Not exact matches
Bones make hormones that chat with other organs and
tissues, including the brain,
kidneys and pancreas, experiments in
mice have shown.
After giving the cells a week to get used to each other, the scientists implanted the chimeric concoction into the protective
tissue surrounding the
kidneys of living
mice.
Gorelick would also like to make sure that no dangerous levels of radiation are released as the bacteria die, noting that some buildup was seen in the
kidney tissue of the
mice treated in the new study.
So we tested this in
mouse models and in human polycystic
kidney tissues, and, in both cases, high levels of pIgR were expressed in
kidney cysts.»
Through studies conducted in
mice, Oliver M. Steinmetz, MD (University Hospital Hamburg Eppendorf, in Germany) and his colleagues have shown that the messenger protein IL - 6, which is rapidly produced at high levels during an acute inflammatory form of
kidney disease, potently dampens activation of
tissue - destructive immune cells called macrophages.
After transplanting the human iPS cell - based
kidney tissue into a
mouse body, glomeruli connecting to
mouse kidney capillaries formed.
«Our stem cells also survive outside of
mice, in a culture, so we can also manipulate them in a laboratory,» said Abad, adding that: «The next step is studying if these new stem cells are capable of efficiently generating different
tissues such as that of the pancreas, liver or
kidney.»
Rare stem cells (in red) that give rise to scar -
tissue secreting myofibroblast cells, here found near the blood vessels of a
mouse kidney (in green).
The absolute wet weight of heart, spleen, and
kidney tissues was significantly lower in IL - 15Rα — KO
mice compared with B6129
mice.
The researchers analyzed the concentrations of 5,713 different lipids, or fat molecules and their derivatives, present in samples of brain,
kidney and muscle
tissues taken from humans, chimpanzees, macaques and
mice.
On the other hand, there are many other
tissues — notably, the
kidney and articular cartilage — where p16Ink4a - expressing senescent cells appear to be a contributing factor to human and murine degenerative aging, but which were not evaluated in treated or control
mice in this study, and it would be of interest to see the effects of ablation of p16Ink4a - positive senescent cells.
Studying cells from the stomach and pancreas in humans and
mice, as well as
mouse kidney and liver cells, and cells from more than 800 tumor and precancerous lesions in people, the researchers found when
tissue is injured by infections or trauma, mature cells can revert back to a stem - cell state in which they divide repeatedly.
He later combined it with studies on chromatin,
tissue specific gene expression and
mouse models for human diseases including Type II diabetes, polycystic
kidney disease as well as cancer.
When normal
mice were exposed to TNF, all
tissues studied (liver,
kidney, spleen, thymus, colon, and lymph nodes) produced large amounts of A20 and the
mice survived unharmed.