Sentences with phrase «mouse brain and spinal»

The mouse model mimics aspects of the infection in humans, with high levels of the virus seen in the mouse brain and spinal cord, consistent with evidence showing that Zika causes neurological defects in human fetuses.

Not exact matches

In this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cells.

Working primarily with mice, senior author and University of Virginia neuroscience professor Jonathan Kipnis and his group identified a hitherto undetected network of lymphatic vessels in the meninges — the membranes that surround the brain and spinal cord — that shuttle fluid and immune cells from the cerebrospinal fluid to the deep cervical lymph nodes in the neck.

The researchers took immune cells isolated from paralyzed mice that specifically target and harm the brain and spinal cord, and treated them with either CBD or THC.

In a new study published in the Journal of Neuroimmune Pharmacology, Drs. Ewa Kozela, Ana Juknat, Neta Rimmerman and Zvi Vogel of Tel Aviv University's Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases and Sackler Faculty of Medicine demonstrate that some chemical compounds found in marijuana can help treat MS - like diseases in mice by preventing inflammation in the brain and spinal cord.

For example, it could be used to image neurons in living mice by combining the Raman scattering technique with existing methods in which tiny windows are implanted in the brains and spinal cords of laboratory animals.

Scientists at the Science Foundation Ireland - funded APC Microbiome Institute at University College Cork, Ireland, have shown that, at least in mice, gut bacteria play a key role in regulating abdominal pain and its associated changes in the brain and spinal cord.

In addition to suffering from a host of other problems like an abnormally large accumulation of this spinal fluid in the brain, these mice developed new neurons that did not have a clear sense of direction, pointing and moving in multiple orientations.

Furthermore, EV71 - infected mice given Roc - A lived longer than untreated mice and had lower levels of the virus in their spinal cord and brain.

Scientists at Prothena had confirmed that several of their candidate antibodies were able to clear AS pathology out of the brains and spinal cords of mouse models of PD and related disorders, substantially shielding them against the PD - like motor and cognitive impairments suffered by their untreated cousins.

As will be reported at the upcoming FSMA - sponsored 11th Annual International SMA Group Meeting in June, our compounds prolong survival in mouse models of SMA and are very effective at crossing the blood brain barrier to reach motor neurons in the spinal cord.

Dr. Akassoglou and her team reached this conclusion by using advanced imaging techniques to monitor the disease's progression in the brain and spinal cord of mice modified to mimic the signs of MS. Traditional techniques only show «snapshots» of the disease's pathology.

B or AAV9 (as a control) into different adult mice and after three weeks used the amount of green fluorescence to assess the efficacy with which the viruses entered the brain, the spinal cord, and the retina.

It includes a collection of pictorial gene expression maps of the brain and spinal cord of the mouse.

Upon re-feeding, new progenitor stem cells were created that repopulated the immune systems of the affected mice, and aided in repairing the damage to the brain and spinal cord.