Sentences with phrase «mouse cardiac tissue»
Because they are interested in human heart failure, Lavine and his colleagues developed a method to progressively damage mouse cardiac tissue in a way that mimicked heart failure.
https://www.sciencedaily.com/ Not exact matches
The researchers transplanted the cardiac fibroblasts isolated from the region of calcification under the skin of healthy mice and observed soft - tissue calcification similar to that seen in the donor mice.
In a study published online in Circulation Research late last year, Chaudhry and colleagues found that fetal cells in mice migrated to the mother's heart, differentiated into functioning cardiac cells, and accelerated repair to damaged heart tissue.
«And when we examined the heart tissue of the mice that survived, we found that they had developed major regions of cardiac muscle tissue death.»
As the investigators note, the rapid age - related arterial stiffening and cardiac arrhythmias that appear to be at cause for the majority of deaths in BubR1H / H mice were not attenuated by ablating p16Ink4a - expressing senescent cells — but these tissues had little burden of such cells, so this finding reinforces the conclusion that the multiple aging phenotypes arrested in these mice when senescent cells were ablated is attributable specifically to the removal of their baleful influence on local tissues.