Sentences with phrase «mouse brain pathways»

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In April, researchers led by Hongkui Zeng of the Allen Institute for Brain Science in Seattle assembled the first road map of neural pathways — called a connectome — inside the mouse brain (lBrain Science in Seattle assembled the first road map of neural pathways — called a connectome — inside the mouse brain (lbrain (left).

These mouse brain cells were treated with both the polymer and glowing dyes to help researchers pinpoint individual cells and trace neural pathways.

Comparing how this simple neural pathway changes between baby and adult mice sheds light on how brains rewire over time, Lichtman says.

Dias and Ressler probed the Notch pathway because they were examining many genes that are activated in the brains of mice after they learn to become afraid of a sound paired with a mild foot - shock.

What was especially «exciting» about this finding, he says, is that these variations were near a neural highway that previous studies have shown helps regulate life span in worms and flies, and that stopping chemical signals from this brain pathway extends the life span of mice.

In earlier research, they found that FGF21 acts via the brain's reward pathway in mice to suppress the desire for sugar and alcohol in favor of drinking water.

Mice in booze camp In the new study, performed on adolescent male mice, ethanol alcohol exposure seemed to enhance synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathMice in booze camp In the new study, performed on adolescent male mice, ethanol alcohol exposure seemed to enhance synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathmice, ethanol alcohol exposure seemed to enhance synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathway.

They got similar results when they engineered mice to lack another immune molecule, suggesting that B2M is part of a pathway that affects the brain.

In contrast to past patchwork attempts, Dong and his team undertook an effort to directly develop a whole - brain mouse atlas of brain pathways.

The genes went to work in the auditory pathways of the mouse brains, creating light - sensitive patches on the membranes of their spiral ganglion neurons and other neurons.

«If you're looking for very specific molecular targets or pathways in the brain, and how drugs might act on them, the difference between human cells and mouse cells is significant.»

The CUMC team is currently using the new mouse model to study signaling pathways in the brain that drive anorexic behavior, with the ultimate goal of identifying therapeutic targets.

The research team carried out behavioural studies in mice and investigated how pathways in their brains operate under THC.

In their research the team blocked a particular inflammatory signalling pathway (IKKβ / NF - κB) in the brains of obese mice.

When the researchers used optogenetics, a biological technique which involves the use of light to control neurons, to inhibit the key social - spatial pathway they had identified in the brain, the test mouse wandered freely through the space.

Researchers aiming to understand why autism spectrum disorders (ASD) are more common in boys have discovered differences in a brain signaling pathway involved in reward learning and motivation that make male mice more vulnerable to an autism - causing genetic glitch.

«Signaling pathway may be key to why autism is more common in boys: In mice, the male brain is vulnerable and the female brain resilient to a genetic cause of autism.»

«Inhibition of the EZH2 pathway slows growth of tumors in mouse brain derived from glioma stem cells from the enhancing margin of human tumors.

The researchers showed that the mTOR pathway correlates with brain improvements observed in their mice and suggest that future studies might test whether the pathway is necessary to mediate such improvements.

Brainbow, by Jean Livet / Harvard Center for Brain Science (2007) This image marked the first time that it was easy for researchers to see the pathways taken by many neurons in a brain (in this case, a mouse brBrain Science (2007) This image marked the first time that it was easy for researchers to see the pathways taken by many neurons in a brain (in this case, a mouse brbrain (in this case, a mouse brainbrain).

They also found that drugs that target this newly identified cancer pathway can prevent tumor growth, both in human cancer cells and mice with a form of brain cancer.

Protein profiles in the Dp (10) 1Yey and Dp (17) 1Yey mice predict novel pathway perturbations in the Down syndrome brain and sex - specific abnormalities in protein levels

Researchers have identified a brain pathway that plays an important role in making survival decisions — such as a mouse's decision to flee rather than try to mate when confronted by a cat.

Working in zebra fish and mouse brain cells, researchers found evidence that ACVR1 mutations from DIPG resulted in the BMP pathway being inappropriately and permanently switched on.

The scientists used optogenetics — an innovative research tool that uses light to activate or inhibit select cells in the brain — to stimulate either the go or the stop pathway in mice that were running on a tiny treadmill, while recording neural activity in the brainstem.

They relate these results to those in laboratory animals, such as mice and rats, which offer a window on the pathways by which exercise can enhance brain health.

The reason mice are so helpful in studying addiction is because the reward pathway in our brains functions in much the same way in mice as it does in people.