So she did, and there an expert told her: «Oh no,
mouse ear holes absolutely do not close.»
Not exact matches
Ellen Heber - Katz, a scientist at The Wistar Institute in Philadelphia, used to study autoimmunity — that was until she noticed something strange in the
mice she was using to model lupus: The small
holes that she had poked in their
ears to distinguish the animals from one another kept closing.
Heber - Katz says another scientist working with the
mouse model of lupus also noticed the closing
ear holes, but thought of it as an inconvenience rather than a eureka moment, saying, «These darn
mice, you have to keep going upstairs to punch
holes in their
ears!»
The difference might be subtle: Researchers have identified one strain of
mice that seals up
ear holes in weeks, whereas typical strains never do.
As with the
mice, the team will inject the viral gene package directly into the volunteers» cochlea by peeling back their
ear drum and passing a needle through a tiny
hole made by a laser (see diagram).
Holes punched into the
ears to tag the
mice, she says, healed without any signs of scar tissue.
In the course of his cancer research George Daley of Children's Hospital Boston and Harvard Medical School was trying to clip
holes in the
ears of genetically engineered
mice so he could tell them apart when, surprisingly, the wounds kept healing.
Heber - Katz made her discovery after noticing that identification
holes punched into the
ears of experimental
mice healed without any apparent scarring, according to Boston University.