of mouse and human brain samples.

Scientists aren't always thinking about the genetic differences between mice and humans because they're focused elsewhere.

Using the information provided in this article, calculate the number of mouse and human genes that are the same or similar.

The study was conducted using mice and human stem cells.

The Core provides essential infrastructure, training, and support to scientists who want to use mouse and human stem cells in their research.

Because mice and humans share many genes, the research could shed light on the effects of low - dose radiation on people.

Our studies were performed using mouse and human immune cells and included cell lines, primary cells and expanded primary cells providing robust results.

When the researchers compared the timelines for mice and humans, the waves of microbes matched closely.

This factor is the first lung molecular marker during mouse and human development and is essential for lungs to mature properly in an embryo.

Tests have shown that mice and humans who lack these genes develop hair loss.

Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes.

The team further tested the probe in mice and human serum and report that it performed as expected.

The clinical applications are much more remote, because mouse and human germs cells develop differently and may require different conditions.

Scientists think that what they learn by studying mouse brown fat might not be applicable to people because mouse and human brown fat are at different locations.

Depending on results from further behavioural studies in mice and humans, the abnormalities could then be treated in parallel with seizures.

Beta - amyloid protein is found in the brains of mice and humans.

Although much similarity exists, mouse and human gene expression differs significantly in specific biological pathways.

This consortium selected 44 separate sections of the genome that included regions of high to low gene density and high to low similarity between mouse and human.

While the digestive systems of mice and humans are similar, there are important differences.

When testing the system, the scientists were able to detect movement in items such as bacteria, yeast, mouse and human cells.

Their findings — reported by the mouse ENCODE Consortium online Nov. 19, 2014 (and in print Nov. 20) in four papers in Nature and in several other publications — examine the genetic and biochemical programs involved in regulating mouse and human genomes.

Levels of the erythropoietin - responsive hormone erythroferrone in mice and humans with chronic kidney disease

Research shows there are substantial differences in the physiological actions of leptin in mice and humans [Ahima RS, 2000], which could explain why there are so many confusing theories about leptin in the diet industry.

Indeed, when the researchers engineered connective tissue cells from mouse and human skin to produce PRDM16 and C / EBP - beta, they became fully functional brown fat.

Using cells from mice and human livers, Toronto General Hospital Research Institute researchers demonstrated for the first time how under specific conditions, such as obesity, liver CD8 + T cells, white blood cells which play an important role in the control of viral infections, become highly activated and inflammatory, reprogramming themselves into disease - driving cells.

The IGF1 protein is crucial for the growth of mammals, including mice and humans, so Ostrander's group and other collaborators began collecting DNA from additional breeds to see if they also shared the same gene variant.

In a new study, published 11 August in Science, researchers classified neurons from mouse and human brain tissue by their methylation patterns.

But pre-op chemo can, instead, promote metastasis, scientists concluded from experiments in lab mice and human tissue, published in Science Translational Medicine.

As mice and humans age, levels of that protein circulating in the blood rise, Alzheimer researcher Tony Wyss - Coray at Stanford University and colleagues found.

When they analyzed microbes found in fecal samples collected from mice and humans at different times of day, they discovered rhythmic fluctuations in the abundance of microbes and their biological activities.

One researcher, Esposito, is doing just that comparing mice and human infants.

Another flurry of work, this time involving many laboratories, turned up mouse and human forms of tim in 1998.

This is the finding of a study in both mice and human patients led by researchers at NYU Langone Medical Center and published online June 9 in the journal Cell.

An exciting moment for Hochedlinger came when Ph.D. student Nimet Maherali generated mouse and human iPS cells in the lab for the first time.

By examining the results of genome - wide association studies (GWAS) in conjunction with experiments on mouse and human red blood cells (RBCs), researchers in the lab of Whitehead Institute Founding Member Harvey Lodish have identified the protein cyclin D3 as regulating the number of cell divisions RBC progenitors undergo, which ultimately affects the resulting size and quantity of RBCs.

Upon further investigation, they found that a tumour - suppressor gene called alternative reading frame (ARF), which is normally suppressed in mouse and human iPSCs, remained active in the mole - rat iPSCs.

In marked contrast to the widely held notion that the insulin - producing pancreatic beta cell loses function with wear and tear, the researchers now show that mouse and human beta cells are fully functional at advanced age.

Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, Wang S, Fortier M, Greenberg AS and Obin MS. «Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans.»

The tag allowed scientists to see bacterial invaders in live mice and human cadavers.

Ultimately, Godwin would like to understand why macrophages produced by adult mice and humans don't suppress scarring in the same way as in axolotls and then identify molecules and pathways that could be exploited for human therapies.

These diverse, small RNA molecules, known as Piwi - interacting RNAs (piRNAs) are produced by various animals, from insects and worms to mammals like mice and humans.

Oct4, Sox2, c - Myc, and Klf4 were the four original factors that were capable of converting mouse and human fibroblasts into iPs cells [1], [3], [5], [11], [12].